Pregnancy-Related Complications: Molecular Pathogenesis and Therapeutic Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 27
Special Issue Editor
Interests: molecular pathogenesis of hypertensive disorders in pregnancy; aquaporins in pregnancy complications; oxidative stress and mitochondrial dysfunction in normal and preeclamptic pregnancies; maternal-fetal transport mechanisms; uric acid as a molecular marker; extracellular vesicles; fetal programming of chronic diseases; translational approaches in pregnancy, including aspirin use; application of artificial intelligence in the study and prediction of pregnancy complications
Special Issue Information
Dear Colleagues,
Pregnancy-related complications remain a major global health concern, affecting maternal and fetal outcomes and increasing the risk of long-term morbidity. Among the most common and clinically relevant conditions are hypertensive disorders (such as preeclampsia and eclampsia), gestational diabetes, intrauterine growth restriction, preterm birth, placental insufficiency, infections during pregnancy, and amniotic fluid abnormalities. Despite advances in obstetric care, the molecular mechanisms underlying these complications are still not fully understood, limiting early diagnosis and effective interventions.
This Special Issue aims to gather innovative research addressing the molecular pathogenesis of pregnancy complications, with particular interest in the role of placental dysfunction, maternal-fetal communication, and novel molecular mediators such as extracellular vesicles. Contributions exploring emerging therapeutic strategies, biomarker discovery, and translational studies that bridge basic research and clinical practice are especially welcome. By integrating interdisciplinary approaches and advanced technologies, this collection seeks to deepen our understanding and improve outcomes in complicated pregnancies.
Dr. Alicia E. Damiano
Guest Editor
Manuscript Submission Information
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Keywords
- pregnancy-related complications
- placental dysfunction
- maternal-fetal communication
- extracellular vesicles
- translational research
- biomarkers
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