Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 290
Special Issue Editor
Interests: endocrine oncology; theragnostics; molecular targeted radiotherapy; Lu-177 dotatate; Lu-177 PSMA; thyroid cancer; prostate cancer; neuroendocrine tumors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Thyroid cancer and thyroid dysfunctions represent up to 2% of human disorders and a third of endocrine disorders. The field of thyroid disorders in endocrinology is growing, extending to thyroid dysfunctions related to new targeted and therapy-related immune-checkpoint inhibitors. Although there have been no significant changes in the prevalence and incidence of thyroid cancer, nor in its overall survival rate, recent progress in basic science, clinical studies, and translational research on this disease has led to new perspectives and improved understanding of thyroid disorders and thyroid oncogenesis.
The main objective of this Special Issue is to present original research on the molecular biology of thyroid cancer and thyroid dysfunctions. We hope to highlight new data on molecular pathways and metabolic characteristics that might advance our understanding of the development of thyroid cancer and thyroid dysfunction, paving the way for the discovery of new diagnostic options and new targeted or combined therapies.
The topics of this Special Issue include, but are not limited to, the following:
- Key biological processes such as the cell cycle, DNA repair, apoptosis, autophagy, angiogenesis, invasion and metastasis, and signaling pathways.
- Molecular thyroid pathology.
- The thyroid cancer microenvironment.
- The metabolic pathways involved in thyroid cancer.
- Cancer epidemiology and prevention.
- Cancer biomarkers: screening, diagnosis, treatment response, and prognosis.
- Cancer therapy: target discovery, drug design, resistance, targeted therapy, theranostics, and personalized medicine.
- Translational cancer research.
- High-throughput technologies: genomics, epigenomics, proteomics, metabolomics, microarray, next-generation sequencing, and other omics technologies for thyroid dysfunctions.
- Genomic and proteomic databases and their applications.
Dr. Vija Lavinia
Guest Editor
Manuscript Submission Information
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Keywords
- animal models
- apoptosis
- autophagy
- cancer biomarker
- cancer epidemiology
- cancer prevention
- cancer screening
- cholesterol metabolism
- clinical trial
- DNA repair
- epigenomics
- genome instability
- genomic database
- genomics
- invasion
- metabolomics
- metastasis
- methylation
- microarray
- microRNA
- molecular diagnostics
- molecular tumor pathology
- next-generation sequencing
- noncoding RNA
- omics
- personalized medicine
- prognosis
- proteomics
- radionuclide therapy
- signaling pathway
- SNP genotyping
- targeted therapy
- theranostics
- thyroid cancer
- hyperthyroidism
- therapeutic targets
- translational cancer research
- treatment response
- tumor microenvironment
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