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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cellular and Molecular Mechanisms of Acute Lung Injury

edited by

Ahilanandan Dushianthan

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3685 | Submission Open

Keywords: acute lung injury; lung infection; acute respiratory distress syndrom; neutrophil-mediated immune response; alveolar epithelial injury; pulmonary oedema

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cyclodextrin-Based Polymer Systems for Biomedical Applications

edited by

Antonella Piozzi

and

Iolanda Francolini

submission deadline 20 Aug 2025 | 1 articles | Viewed by 3617 | Submission Open

Keywords: cyclodextrins; polymers; grafting; drug delivery; hydrophobic drugs; wound healing; tissue engineering; antimicrobial systems; supramolecular systems

(This special issue belongs to the Section Macromolecules)

Functional Genomics in Translational Medicine

edited by

Cornelia Braicu

, Oana Zanoaga and

Ștefan Strilciuc

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3538 | Submission Open

Keywords: functional genomics; omics approaches; drug response/resistance; therapeutic targets; genomics and transcriptomic alteration; bioinformatic analysis; data integration; human disease; personalized medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Natural Products in Obesity: Novel Strategies and Molecular Mechanisms: 2nd Edition

edited by

Eugene Chang

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3537 | Submission Open

Keywords: obesity; inflammation; white adipose tissue; adipogenesis; oxidative stress; metabolic disease; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanism of Acute Myeloid Leukemia

edited by

Walter Fiedler

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3504 | Submission Open

Keywords: leukemia; cytokine; signal transduction; apoptosis; immune therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into the Immunopathology of Autoimmune and Drug Induced Liver Injury

edited by Eleni Geladari

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3499 | Submission Open

Keywords: liver disease; liver injury; immune system; immune dysregulation

(This special issue belongs to the Section Molecular Immunology)

Lipid Metabolism in Human Health and Diseases

edited by

Arianna Vignini

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3456 | Submission Open

Keywords: lipids; fatty acids; lipid metabolism; metabolic disorders; cardiovascular diseases; neurodegenerative diseases; cancers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Pharmacology of Medicinal Plants

edited by

Bruno Eto

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3441 | Submission Open

Keywords: medicinal plants; drug development; molecular pharmacology; clinical phytopharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Anxiolytic or Antidepressant Activity from Active Principles in Medicinal Plants

edited by Carolina López-Rubalcava and Erika Estrada Camarena

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3426 | Submission Open

Keywords: phytopharmacology; anxiety; depression; medicinal plants; animal models

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulation and Application of Bioactive Metabolites in Plants

edited by

Aoxue Luo

and

Yijun Fan

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3423 | Submission Open

Keywords: medicinal plants; biosynthesis; biological activity; regulation; pharmacological mechanism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Chronic Pain: Diagnosis, Pathophysiological Mechanisms and Treatment

edited by

Anna Maria Aloisi

and Thomas Herdegen

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3340 | Submission Open

Keywords: chronic pain; sex differences; age differences; pain therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Antibody–Drug Conjugates

edited by Bing Sun

submission deadline 20 Aug 2025 | 1 articles | Viewed by 3311 | Submission Open

Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry

(This special issue belongs to the Section Molecular Immunology)

Current Research on Plants as Natural Antioxidants

edited by

Viviana Maresca

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3293 | Submission Open

Keywords: plant-derived antioxidant; natural products; polyphenols; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Skin Inflammation

edited by

Nabiha Yusuf

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3258 | Submission Open

Keywords: skin inflammation; molecular diagnosis; dermatitis; molecular pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancing Climate Resilience in Horticultural Crops Through Omics Technologies

edited by

Yonghua Qin

and

Guibing Hu

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3245 | Submission Open

Keywords: horticultural crops; climate change; omics technologies; stress responses; abiotic stresses; food security; agricultural sustainability; genomics; transcriptomic; proteomics

(This special issue belongs to the Section Molecular Plant Sciences)

Inflammatory Bowel Disease: Focus on Molecular Research

edited by David Meriwether and

Hon Wai Koon

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3211 | Submission Open

Keywords: inflammatory bowel disease; gut microbiota; genomic sequencing; proteomic; lipidomic; metabolomic; therapy; biomarker; animal and organoid model

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis, Characterization and Application of Metal and Metal Oxide Nanomaterials

edited by

Paolo Prosposito

and

Luca Burratti

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3187 | Submission Open

Keywords: metal nanoparticles; metal nanoclusters; properties of metal nanostructures; optical sensing and bio-sensing; pollutant sensing; metal oxide-based materials; photocatalysis; decomposition of pollutants by photocatalysis; energy production; conversion; and storage; water treatment

