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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Immune Regulation of Osteoclasts
edited by
submission deadline 23 Oct 2026 | Viewed by 431 | Submission Open
Keywords: hematopoietic stem cells; osteoclasts; osteoblasts; osteocytes; stromal cells; T cells; B cells; macrophages; dendritic cells; interleukins; cytokines
(This special issue belongs to the Section Molecular Immunology)
Nanotechnology for Food Science—Innovations and Sustainable Solutions
edited by
submission deadline 23 Oct 2026 | Viewed by 387 | Submission Open
Keywords: nanotechnology; nanomaterial synthesis; food safety; food science; nano-engineered food additives; nano-sensors
(This special issue belongs to the Section Molecular Nanoscience)
Advances in the Role of Retinoic Acid-Regulated Genes in Cancer Biology
edited by Fuming Tsai
submission deadline 23 Oct 2026 | Viewed by 349 | Submission Open
Keywords: retinoic acid; retinoic acid receptors; retinoic x receptors; tumorigenesis; metastasis; tumor microenvironment; molecular pathways
(This special issue belongs to the Section Molecular Genetics and Genomics)
Targeted Therapy for Breast and Gynecological Cancer
edited by Moira Ragazzi and Elisa Gasparini
submission deadline 23 Oct 2026 | Viewed by 340 | Submission Open
Keywords: breast cancer; gynecological cancer; target therapy; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Aging and Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics—2nd Edition
edited by Lilach Soreq
submission deadline 23 Oct 2026 | Viewed by 334 | Submission Open
Keywords: aging; Alzheimer’ s disease; bioinformatics; RNA-seq; Parkinson’ s disease
(This special issue belongs to the Section Molecular Neurobiology)
Prostate Cancer: Molecular Mechanisms and Targeting
edited by
submission deadline 23 Oct 2026 | Viewed by 325 | Submission Open
Keywords: prostate cancer; androgen receptor; therapy resistance; epigenetics; tumor microenvironment; molecular signaling; precision oncology
(This special issue belongs to the Section Molecular Oncology)
The Structure, Function, and Application of Zinc Finger Proteins
edited by
submission deadline 23 Oct 2026 | Viewed by 286 | Submission Open
Keywords: zinc finger proteins: structure; function and properties; applications; protein folding and dynamics; environmental contaminants and metal ions exposure; uptake; toxicity; molecular recognition and signal transduction; mechanisms of action and effects of abnormal zinc finger proteins on human health; zinc finger proteins as drug targets
(This special issue belongs to the Section Molecular Biology)
Nanomaterials in Biomedicine, Microbiology and Tissue Engineering submission deadline 23 Oct 2026 | Viewed by 206 | Submission Open
Keywords: nanomaterials; nanotechnology; biomedicine; microbiology; tissue regeneration
(This special issue belongs to the Section Materials Science)
Microbial Enzymes for Biotechnological Applications: 2nd Edition
edited by
submission deadline 25 Oct 2026 | 5 articles | Viewed by 20110 | Submission Open
Keywords: microbial enzymes; whole-cell biocatalysts; extremozyme; enzyme assays; protein engineering
(This special issue belongs to the Section Biochemistry)
Biochemical Perspectives on Diabetes
edited by Antonio Maria Labate
submission deadline 25 Oct 2026 | Viewed by 325 | Submission Open
Keywords: diabetes; biochemistry; biomarkers; insulin resistance; cardiometabolic risk; inflammation; oxidative stress; diabetic complications
(This special issue belongs to the Section Biochemistry)
Research Progress on Neuroinflammation
edited by Abhishek Jauhari
submission deadline 25 Oct 2026 | Viewed by 271 | Submission Open
Keywords: neuroinflammation; mitochondria; microglia; inflammasome; cGAS; STING
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Macromolecular Drug Design and Research submission deadline 25 Oct 2026 | Viewed by 170 | Submission Open
Keywords: macromolecular drug design; polymer therapeutics; nanomedicine; bioconjugation; antibody– drug conjugates; peptide therapeutics; nucleic acid delivery; targeted drug delivery; controlled release; translational therapeutics
(This special issue belongs to the Section Molecular Pharmacology)
Advances in Molecular Mechanisms of Inflammatory Skin Diseases
edited by Xuming Mao
submission deadline 25 Oct 2026 | Viewed by 107 | Submission Open
Keywords: inflammatory skin diseases; dermatitis; psoriasis; inflammation
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanism in Corrosion
edited by
