Intestinal Diseases and Gut Microbiota
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 November 2025
Special Issue Editor
Interests: flavonoid; natural compounds; biological activity; anticancer activity; antioxidant activity; chalcone; multidrug-resistant pathogens; food science; antimicrobial agents; cytotoxicity assays; amyloid; Crohn’s disease; AIEC; biofilm
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
The intestinal microbiota is a complex community of microorganisms inhabiting the human gastrointestinal tract, particularly the colon. It has metabolic, immunological, and protective functions. Thus, maintaining the microbiota in the right quality–quantity ratio is important for health status. The phenomenon of dysbiosis, or an imbalance of this ratio, can be caused by various factors, i.e., antibiotic therapy, improper diet, stress, infections, and chronic diseases. These contribute to increased intestinal permeability, chronic inflammation, weakened immunity, and colonization with pathogens. This can in turn lead to the development of diseases such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), celiac disease, and colorectal cancer (CRC).
This Special Issue will consider reviews and original articles on in vitro and in vivo studies. Manuscripts on the relationship of the microbiota to autoimmune diseases, colorectal cancers, and neurological diseases are also welcome. Studies involving new therapies (e.g., fecal microbiota transplantation (FMT)) and those based on prebiotics, probiotics, postbiotics, and synbiotics are also of interest. Any research on naturally derived compounds that are naturally protective against composition, equilibrium, and function of the gut microbiota will be a valuable addition to this Special issue. In addition, studies examining the effects of the microbiota on the gut–brain axis and thus, on neurodegenerative diseases, mood, depression, anxiety, and autism are welcome as well. All researchers from around the world are welcome to submit their work.
We look forward to your submissions.
Dr. Anna Duda-Madej
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiota
- dysbiosis
- natural compounds
- colorectal cancer
- neurological diseases
- autoimmune diseases
- probiotics
- gut–brain axis.
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