Lung Cancer: Molecular Basis and Treatment Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 October 2026
Special Issue Editor
Special Issue Information
Dear Colleagues,
Lung cancer remains a leading cause of cancer-related mortality worldwide, characterized by profound genetic heterogeneity and complex molecular landscapes. Advances in high-throughput sequencing and multi-omics integration have revolutionized our understanding of the oncogenic drivers and resistance mechanisms underlying non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC).
This Special Issue will highlight the molecular mechanisms governing lung cancer initiation, progression, and metastasis. We invite original research and comprehensive reviews focusing on novel molecular targets, the role of the tumor microenvironment, and the application of precision medicine. Key areas of interest include the discovery of predictive biomarkers, the impact of epigenetic modifications, and the development of innovative therapeutic strategies, such as targeted small molecules and immunotherapies. By bridging the gap between basic molecular biology and clinical application, this Special Issue will provide insights on overcoming therapeutic resistance and improving patient outcomes.
We look forward to receiving your contributions.
Dr. Hamada A.A. Noreldeen
Guest Editor
Manuscript Submission Information
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Keywords
- adenocarcinoma
- oncogenic drivers
- precision oncology
- signal transduction
- tumor microenvironment
- targeted therapy
- resistance mechanisms
- epigenetics
- biomarker discovery
- immunotherapy
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