submission deadline 28 Oct 2026 | Viewed by 374 | Submission Open
Keywords: molecular corrosion mechanisms; microbiologically influenced corrosion (MIC); biofilm formation on metal surfaces; electrochemical– biological coupling; biocorrosion pathways; molecular adsorption of corrosion inhibitors; enzymatic corrosion processes; surface passivation and biofilm dynamics; molecular modeling of corrosion; microbial community analysis; corrosion protection; high temperature corrosion; corrosion in oil and gas industries; reinforced steel bar corrosion
(This special issue belongs to the Section Materials Science)
Circulating Molecular Markers and Redox Signaling in Endocrine Disorders
edited by Antonio Mancini and
submission deadline 28 Oct 2026 | Viewed by 113 | Submission Open
Keywords: antioxidant defense; metabolic syndrome; endocrine disorders; redox signaling; circulating biomarkers
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Mechanisms and Intervention Strategies in Cardiovascular and Cerebrovascular Diseases
edited by Rossana Scuri
submission deadline 28 Oct 2026 | Viewed by 60 | Submission Open
Keywords: cardiovascular diseases; cerebrovascular diseases; therapeutic interventions; regenerative medicine; endothelial dysfunction; cardiac remodeling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Melanin Pigmentation: Physiology and Pathology submission deadline 30 Oct 2026 | 9 articles | Viewed by 14652 | Submission Open
Keywords: eumelanin; pheomelanin; melanogenesis; photoprotection; pigmentary disorders; depigmenting agents; extracutaneous melanins
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Updates and Advances in the Field of Glioblastomas: Mechanisms, Microenvironment and Treatments
edited by
submission deadline 30 Oct 2026 | 6 articles | Viewed by 8585 | Submission Open
Keywords: GBM; molecular classification; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; immunotherapy; targeted therapies for GBMs
(This special issue belongs to the Section Molecular Oncology)
Molecular Research in Skin Health and Disease
edited by
submission deadline 30 Oct 2026 | 3 articles | Viewed by 6638 | Submission Open
Keywords: wound healing; molecular research in skin lesions; dermatologic surgery; cosmetic surgery; exosomes: new molecular targets of diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Therapeutics for Respiratory Diseases
edited by
submission deadline 30 Oct 2026 | 2 articles | Viewed by 6539 | Submission Open
Keywords: lung diseases; cystic fibrosis; chronic obstructive pulmonary disease; asthma; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Role of Anthranilic Acid in Neuropsychiatric Diseases submission deadline 30 Oct 2026 | 2 articles | Viewed by 5121 | Submission Open
Keywords: anthranilic acid; Alzheimer’ s disease; autism; schizophrenia; bipolar disorder; major depressive disorder; post-partum depression; COVID-19; interferons; attention deficit disorder; cognitive impairment; G-protein-coupled receptor 109A; microbiome; gut– brain axis
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Genetics and Breeding Research in Horticultural Crops
edited by
submission deadline 30 Oct 2026 | 3 articles | Viewed by 4507 | Submission Open
Keywords: horticultural crops; genomic sequencing; multi-omics technologies; molecular biology; gene editing; plant breeding; function of genes; molecular marker
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Microbial Genomics: Insights from Whole Genomes and Metagenomes submission deadline 30 Oct 2026 | 4 articles | Viewed by 4315 | Submission Open
Keywords: microbial evolution; whole-genome sequencing; metagenomics; horizontal gene transfer; antimicrobial resistance; computational genomics
(This special issue belongs to the Section Molecular Genetics and Genomics)
Biomechanics of Cardiovascular Remodeling
edited by and Maximilian Doldi Philipp
submission deadline 30 Oct 2026 | 2 articles | Viewed by 4206 | Submission Open
Keywords: cardiovascular remodeling; cardiac imaging; cardiovascular intervention; cardiovascular pathways; cardiovascular research; structural heart disease; cellular signaling
(This special issue belongs to the Section Molecular Biophysics)
The Impact of Oxidative Stress on Male and Female Germ Cells: From Redox Biology to Photon Emission
edited by and Kálmán András Kovács
submission deadline 30 Oct 2026 | 1 articles | Viewed by 4143 | Submission Open
Keywords: oxidative stress; germ cells; fertility; redox signaling; mitochondrial dynamics; DNA damage; photonic communication; ultra-weak photon emission; quantum biology; reproductive health
