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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Syndrome: New Insights in Pathogenesis, Diagnosis, Prevention, and Management

edited by

Lucia Maria Procopciuc

and

Roxana Liana Lucaciu

submission deadline 20 Sep 2025 | 7 articles | Viewed by 9854 | Submission Open

Keywords: insulin resistance; hypertension; diabetes mellitus; obesity; inflammation; stress; metabolic disorders; reproductive endocrine disorders; polycystic ovarian syndrome; waist circumference; estrogen deficiency; disturbances in adipose tissue; physical inactivity; overnutrition; cardiovascular diseases; abdominal obesity; genetics and epigenetics of metabolic syndrome; computational analysis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular and Translational Research on Bone Tumors, 2nd Edition

edited by

Michela Rossi

and

Andrea Del Fattore

submission deadline 20 Sep 2025 | 2 articles | Viewed by 9717 | Submission Open

Keywords: primary bone tumours; metastatic bone tumour; therapy; biomarkers; epigenetic factors; immune-oncology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology and Hormonal Regulation in Reproductive Processes

edited by

Martin Stimpfel

and Helena Ban Frangež

submission deadline 20 Sep 2025 | 4 articles | Viewed by 9412 | Submission Open

Keywords: infertility; reproduction; embryos; genetics; epigenetics; signaling pathway; sperm; oocyte

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Tau Pathobiology in Neurodegenerative Diseases: From Molecular Mechanisms to Therapeutic Advances

edited by

Valentina Latina

and

Giuseppina Amadoro

submission deadline 20 Sep 2025 | 3 articles | Viewed by 9152 | Submission Open

Keywords: Alzheimer’ s disease; tauopathies; tau neurotoxicity; cellular and animal models; signaling pathways; tau-targeting therapies

(This special issue belongs to the Section Molecular Neurobiology)

102nd Anniversary of Neurotransmitter Discovery: Cholinergic Pathways in Physiology and Pathophysiology

edited by

Sumonto Mitra

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8665 | Submission Open

Keywords: acetylcholine; physiological functions; pathological alterations; cholinergic pathways

(This special issue belongs to the Section Biochemistry)

The Zebrafish Model in Animal and Human Health Research, 2nd Edition

edited by

Antonella Marino Gammazza

and

Marta Anna Szychlinska

submission deadline 20 Sep 2025 | 6 articles | Viewed by 8146 | Submission Open

Keywords: zebrafish; environmental toxicology; predictive toxicology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Dysfunction: A Metabolic, Cardiovascular, Neurodegenerative and Neuromuscular Issue: 2nd Edition

edited by

Stefano Doccini

Federica Morani

and Claudia Nesti

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7985 | Submission Open

Keywords: bioenergetics; mitochondrial disorders; biomarkers; OxPhos complexes; mitochondrial DNA; aging; neurodegenerative diseases; cardiovascular diseases; metabolic diseases; therapies to counteract mitochondrial dysfunction TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Bacteria

edited by

Giovanni Stelitano

submission deadline 20 Sep 2025 | 10 articles | Viewed by 7740 | Submission Open

Keywords: infections; bacteria; molecular biology; antimicrobials; bacterial enzymes; bioremediation

(This special issue belongs to the Section Molecular Microbiology)

State-of-the-Art Molecular Oncology in Brazil, 3rd Edition

edited by

Tiago Rodrigues

and

Roger Chammas

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7410 | Submission Open

Keywords: apoptosis; autophagy; calcium; cancer; cell death; chemotherapy; metabolism; mitochondria; drug resistance; oxidative stress

(This special issue belongs to the Section Molecular Oncology)

Molecular Insight into the Processing and Characterization of Animal Fats and Vegetable Oils

edited by

Pavel Mokrejš

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7394 | Submission Open

Keywords: lipid molecules; oils; fats; lipase; interesterification; hydrolysis; phospholipids; fatty acids; molecular research; nutrition; cosmetics matrices; medical applications; food; pharmacy; bioengineering; novel applications; biofuels

(This special issue belongs to the Section Molecular Biology)

