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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Electrochemistry and Emerging Contaminants: Molecular Insights for Innovative Solutions
edited by
submission deadline 30 Aug 2025 | Viewed by 81 | Submission Open
Keywords: electrochemistry; chemical reactions; removal; environmental pollution
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Nutrition from Cereal Foods: Molecular Insights into Nutrition, Metabolism and Health Regulation
edited by Genyi Zhang
submission deadline 30 Aug 2025 | Viewed by 79 | Submission Open
Keywords: molecular breeding; cereal crops; bioactive compounds; metabolic syndrome; inflammation; gut health
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Advances in Adsorbing Materials
edited by Mounia Achak
submission deadline 30 Aug 2025 | Viewed by 76 | Submission Open
Keywords: adsorption process; adsorbing materials; bio-based adsorbents; regeneration and reusability; pollutant removal; wastewater treatment; industrial and environmental applications
(This special issue belongs to the Section Materials Science)
Molecular Pathways and Mechanisms of Lung Injury: From Environmental Agents to Clinical Implications
edited by and Cristina Porta
submission deadline 30 Aug 2025 | Viewed by 73 | Submission Open
Keywords: lung injury; lung cancer; pulmonary fibrosis; chronic obstructive pulmonary disease; acute respiratory distress syndrome; environmental pollutants and toxins; molecular and cellular mechanisms; biomarkers; therapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Modulating the Niche: Targeting the Tumor Microenvironment for Enhanced Therapy
edited by
submission deadline 30 Aug 2025 | Viewed by 72 | Submission Open
Keywords: microenvironment dynamics; immune modulation; biomarker discovery; tumor microenvironment; extracellular matrix; cancer therapy
(This special issue belongs to the Section Molecular Oncology)
The Role of Natural Compound for Reversing Cancer Therapy Resistance
edited by
submission deadline 30 Aug 2025 | Viewed by 72 | Submission Open
Keywords: cancer; natural compound; cell death; radioresistance; chemoresistance
(This special issue belongs to the Section Molecular Pharmacology)
Activation of the Blood–Brain Barrier and Neurological Dysfunction: 2nd Edition
edited by
submission deadline 30 Aug 2025 | Viewed by 70 | Submission Open
Keywords: blood– brain barrier; neuro-infectious diseases; microbes; traumatic brain injury; Alzheimer’ s disease; Parkinson’ s disease; schizophrenia; cerebral vasculature; vascular heterogeneity; white matter; gray matter; therapeutic delivery; opening the BBB; neuro vascular unit
(This special issue belongs to the Section Molecular Neurobiology)
Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets
edited by Uchenna John Unachukwu
submission deadline 30 Aug 2025 | Viewed by 65 | Submission Open
Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics
(This special issue belongs to the Section Molecular Biology)
Chemical Elicitors and Microbial Metabolites: Synergistic Mechanisms in Plant Systemic Resistance Induction
edited by Heewan Kang
submission deadline 30 Aug 2025 | Viewed by 56 | Submission Open
Keywords: chemical elicitors; Bacillus spp.; microbial metabolites; amino acids; defense induction; resistance mechanisms
(This special issue belongs to the Section Molecular Plant Sciences)
Advancements in the Electrochemical Detection of Biomolecules: From Sensing to Environmental Applications
edited by
submission deadline 30 Aug 2025 | Viewed by 50 | Submission Open
Keywords: biomolecules; nanomaterials; biorecognition; biomolecular detection; electrochemical
(This special issue belongs to the Section Molecular Biophysics)
Teleost in Biomedical Research submission deadline 31 Aug 2025 | 2 articles | Viewed by 6917 | Submission Open
Keywords: fish; teleost; experimental model; translational research; biomedicine; comparative studies
(This special issue belongs to the Section Molecular Biology)
Molecular and Cellular Mechanisms of Spinal Cord Injury and Repair
edited by Victoria Moreno-Manzano
submission deadline 31 Aug 2025 | 6 articles | Viewed by 5987 | Submission Open
Keywords: spinal cord injury; molecular changes; neuronal degeneration; circuit regeneration; transcriptomics; cell imaging; single-cell analysis; cell communication; behavior; functional outputs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Effect of Diet on Human Neurocognitive Function
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 5158 | Submission Open
Keywords: cognition; cognitive impairment; dietary pattern; nutrients; nervous cells
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Therapeutic Targets and Approaches to Manage Inflammation: Disappointing Past, Current Efforts and Faint Hopes
edited by Natasha Irrera
submission deadline 31 Aug 2025 | 3 articles | Viewed by 4381 | Submission Open
Keywords: inflammation; inflammatory pathways; resolution of inflammation; inflammasome; molecular pathways; anti-inflammatory response
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Bowel Disease: From Genetics to Treatment
edited by Dalin Li
submission deadline 31 Aug 2025 | 3 articles | Viewed by 4381 | Submission Open
Keywords: genetic predisposition; inflammatory bowel disease; genome-wide association study Crohn's disease; ulcerative colitis; bowel disease
(This special issue belongs to the Section Molecular Genetics and Genomics)
Mast Cell Disorders: From Molecular Mechanisms to Therapeutic Approaches
edited by Ehud Razin and
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2816 | Submission Open
