Exploring Molecular Insights in Oral Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 8
Special Issue Editors
Interests: signaling pathways; saliva; oral biocompatibility; periodontal disease; burns; cancer cells metabolism; metabolic reprogramming; autoimmune diseases; oral health; physiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
According to the World Dental Federation (FDI), "oral health is multi-faceted and includes the ability to speak, smile, smell, taste, touch, chew, swallow and convey a range of emotions through facial expressions with confidence and without pain, discomfort and disease of the craniofacial complex (head, face, and oral cavity)." Decades of research have demonstrated the bidirectional relationship between oral and systemic health. Oral diseases affect not only the teeth and oral tissues but also produce general effects, impacting the emotional and psychological state of patients, and the overall quality of life. Studies have highlighted the key role that molecular events, signaling pathways and cellular metabolism play in oral health as well as in the development of oral diseases or their treatment. Moreover, dental treatments and restorations are essential to restore the morphology and function of the teeth and craniofacial structures; therefore, it is of utter importance to study the biocompatibility and molecular-level interactions of novel materials with the oral environment.
This Special Issue invites the submission of original articles, reviews, case reports as well as clinical- and pure-model studies that include biomolecular experiments that display the current advances in the field of molecular biology and biochemistry related to oral health, diseases and treatments, including dental restorations, splints and prostheses. Studies on the molecular physiology of the oral cavity, the signaling pathways involved in the development of oral pathologies and targeted therapies are also welcome, as well as manuscripts that provide any additional information that provide additional information offering deeper understanding and new perspectives on the molecular landscape of oral health and diseases.
Dr. Iulia-Ioana Stanescu-Spinu
Dr. Tudor Claudiu Spînu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oral health
- saliva
- oral diseases
- molecular insights
- molecular targets
- oral cavity physiology
- wound healing
- oral microbiome
- oral biocompatibility
- material interactions
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