Biomarkers in Precision Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 1058
Special Issue Editor
Interests: biomarkers; therapeutic targets and compounds for Parkinson's disease and other neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases are progressive disorders characterized by the gradual loss of functional neurons in central and peripheral nervous systems, often leading to the demise of affected subjects. These conditions, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), typically manifest as cognitive decline, motor dysfunction, or both, severely impacting patients' quality of life. The underlying mechanisms are complex and multifactorial, involving protein misfolding, the accumulation of toxic aggregates, oxidative stress, mitochondrial dysfunction, and neuroinflammation. The lack of effective early diagnostic tools and disease-modifying treatments underscores the urgency of identifying reliable biomarkers to enhance our understanding, monitoring, and treatment of these devastating conditions. Biomarkers such as α-synuclein (α-syn) seeds, amyloid-beta (Aβ), tau proteins, and neurofilament light chain (NfL) have demonstrated potential in identifying early disease stages, tracking disease progression, and predicting outcomes in conditions like AD and PD. Advanced techniques, including neuroimaging, cerebrospinal fluid analysis, and blood-based assays, are being developed to enhance biomarker accuracy and accessibility. These innovations not only enable early and precise diagnosis but also facilitate personalized treatment strategies by identifying specific pathological pathways. The integration of biomarker discovery with artificial intelligence and multi-omics approaches holds promise for revolutionizing the management of neurodegenerative disorders.
The aim of this Special Issue is to discuss new promising biomarkers and novel techniques and approaches for biomarker identification and validation, which can support clinical practice regarding human neurodegenerative disorders.
Dr. Zhidong Zhou
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomarkers
- precision medicine
- novel techniques
- artificial intelligence
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