(This special issue belongs to the Section Biochemistry)
Collagen and Its Derivatives in Tissue Engineering
edited by
submission deadline 30 Oct 2026 | 2 articles | Viewed by 2864 | Submission Open
Keywords: collagen derivatives; tissue engineering; in vitro experiments; in vivo investigations; material degradation
(This special issue belongs to the Section Biochemistry)
Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy: 2nd Edition
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 2691 | Submission Open
Keywords: immune checkpoints; targeted therapies; tumor microenvironment; cancer immunology; precision medicine; cell-based cancer therapy
(This special issue belongs to the Section Molecular Immunology)
Latest Molecular Research in Plant Secondary Metabolism
edited by
submission deadline 30 Oct 2026 | 2 articles | Viewed by 2470 | Submission Open
Keywords: plants; plant in vitro systems; secondary metabolism; metabolite profiling and fingerprinting; sustainable production; elicitation; metabolic engineering; CRISPR/Cas; molecular targets
(This special issue belongs to the Section Molecular Plant Sciences)
Focus on the Tryptophan Pathway
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 2452 | Submission Open
Keywords: aging; indole-3-propionic acid; kynurenic acid; melatonin; serotonin; tryptophan
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Microbial Natural Products
edited by Wenli Li
submission deadline 30 Oct 2026 | 2 articles | Viewed by 2446 | Submission Open
Keywords: microbial natural products; biosynthetic gene clusters; structural elucidation; metabolic engineering; synthetic biology; bioactivity profiling; sustainable biomanufacturing
(This special issue belongs to the Section Molecular Microbiology)
Advanced Plant Molecular Responses to Abiotic Stresses: 2nd Edition
edited by
submission deadline 30 Oct 2026 | 3 articles | Viewed by 2384 | Submission Open
Keywords: abiotic stress responses (heat; drought; salinity; nutrient deficiency; oxygen quality; flooding; light; etc.); genetically modified plants; CRISPR/Cas-mediated stress overcome; microplastic/nanoparticle stresses; bioinformatic studies; miRNAs and other noncoding RNAs involved in abiotic stresses in plants; secondary metabolite synthesis
(This special issue belongs to the Section Molecular Plant Sciences)
Intermittent Hypoxia: Physiological and Biomedical Perspectives
edited by , and Norma Alva
submission deadline 30 Oct 2026 | 2 articles | Viewed by 2147 | Submission Open
Keywords: altitude training; cardiovascular adaptation; endothelial dysfunction; EPO; intermittent hypoxia conditioning programs; HIF-1; neuroplasticity; obstructive sleep apnea; oxidative stress; pulmonary hypertension
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases, 3rd Edition
edited by
submission deadline 30 Oct 2026 | 2 articles | Viewed by 1773 | Submission Open
Keywords: cardiovascular diseases; metabolic diseases; cellular and molecular mechanisms
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advance in Plant Abiotic Stress: 4th Edition
edited by and
submission deadline 30 Oct 2026 | 2 articles | Viewed by 1669 | Submission Open
Keywords: abiotic stress; cold; drought; salt; heat; nutrient deficiency; secondary metabolism; stress resistance; plant
(This special issue belongs to the Section Molecular Plant Sciences)
The Roles of Oxidative Stress in Metabolic Syndrome submission deadline 30 Oct 2026 | 1 articles | Viewed by 1263 | Submission Open
Keywords: oxidative stress; metabolic syndrome; inflammation; antioxidants; human chronic diseases; cardiometabolic diseases; nutrition; lifestyle
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Lipid Membranes as Multifunctional Platforms for Bioactive Delivery
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 1180 | Submission Open
Keywords: lipid-based carriers; drug delivery; bioactive compounds; in silico; in vitro and in vivo models
(This special issue belongs to the Section Macromolecules)
The Zebrafish Model in Animal and Human Health Research, 3rd Edition
edited by and Federica Scalia
submission deadline 30 Oct 2026 | 2 articles | Viewed by 1138 | Submission Open
Keywords: zebrafish; environmental toxicology; predictive toxicology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Bowel Disease: From Genetics to Therapy
edited by Paweł Petryszyn
submission deadline 30 Oct 2026 | 1 articles | Viewed by 948 | Submission Open
