Neuroinflammation: Advancements in Pathophysiology and Therapies (2nd Edition)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 2221
Special Issue Editor
2. Departamento de Farmacología y Toxicología, Facultad de Medicina, Instituto de Investigación Hospital 12 de Octubre (i+12), Instituto Universitario de Investigación en Neuroquímica (IUIN), Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain
Interests: neuropsychopharmacology; inflammation; microbiome; glía; barrier function; psychiatric diseases; schizophrenia; depression
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuroinflammation stands as a pervasive phenomenon that cuts across various conditions that affect the central nervous system (CNS), encompassing neurological, neurodegenerative, cardiovascular, and psychiatric disorders. Furthermore, neuroinflammation might also have a role in physiological processes such as aging. In essence, inflammation is a homeostatic mechanism triggered by stimuli of diverse nature to protect the organism. However, if the inflammatory process falters in eliminating potential menaces and persists over time, it can hamper normal CNS function and contribute to disease development. Despite the etiological responsibilities of neuroinflammation sparking an intense debate, its concurrence and consequences represent a harmful threat and may exacerbate the progression and severity of CNS diseases. In this context, a wealth of meta-analyses and an expanding body of clinical and preclinical data underscore the efficacy of anti-inflammatory treatments in some facets of these pathologies, supporting the fact that uncontrolled and chronic neuroinflammation endangers the CNS. Nevertheless, the precise molecular mechanisms underpinning neuroinflammation, its significance for the pathophysiology of certain diseases, and the search for novel therapies aimed at modulating neuroinflammation for clinical improvement remain limited, thereby necessitating further research.
This Special Issue aims to provide a broad overview of the latest cutting-edge advancements in neuroinflammation research, emphasizing its role in the pathophysiology of diseases and innovative treatment strategies. We welcome original research articles, reviews, brief reports, or any other contributions dealing with the following:
- Molecular, cellular, and tissue-level mechanisms governing neuroinflammation and their regulatory pathways;
- Neuroinflammation in the pathophysiology of CNS or systemic diseases;
- Emerging pharmacological approaches for managing or modulating neuroinflammation.
We hope that Special Issue will serve as a trove of recent and current knowledge for newcomers and experienced scientists in this dynamic field.
Dr. David Martín-Hernández
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroinflammation
- CNS diseases
- pathophysiology
- therapeutic strategies
- pharmacological treatments
- neurological disorders
- neurodegenerative diseases
- cardiovascular diseases
- psychiatric disorders
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
