Application of Nanomedicine in Cancer Targeting and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".
Deadline for manuscript submissions: 20 August 2026 | Viewed by 717
Special Issue Editor
Interests: nuclear pore complex; AFM; nanomedicine; cancer biology; virology; tumor immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer remains a formidable global health challenge, demanding innovative approaches to improve diagnosis precision and therapeutic outcomes. Nanomedicine has emerged as a transformative frontier, leveraging engineered materials at the nanoscale to overcome critical limitations of conventional methods—such as poor drug solubility, non-specific biodistribution, and inadequate therapeutic monitoring. Despite promising preclinical advances, translating these breakthroughs into clinical practice faces hurdles including biological barriers, manufacturing scalability, and patient-specific tumor heterogeneity.
This Special Issue seeks to accelerate progress by highlighting high-impact studies that bridge nanotechnology innovation with tangible clinical solutions. We invite contributions addressing both the promise and practical translation of nanomedicine in oncology, with emphasis on the following:
- Multifunctional Nanoplatforms: Integrating therapy and real-time diagnostics (e.g., theranostics) for precision cancer management.
- Biomarker-Driven Strategies: Nanosensors or targeted systems enabling early detection, predictive biomarker analysis, or therapy personalization.
- Next-Generation Nanoformulations: Smart carriers (stimuli-responsive, ligand-guided) enhancing tumor targeting, drug stability, and therapeutic efficacy while reducing toxicity.
- Translational Validation: Robust preclinical (in vivo) and clinical assessments (patient-derived samples) demonstrating safety, biodistribution, and efficacy.
- Advanced Nanoimaging: characterization of conformational dynamics of nanomedicines at nanoscale level (e.g., NMR/raman/AFM and HS-AFM), high-sensitivity cancer imaging, margin delineation, or treatment monitoring (e.g., MRI/PET/fluorescence).
We welcome original research and reviews emphasizing:
- Innovative designs addressing biological/clinical barriers
- Mechanistic insights into tumor targeting and drug release
- Scalable, clinically adaptable platforms
- Interdisciplinary approaches with clear therapeutic impact
Why Contribute?
This Special Issue will spotlight strategies poised to overcome current translational gaps. Your work will reach chemists, material scientists, pharmacologists, and clinicians dedicated to advancing effective, patient-centered cancer nanomedicine.
Dr. Kee Siang Lim
Guest Editor
Manuscript Submission Information
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Keywords
- nanomedicine
- nanoimaging/bioimaging
- cancer biology
- theranostics
- translational nanomedicine
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