Obesity: From Cellular Mechanism to Potential Molecular Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 25 February 2026 | Viewed by 13
Special Issue Editor
Special Issue Information
Dear Colleagues,
Obesity has become a global health challenge with profound metabolic, cardiovascular, and endocrine implications. The underlying molecular mechanisms of obesity are complex and involve genetic, epigenetic, and environmental factors that regulate key pathways, including those related to adipocyte differentiation, lipid metabolism, insulin signaling, and inflammatory responses. This Special Issue aims to delve into the cellular and molecular basis of obesity, emphasizing the role of specific genes, proteins, and metabolic pathways in the development and progression of this condition. We invite research that explores novel molecular biomarkers, signaling pathways, and cellular interactions that contribute to obesity, as well as innovative therapeutic strategies targeting these molecular mechanisms. Studies investigating the impact of obesity on other comorbidities, such as diabetes, cardiovascular diseases, and cancer, are also welcome. Additionally, we encourage submissions on emerging approaches for molecular interventions, including gene editing, small molecules, and biologics, aimed at reversing or preventing obesity-related dysfunction. We hope to provide a comprehensive understanding of the molecular underpinnings of obesity and offer new perspectives for therapeutic interventions in this ever-evolving field.
We warmly invite original research and review articles that contribute to advancing molecular insights into obesity and its potential therapies.
Dr. Veronica Jimenez
Guest Editor
Manuscript Submission Information
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Keywords
- metabolic pathways
- gene expression
- epigenetics
- obesity-related comorbidities
- molecular biomarkers
- adipogenesis
- therapeutic interventions
- small molecules
- gene therapy/gene editing
- obesity and cancer
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