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Molecular Mechanisms of Thromboinflammation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 1

Special Issue Editor


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Guest Editor
Laboratory Medicine and Pathology Department, Group of Molecular Pathology and Pharmacogenetics, Biomedical Research Institute from Murcia (IMIB), Santa Lucía General University Hospital, 30202 Cartagena, Spain
Interests: cancer-associated thrombosis; thromboinflammation; biomarkers; molecular pathology; personalized medicine; oncology; hematology; immune system

Special Issue Information

Dear Colleagues,

Thromboinflammation—an intricate interplay between the coagulation cascade and immune response—is a key driver in the pathophysiology of numerous diseases. This Special Issue will explore the molecular and cellular mechanisms behind thromboinflammation across a broad spectrum of clinical contexts, including sepsis, ischemic stroke, autoimmune and inflammatory diseases, organ transplant rejection, and malignancies such as solid tumors and hematological disorders.

We welcome original research and comprehensive reviews investigating the immune–coagulation interface, signaling pathways promoting thromboinflammatory responses, platelet–leukocyte interactions, endothelial dysfunction, and the role of neutrophil extracellular traps (NETs). Studies identifying novel biomarkers or proposing translational approaches to target thromboinflammatory pathways are especially encouraged.

By encompassing both common and context-specific mechanisms, this Special Issue will advance our understanding of thromboinflammation and support the development of targeted therapeutic strategies across diverse disease settings.

Dr. Ana B. Arroyo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thromboinflammation
  • coagulation
  • inflammation
  • immune system
  • sepsis
  • stroke
  • autoimmune diseases
  • cancer
  • hematology
  • biomarkers
  • translational medicine

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Published Papers

This special issue is now open for submission.
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