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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms and Treatment of Cardiovascular Diseases
edited by
submission deadline 20 Oct 2024 | 3 articles | Viewed by 2476 | Submission Open
Keywords: cardiovascular diseases; molecular pathology; microRNAs; diabetes; cardiovascular complications of diabetes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Proteases and Protease Inhibitors in the Immune System
edited by
submission deadline 20 Oct 2024 | 3 articles | Viewed by 2437 | Submission Open
Keywords: serine protease; cleavage specificity; mast cell; neutrophilic granulocyte; cytotoxic T cell; NK cell; immune regulation; toxin; tissue homeostasis; angiotensin; cytokines; complement system; coagulation system
(This special issue belongs to the Section Molecular Immunology)
Influenza Viruses: Infection and Genomics
edited by
submission deadline 20 Oct 2024 | 2 articles | Viewed by 2355 | Submission Open
Keywords: influenza viruses; avian influenza; virus replication; infection; convergent evolution; restriction factors
(This special issue belongs to the Section Molecular Immunology)
Molecular Research of Selenocysteine in Selenoproteins
edited by
submission deadline 20 Oct 2024 | 2 articles | Viewed by 2300 | Submission Open
Keywords: selenocysteine; selenoproteins; selenium; oxidoreductase; antioxidant; suppression
(This special issue belongs to the Section Biochemistry)
Exploring Cytochromes P450: Drug Metabolism, Endogenous Metabolism, and Human Health
edited by Ewa Bromek, and Wojciech Kuban
submission deadline 20 Oct 2024 | 3 articles | Viewed by 2159 | Submission Open
Keywords: cytochrome P450; drug metabolism; endogenous substrate metabolism; liver metabolism; brain metabolism
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Physiopathology of Connective Tissue: Regenerative Perspective
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 2111 | Submission Open
Keywords: connective tissue; physiopathology; molecular medicine; regenerative medicine; healing; collagen; hyaluronan
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Research on Omics of Microorganisms submission deadline 20 Oct 2024 | 2 articles | Viewed by 2035 | Submission Open
Keywords: microbial metabolism; genomics; transcriptomics; proteomics; metabolomics; metabonomics; bioinformatics
(This special issue belongs to the Section Molecular Microbiology)
Molecular Insight into Gestational Diabetes Mellitus
edited by Marcin Trojnar and
submission deadline 20 Oct 2024 | 2 articles | Viewed by 1956 | Submission Open
Keywords: gestational diabetes mellitus; biomarkers; maternal risk factors; fetal programming; maternal programming; insulin resistance; endothelial dysfunction; inflammation; oxidative stress; placental growth factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondrial and Energy Metabolic Function in Heart and Skeletal Muscle
edited by Yoshitake Cho
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1855 | Submission Open
Keywords: heart; skeletal muscle; metabolism; glucose; mitochondria; metabolic disorder
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Mechanisms and Therapeutic Strategies of Inflammatory Pain
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1807 | Submission Open
Keywords: inflammation; inflammatory pain; molecular mechanism; central sensitization
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanomedicine Advances in the Treatment of Chronic Inflammation submission deadline 20 Oct 2024 | 2 articles | Viewed by 1767 | Submission Open
(This special issue belongs to the Section Molecular Nanoscience)
Immunotherapy: A New Perspective in Cancer Treatment
edited by Ivana Marinović-Terzić
submission deadline 20 Oct 2024 | 3 articles | Viewed by 1727 | Submission Open
Keywords: immunotherapy; cancer treatment; breakthroughs; oncology; checkpoint inhibitors; CAR-T cell therapy; therapeutic vaccines; clinical trials; accessible healthcare
(This special issue belongs to the Section Molecular Immunology)
New Insights into Proteomics and Applications in Molecular Diagnostics and Systems Biology
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1627 | Submission Open
Keywords: mass spectrometry; liquid chromatography; tandem mass spectrometry (MS/MS); quantitative proteomics; shotgun proteomics; label-free quantification; post-translational modifications; protein– protein interactions; proteogenomics; single-cell proteomics; data analysis; bioinformatics; functional proteomics; phosphoproteomics; glycoproteomics; biomarker discovery; top– down proteomics; clinical applications; disease proteomics; systems biology