Advances in Genetics of Human Reproduction

edited by

Jasenka Wagner

and

Borut Peterlin

submission deadline 20 Sep 2025 | 6 articles | Viewed by 7297 | Submission Open

Keywords: genetic; human reproduction; infertility; medically assisted reproduction; pregnancy complications; recurrent miscarriage

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Plant Abiotic Stress Tolerance: 2nd Edition

edited by

Michael Moustakas

submission deadline 20 Sep 2025 | 6 articles | Viewed by 7228 | Submission Open

Keywords: acclimation; drought; salinity; pesticides; high– low temperature; high– low light intensity; nutrient deficiencies; heavy metals; UV radiation; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Zebrafish as a Model in Human Disease: 3rd Edition

edited by

Andrea Vettori

Nicola Facchinello

and

Marco G. Schiavone

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7111 | Submission Open

Keywords: zebrafish; CRISPR/Cas9; transgenic lines; biosensors; endothelial cells; extracellular matrix; genetic mutant for human disease modeling; xenografts

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: Pain

edited by

Sebastiano Mercadante

and

István Nagy

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6911 | Submission Open

Keywords: cancer; inflammation; neuropathy; primary sensory neurons; spinal cord; brain

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research in Spinal Cord Injury

edited by

Inbo Han

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6859 | Submission Open

Keywords: spinal cord injury; molecular mechanisms; stem cell therapy; tissue engineering; neuroinflammation; neuroprotection; genetic regulation; epigenetics; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research of Epithelial Function and Barrier Dysfunction

edited by Fariba Rezaee

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6796 | Submission Open

Keywords: epithelial cells; actin cytoskeleton; viral infection; apical junctional complex; tight junction; adherens junction; barrier dysfunction; trans-epithelial electrical resistance; permeability; epithelial barrier

(This special issue belongs to the Section Molecular Immunology)

Mycotoxins, Immunity, and Inflammation

edited by

Yuseok Moon

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6783 | Submission Open

Keywords: mycotoxin; immunity; inflammation; immunotoxicity; immunology

(This special issue belongs to the Section Molecular Toxicology)

Current Advances and Perspectives in Microbial Genetics and Genomics

edited by

Marcello Tagliavia

and Lucila Saavedra

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6722 | Submission Open

Keywords: microbial genetics; genomics and metagenomics; gene regulation; microbe– host interactions; adaption and resistance mechanisms; microbial metabolism

(This special issue belongs to the Section Molecular Microbiology)

Molecular Biology of Protein Kinases: Regulatory Mechanisms, Therapeutic Targets and Cancer Treatments

edited by Jaw Ji Yang

submission deadline 20 Sep 2025 | 2 articles | Viewed by 6695 | Submission Open

Keywords: protein kinases; signal transduction; cancer therapy; regulatory mechanisms; kinase inhibitors; therapeutic targets; molecular biology; structural biology; translational research; clinical applications

(This special issue belongs to the Section Molecular Biology)

The Role and Mechanism of P2X7 Receptor in Cancer and Inflammatory Diseases

edited by

Anna Lisa Giuliani

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6551 | Submission Open

Keywords: P2X7 receptor; inflammation; cancer; purinergic signalling

(This special issue belongs to the Section Molecular Immunology)

Advanced Research of Metallic Nanoparticles

edited by

Edyta Proniewicz

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6547 | Submission Open

Keywords: metallic nanoparticles (MNPs); biosensors; synthesis methods; molecular spectroscopy characteristic; molecular medicine; molecular biology

(This special issue belongs to the Section Molecular Nanoscience)

Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants

edited by

Katarzyna Hnatuszko-Konka

and

Izabela Grzegorczyk-Karolak

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6342 | Submission Open

Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Pathophysiology of Sepsis

edited by

Vlad Pădureanu

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6295 | Submission Open

Keywords: animal models; therapeutic concepts; biomarkers; sepsis; immune suppression; epigenetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of Natural Compounds in Human Health and Disease

edited by Jaewon Shim and

Wook-bin Lee

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6272 | Submission Open

Keywords: natural compound; therapeutic applications; action mechanisms of natural compounds; traditional medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances and Insights into Liver Diseases

edited by

Jacek Baj

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6242 | Submission Open

Keywords: liver; hepatocellular carcinoma; cancer; hepatitis; cirrhosis; encephalopathy; non-alcoholic fatty liver disease; autoimmune diseases; Wilson’ s disease; fatty liver disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Anti-cancer Drug Discovery and Development

edited by

Ki-cheong Park

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6210 | Submission Open

Keywords: anti-cancer drug resistant; cancer recurrence; cancer metastasis; cancer stem cells; target validation; target identification; metabolic reprogramming of cancer stem cells; unmet medical needs

