Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 12
Special Issue Editors
Interests: neurodegenerative disorders; Alzheimer’s disease; Parkinson’s disease; behavioral pharmacology; neuropharmacology; antioxidants; neuroinflammation; pharmacognosy; medicinal herbs
Interests: biochips; pharmacology; traditional Chinese medicine; medicinal herbs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammation is a complex biological response to harmful stimuli such as pathogens, damaged cells, or irritants, and it plays a crucial role in the development and progression of various chronic diseases, including cardiovascular disorders, arthritis, cancer, diabetes, and neurodegenerative conditions. While inflammation is essential for host defense and tissue repair, prolonged or excessive inflammatory responses can contribute to disease pathogenesis.
Increasing attention has been directed toward the anti-inflammatory properties and potential health benefits of plants. Numerous studies have demonstrated that traditional medicinal plants exhibit significant anti-inflammatory effects. These plants act through multiple mechanisms, such as inhibiting pro-inflammatory cytokines, modulating signaling pathways (e.g., MAPKs, NF-κB, NLRP3, inflammasome) and suppressing oxidative stress. Their incorporation into diets or therapeutic regimens offers a promising strategy for maintaining physiological balance and preventing inflammation-related disorders. Among the bioactive phytochemicals of plants, phenolic compounds—including flavonoids, phenolic acids, tannins, and lignans—are particularly noteworthy. Advanced analytical techniques, including high-performance liquid chromatography (HPLC) and mass spectrometry (MS), have enabled the precise characterization of phenolic content in different plant species. Correlations between specific phenolic profiles and anti-inflammatory activities have been increasingly established, providing a scientific basis for the development of functional foods and plant-based therapeutics.
I am pleased to invite you to contribute this Special Issue of the International Journal of Molecular Sciences (IJMS), titled “Current Research on Phenolic Profiles and Anti-inflammatory Activities of Plants”. This Special Issue aims to showcase a curated collection of cutting-edge research and contemporary review articles that explore the interplay between plant phenolic composition and anti-inflammatory efficacy to offer promising avenues for the development of natural anti-inflammatory agents and guide their clinical applications from plants. Continued research is essential to fully understand their bioavailability, metabolism, and long-term efficacy in clinical settings. I look forward to receiving your contributions.
Prof. Dr. Chi-Rei Rei Wu
Prof. Dr. Li-Wei Lin
Guest Editors
Manuscript Submission Information
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Keywords
- plants
- phenolic profiles
- inflammation
- cardiovascular disorders
- cancer
- diabetes
- neurodegenerative disorders
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