(This special issue belongs to the Section Molecular Informatics)
Arteriogenesis, Angiogenesis and Vascular Remodeling 2.0
edited by and
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1595 | Submission Open
Keywords: arteriogenesis; angiogenesis; collateral formation; peripheral arterial disease; vascular remodeling; atherosclerosis; restenosis; intimal hyperplasia; vein grafting; cardiovascular diseases; cell and gene therapy; critical limb ischemia; therapeutic angiogenesis; collateral circulation; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Evolving Ribosome Concept
edited by
submission deadline 20 Oct 2024 | 2 articles | Viewed by 1560 | Submission Open
Keywords: specialised ribosomes; ribosome heterogeneity; differential rRNA modification; ribosomal protein paralog genes; variation ribosome composition
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Pathology Research on Pregnant Uterus, Uterine Infections and Diseases
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1554 | Submission Open
Keywords: pregnancy; labor; delivery; uterine infection; endometritis; endometriosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in AI and Machine Learning for the Analysis of -Omics and Complex Molecular Data
edited by David P Kreil and Aleksandra Gruca
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1519 | Submission Open
Keywords: computational biology; bioinformatics; machine learning/AI; high-throughput data analysis; multi-omics; genomics; transcriptomics; proteomics; metabolomics; regulation mechanisms; pathway analysis (regulation; signaling; and metabolic); molecular pathology; complex diseases (cancer; cardiovascular; autoimmune; ageing-related; etc.); biomarkers; functional prediction/annotation; benchmarking
(This special issue belongs to the Section Molecular Informatics)
Colorectal Cancers: An Update on Their Molecular Pathology and Therapy
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1486 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Therapeutic Approaches to Osteoarthritis
edited by
submission deadline 20 Oct 2024 | 3 articles | Viewed by 1461 | Submission Open
Keywords: mode of action; molecular mechanisms; pathogenesis; drug delivery; disease-modifying drug; translational research; cell therapy; regenerative medicine
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Interactions between Plants and Pests
edited by
submission deadline 20 Oct 2024 | 3 articles | Viewed by 1441 | Submission Open
Keywords: immunity molecular mechanisms; plant immunity; plant pests; root microbiome; plant defense signaling; defense metabolites; plant defense tolerance; plant receptors; effectors; elicitors; phytophagous arthropod co-evolution; effectors
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research of Gastrointestinal Disease 2.0 submission deadline 20 Oct 2024 | 2 articles | Viewed by 1401 | Submission Open
Keywords: gastrointestinal health; gastrointestinal disorders; gastrointestinal disease; gastrointestinal homeostasis; molecular targets; mechanisms; pathways; molecular markers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Implication of Nanoparticles in Cancer Therapy Research 2.0 submission deadline 20 Oct 2024 | 1 articles | Viewed by 1388 | Submission Open
Keywords: nanotechnology; nanoparticles; nanocarriers; drug delivery; cancer therapy
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Advances in Circadian Rhythm and Metabolism
edited by Olga Cela and Rosella Scrima
submission deadline 20 Oct 2024 | 2 articles | Viewed by 1378 | Submission Open
Keywords: circadian rhythms; metabolism; clock genes; protein processing/post-translational modifications; chronomedicine
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Alzheimer’s Disease and Other Dementias—Molecular Therapeutic Approaches submission deadline 20 Oct 2024 | 1 articles | Viewed by 1288 | Submission Open
Keywords: dementia; prevention of dementia; treatment of dementia; amyloid tangles; tauopathies; mild cognitive impairment; neurodegenerative pathways; toxic elements inducing dementia; drug screening; drug design; cell or organelle therapy; device development; neurodegeneration; neuroinflammation
(This special issue belongs to the Section Molecular Neurobiology)
Current Trends in Molecular Mechanisms of Virulence in Human Pathogenic Bacteria