(This special issue belongs to the Section Molecular Pharmacology)

Viral Infections and Immune Responses

edited by

Alessandra Ruggiero

and

Marco Iannetta

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6083 | Submission Open

Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralizing activity

(This special issue belongs to the Section Molecular Immunology)

The Biochemistry, Molecular and Cell Biology Beyond Flowers

edited by

Isabel Marques

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5953 | Submission Open

Keywords: flowers; homeotic genes; MADSBox; molecular expression; pollination; stress; transcription factors

(This special issue belongs to the Section Molecular Plant Sciences)

State-of-the-Art Molecular Immunology in Chile, 2nd Edition

edited by

Marcela Hernandez Ríos

Juan C. Aguillon

, María Rosa Bono,

Nicolas Dutzan

Rolando Vernal

and

Leandro J. Carreño

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5952 | Submission Open

Keywords: innate immunity; adaptive immunity; host– pathogen interactions; immunopathology; osteoimmunology; immunosenescence; immunotherapy; antibody; vaccines; Chile

(This special issue belongs to the Section Molecular Immunology)

Drug Discovery: Design, Synthesis and Activity Evaluation

edited by

Joana L. C. Sousa

and

Artur M. S. Silva

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5831 | Submission Open

Keywords: drug design; organic synthesis; biological activity evaluation; biologically active compounds; diagnostic/therapeutic agents; labeled ligands; structure– activity relationships (SARs); structural biological studies; computational studies; pharmacokinetics/pharmacodynamics; drug delivery

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Physiological Mechanisms of Exercise

edited by Zoran Nikolovski

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5796 | Submission Open

Keywords: molecular biology; biochemistry and exercise; athletic performance; multi-omic

(This special issue belongs to the Section Molecular Biology)

Arrhythmias: Molecular Mechanisms and Therapeutic Strategies

edited by

Yung-Lung Chen

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5791 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; ventricular arrhythmia; electrophysiologic alternation; ion channel; connexin; autonomic nerve system dysfunction; sleep-disordered breathing; obstructive sleep apnea

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Apoptosis and Autophagy as Strategies in Cancer Treatment

edited by Dorota Ciołczyk-Wierzbicka

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5582 | Submission Open

Keywords: apoptosis; autophagy; cancer therapy/treatment; drug resistance; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Research for Legume Genomics, Genetics, and Breeding, 2nd Edition

edited by

Naoufal Lakhssassi

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5580 | Submission Open

Keywords: legumes; genomics; plant breeding; seed composition; gene function; biotic and abiotic stress; legume pathogen resistance/mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Exploring the Pathogenetic Mechanisms in Respiratory Virus Infections: Recent Advances and Future Directions

edited by

Marta De Angelis

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5269 | Submission Open

Keywords: respiratory viruses; virus-host interactions; inflammation; metabolic pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Microbe–Skin Interactions

edited by

Friedrich Götz

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5063 | Submission Open

Keywords: colonization; cosmetics; diseases (e.g.; acne; diabetic foot syndrome (DFS); psoriasis; etc.); health; immunity; lipidomics; metabolomics; metagenomics; neurotransmitter; physiology; skin habitat; skin microbiota; prebiotics; probiotics; wound healing

(This special issue belongs to the Section Molecular Microbiology)

