Progress in Adipokines Research in Cardiovascular Health and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 171
Special Issue Editor
Interests: cardiac hypertrophy; heart failure; sodium hydrogen exchange (NHE1); adipokines; traditional Chinese medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the initial discovery of leptin in 1994, it is now recognized that adipose tissues function as endocrine organs which produce numerous bioactive cytokines generally referred to as adipokines, some examples of which are leptin, adiponectin, apelin, resistin, TNF-α, and interleukin-6, as well as others. While extensive ongoing research continues to unravel the extensive roles of adipocytes and adipocyte-derived adipokines in health and disease, there is now convincing evidence that various tissues, including components of the cardiovascular system, can produce a variety of adipokines while also expressing adipokine receptors and full signal transduction machinery. This implies that cardiovascular tissues, including heart and blood vessels, function not only as targets for the actions of circulating adipokines derived from adipocytes, but also that locally synthesized adipokines function in a paracrine or autocrine manner, resulting in modified cardiovascular function.
This Special Issue aims at elucidating the roles of adipokines in affecting cardiovascular function in health and disease, particularly emphasizing molecular and cellular mechanisms underlying these actions. Topics may include, but are not restricted to, the keywords indicated below, and both clinical and basic research studies or review articles are welcome. We welcome and look forward to your contributions to this Special Issue.
Prof. Dr. Morris Karmazyn
Guest Editor
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Keywords
- adipokine receptors and cell signalling
- adipokines and heart failure and hypertrophy
- adipokines and myocardial ischemia
- adipokines and hypertension
- adipokines and thrombosis/atherosclerosis
- adipokines and vascular/endothelial function, structure, and integrity
- adipokines and cardiovascular inflammation
- adipokines, adiposity, and cardiovascular disease in obesity
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