Molecular and Cellular Basis of Oral Immunology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 54
Special Issue Editor
Interests: clinical immunology; cancer immunity; oral mucosal disease; T cell receptor; oral microbiome; temporomandibular disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The oral cavity is the port of entry to the gastrointestinal and respiratory tracts, characterized by the juxtaposition of soft and hard tissues, and it is continuously subject to challenges by the external environment, such as foreign antigens or material. Given these constant challenges, the oral immune system plays a critical role in maintaining health, balancing robust defense against potential pathogens with tolerance to the commensal microbiome and ingested substances.
Understanding how this complex immune system functions within the unique oral environment at the molecular and cellular level is essential for advancing our knowledge of oral health and disease. This Special Issue, titled "Molecular and Cellular Basis of Oral Immunology", aims to showcase cutting-edge research exploring the cellular players, molecular mechanisms, signaling pathways, and intricate interactions that govern immune responses in the oral cavity. We invite submissions covering topics such as innate and adaptive immunity in oral tissues (mucosa, periodontium, salivary glands); immune cell phenotypes and functions unique to the oral site; the molecular recognition of oral pathogens and commensals; the role of immune cells and molecules in oral inflammation and tissue homeostasis; immunomodulation strategies; and the molecular and cellular underpinnings of immune-mediated oral diseases, including infections, autoimmune conditions, and oral cancers.
Dr. Kenichi Kumagai
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- oral immunology
- oral mucosa
- immune tolerance
- oral microbiome
- oral diseases
- periodontium
- innate immunity
- adaptive immunity
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