Neurodegenerative Disease: Genetic Bases and Pathogenetic Mechanism
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 13
Special Issue Editor
Interests: rare diseases (especially hereditary spastic paraplegia) and sarcomas (e.g. clear cell sarcoma)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to highlight recent advances and novel discoveries in the field of neurodegenerative disorders. By exploring these conditions, researchers can uncover shared molecular and cellular pathways that may serve as promising targets for therapeutic intervention. There is a growing interest in utilizing different models, including in vitro systems, in vivo studies, and cutting-edge approaches (e.g., organoids), with an aim to gain deeper insights into disease mechanisms and to test potential treatments.
We welcome contributions from researchers across diverse disciplines and encourage the submission of original research articles and comprehensive reviews addressing the following themes:
- Rare diseases that cause motor disorders;
- Pathogenetic mechanisms in motor neuron diseases;
- Common mechanisms in neurodegenerative diseases and other conditions;
- Diseases of neurometabolic nature;
- Motor diseases of genetic nature;
- Epilepsies caused by or related to metabolic deficiencies;
- Models of metabolic motor disorders: in vivo and in vitro models and organoids;
- Genotype–phenotype correlation.
We look forward to your submissions.
Dr. Emanuele Panza
Guest Editor
Manuscript Submission Information
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Keywords
- neurodegenerative diseases
- molecular and cellular pathways
- pathogenetic mechanisms
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