(This special issue belongs to the Section Molecular Nanoscience)

Cellular and Molecular Mechanisms in Oxidative Stress-Related Diseases, 4th Edition

edited by

Alessia Remigante

and

Rossana Morabito

submission deadline 20 Aug 2025 | 3 articles | Viewed by 3182 | Submission Open

Keywords: molecular targets of oxidative stress in oxidative stress related-diseases; oxidative stress and oxidative stress-related pathologies; cellular response to oxidative stress; oxidative stress and apoptosis in oxidative stress-related diseases; oxidative stress and related cell signaling; cell adaptation to oxidative stress; biomarkers of oxidative stress in disease; beneficial effects of natural or synthetic antioxidants in oxidative stress-related diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Epigenetic Mechanisms in Growth and Neurodevelopmental Disorders

edited by

Mara Giordano

submission deadline 20 Aug 2025 | 1 articles | Viewed by 3120 | Submission Open

Keywords: growth defects; intellectual disability; epilepsy; autism spectrum disorders; epigenetic variations; copy number variations; next generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition

edited by

Massimiliano Gasparrini

and

Luca Mazzoni

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3102 | Submission Open

Keywords: IBD; dietary bioactive compounds; molecular mechanisms; health promotion; prevention; antioxidant; anti-inflammatory; nutritional support

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Computational Biology: Molecular Dynamics Simulation of Biomolecules

edited by

Paulino Gómez-Puertas

submission deadline 20 Aug 2025 | 1 articles | Viewed by 3033 | Submission Open

Keywords: computational biology; molecular dynamics; molecular simulation of rare diseases; computational design of antimicrobials; computational design of antivirals; molecular simulation of cancer-related processes; computational design of anti-cancer molecules; molecular simulation of biotechnology processes

(This special issue belongs to the Section Molecular Informatics)

New Perspectives in Steroidomics

edited by

Martin Hill

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3015 | Submission Open

Keywords: steroidomics; steroids; pathophysiology; physiology; diagnostics; treatment; prediction; prognosis; LC-MS/MS; GC-MS/MS

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Research on Transcriptional Regulation in Reproductive Biology

edited by

Anna Nynca

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2906 | Submission Open

Keywords: reproductive biology; molecular research; transcriptional regulations; signaling pathways; gene expression; cell biology

(This special issue belongs to the Section Molecular Biology)

Fish Nutrition Program and Epigenetic Regulation

edited by Linghong Miao

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2898 | Submission Open

Keywords: nutrients; nutritional strategies; molecule regulation; growth; immunity; reproduction; stress response; epigenetic modifications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advancements in Understanding Protein Misfolding Disorders and Cancer

edited by

Marijn Speeckaert

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2883 | Submission Open

Keywords: protein misfolding; cancer; amyloidosis

(This special issue belongs to the Section Molecular Oncology)

New Molecular Perspectives in Crustacean Neuroendocrinology

edited by

Tomer Ventura

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2848 | Submission Open

Keywords: neuroendocrinology; neuropeptides; functional genomics; arthropods development and reproduction; crustacean aquaculture

(This special issue belongs to the Section Molecular Biology)

New Mechanisms and Therapeutics in Neurological Diseases—4th Edition

edited by

Barbara Mroczko

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2804 | Submission Open

Keywords: neurodegeneration; neuroinflammation; neurodegenerative diseases; neurodevelopmental disorders; tumor markers; specific proteins

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Understanding of Allergen Exposome

edited by

Fernando Pineda

and

Ruperto Gonzalez-Perez

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2791 | Submission Open

Keywords: allergen exposome; profile allergen exposures; climatic change; airborne allergens; molecular triggers; microbial allergens

(This special issue belongs to the Section Molecular Immunology)

Bioactive Compounds, Smart Polymers and Functionalised Materials for Drug Delivery

edited by Emilia Szymańska

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2790 | Submission Open

Keywords: drug delivery system; bioactive compound; drug carrier; pharmacological activity; polymer

(This special issue belongs to the Section Materials Science)

Oral Squamous Cell Carcinoma: Insights into Molecular Pathways and Emerging Therapeutic Approaches

edited by

Silvia Pomella

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2735 | Submission Open

Keywords: oral squamous cell carcinoma; epigenetics; molecular genetics; gene expression targeted therapy; molecular biomarkers

(This special issue belongs to the Section Molecular Oncology)

