Immune Responses to Brain Viral Infections
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 20
Special Issue Editor
Special Issue Information
Dear Colleagues,
The brain is an important viral reservoir in humans. Viral infections are speculated to be associated with many brain diseases of unknown causes, such as Multiple Sclerosis (MS), and, recently, neurodegenerative diseases such as Alzheimer’s Disease (AD) and Parkinson’s Disease (PD). These speculations are partially supported by the fact that Amyloid beta, Tau protein, and Alpha Synuclein are all important innate immunity responders, and have gained more attention following the publication of our findings that Human Pegivirus has a significantly higher prevalence in the brains of PD patients compared to controls. Investigations exploring the interaction between immune responses (including innate immunity) and brain viral infections can help to better understand the viral neuropathogenesis that may lead to the development of a model or medicine for the infection.
This Special Issue focuses on recent studies aiming to advance our understanding of the interaction between immune responses and brain viral infections in MS and neurodegenerative diseases like AD and PD, as well as other brain diseases. Submissions are welcomed relating to clinical or pure models with biomolecular experiments, as well as those that explore the interaction between immune responses (including innate immunity) and brain viral infections, in addition to diagnostic biomarkers of brain viral infections.
Dr. Xin Dang
Guest Editor
Manuscript Submission Information
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Keywords
- immune response
- innate immunity
- viral neuropathogenesis
- viral biomarker
- AD
- PD
- neurodegenerative diseases
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