The Role of Dietary Fibre, Nutrition in Gastrointestinal Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 1 March 2026 | Viewed by 32
Special Issue Editor
Special Issue Information
Dear Colleagues,
An adequate diet plays a key role not only in maintaining digestive health, but also in preventing intestinal diseases and supporting their treatment. Dietary fibre has a beneficial effect on the intestinal microbiome by providing food for fermenting bacteria that produce short-chain fatty acids, such as butyrate. These metabolites promote mucosal integrity and modulate immune system function through various molecular pathways. In inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, intestinal dysbiosis, and impaired intestinal homeostasis are often observed. In this case, the role of fibre becomes even more important, especially since its fermentation products can affect gene expression and inflammatory signalling at the cellular level.
A balanced diet that provides adequate nutrients, particularly a variety of fibre fractions, can alleviate symptoms and promote the restoration of intestinal barrier integrity. Interactions involve complex mechanisms such as modulation of oxidative stress, cytokine regulation, and even epigenetic changes. Understanding the interactions between dietary fibre, the gut microbiome, and gastrointestinal disease is crucial to developing effective nutritional strategies to support the therapeutic process, especially in the context of molecular medicine.
Dr. Sara Jarmakiewicz-Czaja
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- dietary fibre
- gut microbiome
- gastrointestinal disease
- inflammatory bowel disease
- nutrients
- nutrition
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