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1275 | Submission Open
Keywords: mechanisms of virulence; gene regulatory networks; host– pathogen interaction; gene regulation; virulence factors; high-throughput technologies
(This special issue belongs to the Section Molecular Microbiology)
Pathogenesis and Immunology of Cytomegalovirus
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1225 | Submission Open
Keywords: cytomegalovirus (CMV); human herpes virus 5 (HHV5); congenital CMV; fetus; acquired immunodeficiency syndrome (AIDS); CMV polyradiculomyelopathy (PRAM); inflammaging; immunosenescence; pathogenesis; immunology
(This special issue belongs to the Section Molecular Microbiology)
Mitochondrial Footprint in Neurological Pathology submission deadline 20 Oct 2024 | 1 articles | Viewed by 1142 | Submission Open
Keywords: neurological disorders; mitochondrial bioenergetics; mitochondrial dynamics; immunometabolism; biomarkers; mitochondrial medicine
(This special issue belongs to the Section Molecular Neurobiology)
Antiviral Activity of Lectins
edited by Yuichiro Sato
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1128 | Submission Open
Keywords: lectin; carbohydrate-binding specificity; virus; antiviral activity; glycan
(This special issue belongs to the Section Molecular Pharmacology)
Editorial Board Members’ Collection Series: “Neuroinflammation” submission deadline 20 Oct 2024 | 1 articles | Viewed by 1069 | Submission Open
Keywords: neuroinflammation; amyotrophic lateral sclerosis; multiple sclerosis; Parkinson's disease; Alzheimer's disease; ataxias; traumatic brain injury; spinal cord injury
(This special issue belongs to the Section Molecular Immunology)
Pesticide Exposure and Toxicity 2.0
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1068 | Submission Open
Keywords: multiple pesticides; cumulative assessment; probabilistic assessment; mechanisms of molecular toxicology
(This special issue belongs to the Section Molecular Toxicology)
Advances in Molecular Dynamics Simulation of Chemical and Biomedical Systems submission deadline 20 Oct 2024 | 2 articles | Viewed by 1054 | Submission Open
Keywords: molecular dynamics simulation; chemical and biomedical systems; molecular-level processes; protein structures; drug binding mechanisms; biomolecular behavior; drug design; biomedicine materials
(This special issue belongs to the Section Molecular Informatics)
Unlocking the Future of Muscle Disease Treatment: Advancements in Gene Therapy, Antisense Therapeutics and Cutting-Edge Pharmacological Strategies
edited by and Alberto Malerba
submission deadline 20 Oct 2024 | 2 articles | Viewed by 1042 | Submission Open
Keywords: muscle disease; antisense therapeutics; gene therapy; pharmacological approach; bioinformatic tools; cellular models; animal models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Short and Long-Term Profound Acid Inhibition: Indications and Concerns
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 1012 | Submission Open
Keywords: gastric acid; gastric cancer; gastric neuroendocrine tumours; gastric juice; gastrin; Helicobacter pylori; oesophageal reflux disease; pepsin; peptic ulcer disease; gastric cancer histology and classification; rebound acid hypersecretion
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Application and Latest Progress of Bioinformatics in Drug Discovery
edited by Alfonso Trezza
submission deadline 20 Oct 2024 | 1 articles | Viewed by 977 | Submission Open
Keywords: molecular dynamics and docking simulation; molecular modeling; target and drug discovery; artificial intelligence; big data
(This special issue belongs to the Section Molecular Informatics)
TRP Channels in Pain and Inflammation 2.0 submission deadline 20 Oct 2024 | 1 articles | Viewed by 959 | Submission Open
Keywords: TRP channels; “ thermoTRP” channels; neuropathic pain; inflammatory pain; cancer pain; pruritic skin iseases; itch; neurogenic inflammation; migraine
(This special issue belongs to the Section Molecular Immunology)
Advances in Structure–Function Investigations of Viruses
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 958 | Submission Open
Keywords: structure; assembly; viruses; crystallography; spectroscopy; computer modeling
(This special issue belongs to the Section Molecular Biophysics)
New Insights into the Molecular Mechanisms of Chronic Pain submission deadline 20 Oct 2024 | 1 articles | Viewed by 942 | Submission Open
Keywords: dorsal root ganglia; spinal cord; brain; opioids; monoamines; GABA; anxiety; depression; cognition; optogenetics; electrophysiology; behavior; glial cells
