Autoimmune Diseases: From Molecular Mechanisms to Therapeutic Innovations
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editor
2. Department of Genetics, Biosciences Center, Federal University of Pernambuco, Recife Campus, Recife 50730-120, Brazil
Interests: immunity; lupus; arthritis; rheumatology; osteoporosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autoimmune diseases, where the immune system mistakenly attacks the body's tissues, affect millions of people worldwide. For a long time, their complexity puzzled scientists and doctors, but today, advances in molecular biology are helping us uncover their underlying mechanisms. We now understand that genetic, epigenetic, and environmental factors interact to trigger these conditions, and cutting-edge technologies, such as omics and bioinformatics, are uncovering new biomarkers and therapeutic targets, paving the way for personalized treatments. Moreover, innovative therapies—such as biologics and JAK inhibitors, as well as groundbreaking CAR-T cell therapy—are showing promising results in modulating immune responses with greater precision and safety. This Special Issue not only explores the molecular mechanisms behind autoimmune diseases but also discusses how these discoveries are being translated into real-world treatments that are already changing patients' lives. By integrating foundational research with therapeutic innovation, we highlight the potential to improve patient outcomes and move toward personalized management of these complex disorders, offering a better quality of life for patients.
Prof. Dr. Paula Sandrin-Garcia
Guest Editor
Manuscript Submission Information
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Keywords
- autoimmunity
- biological biomarkers
- personalized therapies
- biologics and JAK inhibitors
- CAR-T cell therapy
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