New Insights in Prion Diseases

edited by

Eva Bagyinszky

submission deadline 20 Sep 2025 | 1 articles | Viewed by 5058 | Submission Open

Keywords: prion diseases; prion mutation; genetic modifier; neurodegenerative diseases; therapy; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Noncovalent Interactions and Applications in Materials and Catalysis

edited by Snežana D. Zarić

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4935 | Submission Open

Keywords: noncovalent interactions; materials; catalysis; crystal structures; quantum chemistry calculations; hydrogen bonds; stacking interactions; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Basis of Pancreatic Secretion and Metabolism

edited by

Dongki Yang

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4920 | Submission Open

Keywords: exocrine of the pancreas; endocrine of the pancreas; acute pancreatitis; chronic pancreatitis; cystic fibrosis; pancreatic metabolic hormones; pancreatic metabolic disease; mechanism of pancreatic bicarbonate secretion; the sodium bicarbonate cotransporter (NBC); cystic fibrosis transmembrane conductance regulator (CFTR); regulators of the ion channels and ion transporters involved in secretion

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Advances in Cell Proliferation, Senescence and Apoptosis

edited by

Chuanxi Cai

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4847 | Submission Open

Keywords: biological molecules; cell proliferation; senescence; apoptosis; human diseases

(This special issue belongs to the Section Molecular Biology)

CNS Injuries: 2nd Edition

edited by

Sudhanshu Raikwar

submission deadline 20 Sep 2025 | 1 articles | Viewed by 4787 | Submission Open

Keywords: stroke; TBI; brain edema; SCI; spinal cord edema; neuroinflammation; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Application of Natural Products in Biomedicine and Pharmacotherapy: 2nd Edition

edited by

George Miloshev

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4754 | Submission Open

Keywords: natural products; biomedicine; genotoxicity; epigenetics; aging

(This special issue belongs to the Section Molecular Pharmacology)

Cellular and Molecular Biology in the Compromised Neonate

edited by

Tim G. A. M. Wolfs

submission deadline 20 Sep 2025 | 1 articles | Viewed by 4752 | Submission Open

Keywords: compromised neonate; infections; placental dysfunction; disrupted oxygen supply; molecular and cellular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Melanoma and Skin Cancers: 2nd Edition

edited by

Domenico Mallardo

Debora Basile

and Maria Grazia Vitale

submission deadline 20 Sep 2025 | 5 articles | Viewed by 4695 | Submission Open

Keywords: melanoma; immunotherapy; biomarkers; translational research; drug repurposing; clinical outcome; prognostic markers; predictive markers; combination immunotherapy

(This special issue belongs to the Section Molecular Oncology)

New Advances in Stem Cells in Human Health and Diseases

edited by

Elisaveta N. Voynova

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4638 | Submission Open

Keywords: stem cells biology; iPSCs; hESC

(This special issue belongs to the Section Molecular Biology)

Bacterial Adaptation Strategies to the Host: From Acute, Aggressive to Chronic, Dormant Infections, 2nd Edition

edited by

Bettina Löffler

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4612 | Submission Open

Keywords: dormancy; phenotype switching; bacterial stress; survival strategies; persisters; resuscitation; starvation; cell cycle arrest; ATP homeostasis

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms and Therapies for Metabolic-Associated Fatty Liver Diseases

edited by Yi-Ming Arthur Chen

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4583 | Submission Open

Keywords: metabolic-associated fatty liver disease; MAFLD; metabolic dysfunction-associated steatohepatitis; MASH; molecular mechanism; genetic polymorphism; individualized medicine; prevention; new drug development; health supplements; diagnosis; epidemiology; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Compounds for Counteracting GI and Liver Diseases

edited by

Daniela Gabbia

and

Raquel Abalo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4553 | Submission Open

Keywords: natural compounds; gastrointestinal diseases; liver diseases; pharmacological potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bioactive Compounds and Their Anticancer Effects

edited by

Ji Hoon Jung

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4481 | Submission Open

Keywords: ferroptosis; natural compounds; bioactive compounds; p53; anti-cancer drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Emerging Advances in Cancer Biomarkers: Machine Learning, Radiomics, Genomics, and More

edited by

Hung-Yu Lin

and

Pei-Yi Chu

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4392 | Submission Open

Keywords: cancers; biomarkers; precision medicine; artificial intelligence; machine learning; radiomics; genomics; radiogenomics; multi-omics; pharmacogenetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Displaying special issue 2101-2150 on page 43 of 70.

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