Keywords: inflammatory bowel disease; IBD genetics; genomics and multi-omics; polygenic risk; precision medicine; therapeutic targets; disease prediction
(This special issue belongs to the Section Molecular Genetics and Genomics)
Arthritis: From Molecular Basis to Therapy
edited by Cinzia Rotondo
submission deadline 30 Oct 2026 | 2 articles | Viewed by 936 | Submission Open
Keywords: comorbidities; biomarkers; inflammation; autoimmune disease; systemic disease; arthritis; autoimmune disease; psoriasis; axial involvement; biological drugs; target synthetic DMARDs; pathogenesis; rheumatoid arthritis; spondyloarthritis; psoriatic arthritis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments, 2nd Edition
edited by
submission deadline 30 Oct 2026 | 2 articles | Viewed by 927 | Submission Open
Keywords: lupus erythematosus; lupus nephritis; SLE; LN; organ damage; pathogenesis; biomarkers; genomic; transcriptomic; metabolomic; treatments; therapeutic
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism in Pulmonary Embolism
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 891 | Submission Open
Keywords: pulmonary embolism; thrombosis; molecular mechanisms; coagulation; endothelial dysfunction; biomarkers; inflammation; fibrinolysis; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Lipedema: Pathophysiology, Prevention and Treatments
edited by Angelika Chachaj
submission deadline 30 Oct 2026 | Viewed by 872 | Submission Open
Keywords: lipedema; microvascular dysfunction; inflammation; lipedema diagnosis; biomarkers; diet in lipedema; quality of life; compression therapy; liposuction
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Antimicrobial Nanoparticles
edited by and
submission deadline 30 Oct 2026 | 1 articles | Viewed by 791 | Submission Open
Keywords: antimicrobial nanoparticles; resistant pathogens; antimicrobial resistance; lipid nanoparticles; biomimetic nanostructures; combined therapy; antimicrobial strategies
(This special issue belongs to the Section Molecular Nanoscience)
Alcohol Use Disorder: From Molecular Mechanisms to Therapeutics submission deadline 30 Oct 2026 | 2 articles | Viewed by 791 | Submission Open
Keywords: alcohol; addiction; FASD; alcohol-related damage
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cell Biology of Viruses
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 687 | Submission Open
Keywords: molecular virology; cellular virology; virus– host interface; intracellular trafficking; cellular pathogenesis
(This special issue belongs to the Section Molecular Microbiology)
Precision Photosynthesis: Mechanisms and Applications in Controlled Environments
edited by
submission deadline 30 Oct 2026 | 1 articles | Viewed by 676 | Submission Open
Keywords: controlled environment agriculture (CEA); photobioreactor; plant growth chamber; light-emitting diode (LED) spectrum; photosynthetic efficiency; acclimation; synthetic biology; metabolic engineering; high-throughput phenotyping; predictive modeling; vertical farming
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Techniques to Study Food Safety Challenges submission deadline 30 Oct 2026 | Viewed by 543 | Submission Open
Keywords: food safety; hazards; foodborne pathogens; advanced microbial detection technologies; omics techniques; preventive measures
(This special issue belongs to the Section Molecular Microbiology)
Neuro-Immune-Endocrine Systems: Mechanisms, Biomarkers, and Disease Implications
edited by Grażyna Gromadzka
submission deadline 30 Oct 2026 | Viewed by 541 | Submission Open
Keywords: neuro-immune-endocrine interactions; aging; autoimmune diseases; metabolic disorders; cancer; neuropsychiatric disorders; neuroinflammation; molecular signaling; biomarkers; translational research
(This special issue belongs to the Section Molecular Neurobiology)
Artificial Intelligence in Nano- and Bio-Technology Systems: Focus on Molecular Research
edited by
submission deadline 30 Oct 2026 | Viewed by 492 | Submission Open
Keywords: artificial intelligence; nanotechnology; biotechnology; medicine; energy systems; blockchain
(This special issue belongs to the Section Molecular Nanoscience)
Research Advances in Photodynamic Therapy submission deadline 30 Oct 2026 | Viewed by 430 | Submission Open
Keywords: photodynamic therapy (PDT); photosensitizers and nanocarriers; targeting and molecular selectivity; photophysics and dosimetry; anticancer and antimicrobial applications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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