The Impact of Circulating Biomarkers and Metabolites on Cardiometabolic Disease and Cancer: New Insights and Therapeutic Opportunities
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 20
Special Issue Editors
Interests: metabolomics; lipidomics; amino acids and lipid metabolism; metabolic syndrome; cardiometabolic risk; cardio-vascular disease; obesity; fatty liver disease
Special Issues, Collections and Topics in MDPI journals
Interests: cardiometabolic risk; cardiometabolic disease; biomarkers; endothelial function; sphingolipids
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Circulating biomarkers and metabolites, such as amino acids and lipids, regulate biological processes associated with normal cell function and metabolism. In particular, changes in lipid species and amino acid profiles can have a significant role in cell function and regulation, anti-oxidant processes, the immune system, and inflammatory responses. We invite investigators to contribute either original research or review articles accordingly, within the aims of this special issue (clinical or model studies will not suitable, but clinical or pure model submissions with biomolecular experiments are welcomed), focusing on the role and mechanisms of significant circulating biomarkers and cellular pathways which drive or take part in the onset and development of metabolic diseases (i.e., obesity, diabetes, non-alcoholic fatty liver disease) cardiovascular disease (i.e., atherosclerosis, hypertension, coronary artery diseases) and tumorigenses. Subtopics may include, but are not limited to, the following issues:
- Metabolomic and lipidomic approaches and metabolic disease;
- Assessment of biochemical and molecular biomarkers related to cardiometabolic risk and prevention;
- Lipids and amino acids profiles in cardiometabolic syndrome;
- Insulin and glucose metabolism and cardiometabolic disease;
- Metabolomic evaluation and cancer biomarkers on tumorigenesis.
Dr. Melania Gaggini
Dr. Cristina Vassalle
Guest Editors
Manuscript Submission Information
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Keywords
- lipidomic
- metabolomic
- lipotoxicity
- oxidative stress
- amino acids
- metabolic disease
- cardiovascular risk
- tumorigenesis
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