Intestinal Diseases and Gut Microbiota
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 60
Special Issue Editor
Interests: flavonoid; natural compounds; biological activity; anticancer activity; antioxidant activity; chalcone; multidrug-resistant pathogens; food science; antimicrobial agents; cytotoxicity assays; amyloid; Crohn’s disease; AIEC; biofilm
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Special Issue Information
Dear Colleagues,
The intestinal microbiota is a complex community of microorganisms inhabiting the human gastrointestinal tract, particularly the colon. It has metabolic, immunological and protective functions. Thus, maintaining the microbiota in the right quality-quantity ratio is important for health status. The phenomenon of dysbiosis, or an imbalance of this ratio, can be caused by various factors, i.e., antibiotic therapy, improper diet, stress, infections and chronic diseases. It contributes to increased intestinal permeability, chronic inflammation, weakened immunity and colonization with pathogens. This can in turn lead to the development of diseases such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), celiac disease, but also colorectal cancer (CRC).
This SI will consider both Original Articles on in vitro and in vivo studies, but also Reviews. Manuscripts on the relationship of the microbiota to autoimmune diseases, colorectal cancers, but also neurological diseases will be accepted. Those involving new therapies (e.g., fecal microbiota transplantation—FMT) and those based on prebiotics, probiotics, postbiotics and synbiotics will also be of interest. Any research on naturally derived compounds that are protective in nature against the composition, equilibrium and function of the gut microbiota will be a valuable addition to this SI. In addition, studies examining the effects of the microbiota on the gut-brain axis and thus on neurodegenerative diseases, mood, depression, anxiety, autism will also be welcome. We will include Manuscript, which will examine the modulating effect of the gut microbiota on immune mechanisms. In addition, molecular mechanisms of interaction of microbes belonging to the microbiota with host cells will be an interesting addition to this SI. Attractive, moreover, will be articles addressing the effects of metabolic mechanisms and their products on various types of modifications in the host, including effects on nervous system function. All researchers from around the world are welcome to send in their work.
Dr. Anna Duda-Madej
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiota
- dysbiosis
- natural compounds
- colorectal cancer
- neurological diseases
- autoimmune diseases
- probiotics
- gut-brain axis
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