Keywords: mastocytosis; mast cell activation syndrome; mast cell disorders; theurapeutic approaches; molecular mechanisms; tumor neovascularization; inflammatory diseases; asthma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bio-Nano Interactions—3rd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2512 | Submission Open
Keywords: nanoparticles; proteins; smart nanomaterial surfaces; selective protein binding; nanomaterials; abiotic material; biological systems; bio-inspired inorganic materials and DNA nanotechnologies
(This special issue belongs to the Section Molecular Nanoscience)
Chitosan Materials: Recent Advances in Modification, Properties and Application
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2451 | Submission Open
Keywords: chitosan materials; biomedical applications; agriculture and food industry; water treatment and environmental applications; nanotechnology and advanced materials
(This special issue belongs to the Section Macromolecules)
Molecular Mechanisms of Alzheimer’s Disease
edited by Sudip Dhakal
submission deadline 31 Aug 2025 | 5 articles | Viewed by 1970 | Submission Open
Keywords: Alzheimer’ s disease; amyloid beta; tauopathy; autophagy; stress response; mitochondrial dysfunction; cognitive decline; biomarkers; disease models
(This special issue belongs to the Section Molecular Neurobiology)
Cellular and Molecular Study of Neurodevelopmental and Neurological Disorders
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1708 | Submission Open
Keywords: autism spectrum disorder; ADHD; schizophrenia; intellectual disability; Alzheimer’ s disease; Parkinson’ s disorder; traumatic brain injury; epilepsy; neurodevelopmental disorders; neurological diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Identification of Novel Biomarkers Towards Improved Diagnosis and Management of Peripheral Vascular Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 1706 | Submission Open
Keywords: vascular pathophysiology; peripheral atherosclerosis; aneurysm; venous disorders; congenital vascular malformations; molecular biomarkers; diagnostic biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Viruses as Therapeutic Tools: Medical and Biotechnological Applications
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1528 | Submission Open
Keywords: molecular virology; virus– host interactions; immunology; gene therapy vectors; vaccines; antivirals
(This special issue belongs to the Section Molecular Microbiology)
Molecular Aspects of Reproductive Medicine
edited by Wei Chen
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1290 | Submission Open
Keywords: spermatogenesis; oogenesis; microenvironment; organ interactions; molecular regulation; gametogenesis; signaling pathways; reproductive disorders
(This special issue belongs to the Section Molecular Biology)
Antioxidants: The Molecular Guardians Against Oxidative Stress submission deadline 31 Aug 2025 | 2 articles | Viewed by 1273 | Submission Open
Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites
(This special issue belongs to the Section Biochemistry)
Insights into Novel Food Packaging Materials: Properties, Molecular Mechanisms, and Advanced Applications
edited by and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1241 | Submission Open
Keywords: food packaging; food materials; nano materials; degradable materials; edible materials; coating; shelf life; food preservation; postharvest control
(This special issue belongs to the Section Materials Science)
Role of MicroRNAs in Human Diseases: 2nd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1023 | Submission Open
Keywords: microRNAs; miRNAs; miRs; preclinical models; target interaction; regulatory networks; oncology; cancer biology; cardiovascular disease; neurodegenerative conditions; diagnostic applications; therapeutic development and clinical trials
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanisms of Neutrophil Extracellular Traps (Nets) in Human Diseases
edited by Eisuke F. Sato
submission deadline 31 Aug 2025 | 1 articles | Viewed by 948 | Submission Open
Keywords: neutrophil extracellular traps (NETs); neutrophils; inflammation; autoimmune diseases; cardiovascular diseases; tumor metastasis; thrombosis; molecular mechanisms; disease progression; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research in Asthma and Allergy
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 943 | Submission Open
Keywords: asthma; allergy; molecular mechanisms; exposome; treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Heart Failure: From Bench to Bedside
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 936 | Submission Open
Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Polymeric Biomaterials
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 849 | Submission Open
Keywords: biopolymers; biocomposites; nanomaterials; applications
(This special issue belongs to the Section Materials Science)
Bioactive Natural Compounds in Neuroscience and Neurodegenerative Disease Therapeutics
edited by
submission deadline 31 Aug 2025 | Viewed by 826 | Submission Open
Keywords: natural products; bioactive metabolites; secondary metabolites; neuronal development; neurotrophins; neuromedicine; neurodegeneration; memory disorders
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Microbial Genomics in the Omics Era
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 768 | Submission Open
Keywords: microbe; bioinformatics; DNA; RNA; protein; sequencing; structure; omics
(This special issue belongs to the Section Molecular Microbiology)
Therapeutic Horizons of Oligosaccharides: Molecular Mechanisms and Therapeutic Potential submission deadline 31 Aug 2025 | 1 articles | Viewed by 689 | Submission Open
Keywords: oligosaccharides; bacterial infection; multidrug-resistant
(This special issue belongs to the Section Molecular Microbiology)
Physiological and Pathological Hypoxia: The Battle between the Protective and Deleterious Effects of Oxygen Deprivation
