Molecular Mechanisms and Therapeutic Strategies for Oral Mucosal Diseases: From Radiotherapy-Induced Damage to Other Pathologies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 28
Special Issue Editor
Interests: oral medicine; estomatologia; oral mucosal diseases; treatment and preventive methods for salivary changes induced by head and neck radiotherapy; low level laser therapy in oral mucosal diseases; treatment of ulcerated lesions of the oral mucosa
Special Issue Information
Dear Colleagues,
Oral mucosal diseases comprise a wide spectrum of conditions, including drug-induced mucosal damage, radiotherapy- or chemotherapy-related injuries, inflammatory, autoimmune, and infectious disorders, benign neoplasms, and potentially malignant and malignant lesions. Although significant progress has been made in their clinical management, the molecular and cellular mechanisms underlying many of these disorders remain incompletely understood. This gap hinders the development of targeted preventive and therapeutic strategies.
This Special Issue of the International Journal of Molecular Sciences aims to collect high-quality original research and comprehensive review articles addressing the molecular basis of oral mucosal diseases and exploring innovative therapeutic approaches. We particularly welcome studies elucidating signaling pathways, oxidative stress, immune responses, and microbiota interactions, as well as investigations into regenerative mechanisms and translational aspects of emerging therapies—such as photobiomodulation, nanomedicine, tissue engineering, and immunotherapy. By integrating basic, translational, and clinical perspectives, this Issue seeks to advance mechanistic understanding, stimulate interdisciplinary collaboration, and promote novel strategies to improve the prevention and treatment of oral mucosal disorders.
Prof. Dr. Fernanda Gonçalves Salum
Guest Editor
Manuscript Submission Information
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Keywords
- oral mucosal diseases
- drug-induced oral lesions
- radiotherapy- and chemotherapy-induced oral disorders
- targeted therapy- and immunotherapy-induced stomatitis
- oxidative stress and inflammation
- oral microbiome and immunity
- nanomedicine and biomaterials
- photobiomodulation and photodynamic therapy
- oral potentially malignant disorders
- oral oncology
- immune modulation
- tissue regeneration and repair
- translational research
- investigational therapy
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