Systems Approaches to Diabetic Complications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 7
Special Issue Editor
Interests: genomics; transcriptomics; diabetic nephropathy; kidney transplantation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diabetes and its complications, including microvascular (retinopathy, nephropathy, neuropathy) and macrovascular (cardiovascular disease, stroke, peripheral artery disease), represent complex, multifactorial challenges across molecular, cellular, and systemic levels. This Special Issue invites multidisciplinary contributions deploying system-level approaches to explore the complex interactions driving the onset and progression of these complications. We welcome submissions that incorporate omics technologies (genomics, transcriptomics, proteomics, metabolomics and pathomics), advanced cellular and animal models, computational modeling, and cutting-edge tools such as machine learning and artificial intelligence. These approaches can help elucidate the molecular networks connecting hyperglycemia, inflammation, endothelial dysfunction, fibrosis, and metabolic imbalance to disease pathogenesis and treatment response.
Original research, reviews, and commentaries focused on mechanistic insights, biomarker discovery, and translational applications are encouraged. We particularly value studies that bridge high-throughput data with experimental or clinical validation, supporting precision medicine in diabetic complications.
I am pleased to invite you to participate to this Special Issue.
Dr. Paola Pontrelli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- diabetes
- diabetic complications
- molecular mechanisms
- precision medicine
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