edited by , , and Giacomo Strapazzon
submission deadline 31 Aug 2025 | 1 articles | Viewed by 669 | Submission Open
Keywords: physiological hypoxia; pathological hypoxia; hypoxia; signalling pathway; inflammation; oxygen transport
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 649 | Submission Open
Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders
(This special issue belongs to the Section Molecular Biology)
Biological and Molecular Aspects of Exercise Adaptation
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 623 | Submission Open
Keywords: exercise; redox homeostasis; metabolic state; biological; physiological
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition
edited by and Hongtuo Fu
submission deadline 31 Aug 2025 | 1 articles | Viewed by 583 | Submission Open
Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture
(This special issue belongs to the Section Molecular Biology)
Advances in Structural and Functional Properties of G-Quadruplexes and Aptamers submission deadline 31 Aug 2025 | 1 articles | Viewed by 582 | Submission Open
Keywords: G-quadruplex structure; aptamer; DNAzyme; catalytic G-quadruplexes
(This special issue belongs to the Section Molecular Biology)
Vitamin K in Disease Mechanisms and Therapy
edited by Maria Kokozidou
submission deadline 31 Aug 2025 | Viewed by 549 | Submission Open
Keywords: vitamins K; vitamins K-soluble proteins; vitamin K-dependent clotting factors; matrix Gla protein; calcification of blood vessels; vascular stiffness; cardiac output; stroke volume
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Environmental Influences on Cellular Responses
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 545 | Submission Open
Keywords: cell/environment interaction; cell signaling; mechanobiology; photobiology; thermobiology; enviromics; cell-cell communication; cell-cell interaction
(This special issue belongs to the Section Molecular Biology)
New Advances in Metabolic Engineering and Synthetic Biology of Yeasts
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 478 | Submission Open
Keywords: yeast metabolic engineering; synthetic biology; CRISPR-Cas9; metabolic pathways; bio-based chemicals; bioprocess engineering; yeast strain optimization; industrial biotechnology
(This special issue belongs to the Section Molecular Microbiology)
Glycoconjugates: From Structure to Therapeutic Application
edited by Rosana Ribić
submission deadline 31 Aug 2025 | 1 articles | Viewed by 469 | Submission Open
Keywords: glycoconjugates (glycoproteins and glycopeptides; glycolipids; proteoglycans); glyconanoparticles; carbohydrate-based therapeutics; glycomics; glycosylation; glycoengineering; glycobiology; synthesis of glycoconjugates; vaccine development; drug delivery; biomarkers; diagnostics; immunotherapy; regenerative medicine; therapeutic applications
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Diagnosis and Treatment of Colorectal Cancer
edited by Steven T. Brower and Robert Pergolizzi
submission deadline 31 Aug 2025 | Viewed by 459 | Submission Open
Keywords: colorectal cancer; biomarkers; epigenetics; targeted therapy; chemoresistance; personalized cancer therapy
(This special issue belongs to the Section Molecular Oncology)
New Insights into the Molecular Pathogenesis of Myeloproliferative Neoplasms submission deadline 31 Aug 2025 | 2 articles | Viewed by 457 | Submission Open
Keywords: myeloproliferative neoplasms; molecular diagnostic; targeted therapy; biomarkers; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cutting Edge Advances in Antitumor Properties of Natural Products submission deadline 31 Aug 2025 | Viewed by 433 | Submission Open
Keywords: natural product; cancer; cell signaling; cell death and differentiation; oxidative stress
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Amyotrophic Lateral Sclerosis: From Molecular Basis to Therapies
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 422 | Submission Open
Keywords: ALS; pathomechanisms; genetics; epigenetics; disease models; neuroinflammation; mithocondria; oxidative stress
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products from Plants: Association with Human Health and Therapeutic Benefits submission deadline 31 Aug 2025 | 1 articles | Viewed by 416 | Submission Open
Keywords: botanical products; phytochemicals; bio/pharmacological compounds; cellular and molecular targets; molecular and physiological mechanism; human health; disease prevention and treatment; inflammatory diseases; age-related disorders; chronic and (auto)immune diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advanced Research on Cancer Stem Cells
edited by
submission deadline 31 Aug 2025 | Viewed by 412 | Submission Open
Keywords: cancer stem cells; tumour microenvironment; pancreatic cancer; glioblastoma; gastric cancer; breast cancer; lung cancer; colorectal cancer; renal cancer; liver cancer; melanoma; leukemia; lymphoma
(This special issue belongs to the Section Molecular Oncology)
Advances in Photobiomodulation Therapy
edited by Maria Fernanda Setúbal Destro Rodrigues
submission deadline 31 Aug 2025 | 1 articles | Viewed by 368 | Submission Open
Keywords: photobiomodulation; dosimetric parameters; human diseases; modulation of inflammation; photobiomodulation therapy; molecular mechanisms; preclinical and clinical studies; therapeutic applications of PBM
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Focus on the Tryptophan Pathway
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 364 | Submission Open
Keywords: aging; indole-3-propionic acid; kynurenic acid; melatonin; serotonin; tryptophan
(This special issue belongs to the Section Molecular Biology)
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