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Physiological and Biochemical Research on Forest Plants to Improve Abiotic Stress Tolerance submission deadline 20 Oct 2024 | 1 articles | Viewed by 925 | Submission Open
Keywords: forests plants; abiotic stress; ecophysiology; genetic analyses; dendrochronology; biochemical analyses
(This special issue belongs to the Section Molecular Plant Sciences)
The Application of Nanoparticles in Biomedicine
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 774 | Submission Open
Keywords: nanoparticle; nanomaterial; biomedicine; imaging; therapy; contrast agent; therapeutic agent
(This special issue belongs to the Section Molecular Nanoscience)
The Human Fetal Membranes: A Versatile Tissue Important for Pregnancy Health and Regenerative Therapies
edited by Claire E. Kendal-Wright and Lauren Richardson
submission deadline 20 Oct 2024 | 1 articles | Viewed by 753 | Submission Open
Keywords: fetal membranes; tissue strength; inflammation; parturition; preterm premmature rupture of the membrane (PPROM); infection; stem cells; regenerative surgery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Vascular Biology: From Pathophysiology to Therapy
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 745 | Submission Open
Keywords: vascular biology; angiogenesis; atherosclerosis; thrombosis; vasculitis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Atherosclerosis and Vascular Endothelial Cells
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 705 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Melanoma Therapy
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 676 | Submission Open
Keywords: melanoma; anti-cancer; immunotherapy; targeted therapy; signaling pathway; Polyphenolic compounds; cannabinoids; pharmacotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on the Pancreatic Cancer submission deadline 20 Oct 2024 | Viewed by 628 | Submission Open
Keywords: PDAC; biomarker; metastasis; chemoresistance
(This special issue belongs to the Section Molecular Oncology)
Strategies to Fight Metabolic Diseases submission deadline 20 Oct 2024 | 1 articles | Viewed by 617 | Submission Open
Keywords: metabolic diseases; RNA interference (RNAi) therapy; metabolic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Tree Plant Genomics: Towards a Future with Evolutionary Significance and Breeding Applications
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 608 | Submission Open
Keywords: tree plant; genomics; breeding
(This special issue belongs to the Section Molecular Plant Sciences)
Regulation and Activation of Immune Cells through the Mitochondria
edited by
submission deadline 20 Oct 2024 | Viewed by 598 | Submission Open
Keywords: mitophagy in immune cells; autophagy and mitochondria in immune cells; fission and fusion of mitochondria in immune cells; oxphos and mitochondria in immune cells; glycolysis and mitochondria in immune cells; tissue residency of immune cells and their mitochondria; tumor infiltrating lymphocytes and their mitochondria; mitochondria in inflammation
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Nanotoxicology
edited by
submission deadline 20 Oct 2024 | 1 articles | Viewed by 581 | Submission Open
Keywords: nanotoxicology; nanodrugs; nanoparticles; adverse drug reactions; cytotoxicity
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Advance in Cheminformatics and Nanoinformatics: Pioneering Solutions for Modern Challenges submission deadline 20 Oct 2024 | 1 articles | Viewed by 445 | Submission Open
Keywords: cheminformatics; nanoinformatics; precision toxicology; personalized medicine; precision agriculture; COVID-19; drug discovery; computational toxicology; nanosafety; nano-QSAR; deep learning; artificial intelligence; nanotoxicology; nanomedicine; data mining; big data; QSAR/QSPR; in silico modeling; web applications; predictive toxicogenomics; biokinetics; risk assessment; software tools
(This special issue belongs to the Section Molecular Informatics)
Personalized Nanomedicine in Oncology
edited by Sajid Ali
submission deadline 20 Oct 2024 | Viewed by 388 | Submission Open
Keywords: drug/gene delivery; biomaterials; stimuli-responsive systems; lipid– polymer nanoparticles; lipodendriplexes; dual delivery; inorganic nanoparticles; targeted delivery system
(This special issue belongs to the Section Molecular Nanoscience)
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