Retinal Diseases: From Molecular Pathology to Therapies—2nd Edition

edited by

Peter Koulen

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2651 | Submission Open

Keywords: diabetic retinopathy; age-related macular degeneration; neuroprotection; retina; diabetic macular edema; therapy development; pathophysiology; retinitis pigmentosa; aging; eye trauma; vitreous; macula; choroideremia; stargardt disease; cone– rod dystrophy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Autoimmune Diseases

edited by

Tsvetelina Velikova

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2637 | Submission Open

Keywords: autoimmunity; autoimmune mechanisms; molecular pathogenesis; immune signalling pathways; cytokine regulation; epigenetics in autoimmunity; molecular biomarkers; gene expression profiling; regulatory T cells; immunogenetics; molecular therapeutics; signal transduction; immunometabolism; microRNA in autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Advances in Pro-Inflammatory and Anti-Inflammatory Cytokines

edited by

Juliann G. Kiang

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2606 | Submission Open

Keywords: pro-inflammation cytokine; anti-inflammation cytokine; chemotherapy; radiotherapy; signal transduction; microbiome– host response; sepsis; bone marrow; GI; brain

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Combinatorial Therapies for Spinal Cord Injury

edited by

Lingxiao Deng

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2545 | Submission Open

Keywords: molecular; cellular; engineering; spinal cord injury

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenic Microorganisms, Viruses and Therapeutic Strategies

edited by

Edward D’Antonio

and

Jair L. Siqueira-Neto

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2472 | Submission Open

Keywords: medicinal chemistry; pathogenic microorganisms; bacteria; fungi; viruses; pathogen; therapeutic

(This special issue belongs to the Section Molecular Microbiology)

Advancements in Perovskite and Tandem Solar Cell Technologies

edited by

Muhammad Adnan

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2460 | Submission Open

Keywords: perovskite solar cells; tandem photovoltaics; charge transporting materials; interfacial engineering; optoelectronic properties

(This special issue belongs to the Section Materials Science)

MicroRNAs and Other Non-Coding RNAs as Regulators, Biomarkers, and Therapeutic Targets, 2nd Edition

edited by

Wan Lee

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2392 | Submission Open

Keywords: non-coding RNAs; microRNA; lncRNA; circRNA; piRNA; biomarker; therapeutic target

(This special issue belongs to the Section Molecular Biology)

Health-Promoting Effects of Medicinal and Edible Plants and Their Molecular Mechanism

edited by

Baojun Xu

and

Matteo Bordiga

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2386 | Submission Open

Keywords: medicinal plants; edible plants; health-promoting effect; molecular mechanism; phytochemicals; diseases; curing targets; signaling pathway

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biological Research of Rhythms in the Nervous System

edited by Bernát Kocsis and Andreas Draguhn

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2378 | Submission Open

Keywords: mechanisms of rhythmic synchronization; rhythmic firing; neural network oscillations; rhythmic components in EEG; oscillopathy; theta and gamma rhythm; sleep spindle; rhythmic activity and cognition; pathology of rhythmic synchronization in the nervous system; altered rhythmic activity in neuropsychiatric disorders

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Research on CAR-T Cell Therapy

edited by

Yasushi Akahori

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2306 | Submission Open

Keywords: CAR T cell therapy; T cell activation; memory lymphocyte differentiation; cancer vaccine; antigen spread

(This special issue belongs to the Section Molecular Immunology)

Rheumatoid Arthritis: From Molecular Basis to Therapies

edited by

Gabriella Sármay

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2281 | Submission Open

Keywords: rheumatoid arthritis; autoimmune; intracellular signaling pathways; targeted therapy; inflammation; immunometabolic reprogramming; CD40; CD40 ligand; GM-CSF; PD-1; inhibitors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Endothelial Dysfunction and Its Related Cardiometabolic Disorders: From Mechanisms to Targeted Therapies

edited by

Nacci Carmela

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2266 | Submission Open

Keywords: endothelial dysfunction; endothelial activation; endothelial nitric oxide synthase; cardiometabolic disease; vascular inflammation; chemokines; adipocytokines; atherosclerosis; diabetes; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Crustacean Aquaculture

edited by Tom Levy and

Tomer Ventura

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2256 | Submission Open

Keywords: androgenic gland; aquaculture; crustaceans; disease management; gene silencing; genetic modification; monosex; selective breeding; sex reversal; yield improvement

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnostics and Treatment Advances in Lung Diseases

edited by Eirini Vasarmidi

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2247 | Submission Open

Keywords: lung diseases; pulmonary; alveolar; diagnosis; treatment; biomarkers; molecular; bronchoalveolar lavage; genetics; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Materials for Bioengineering and Biotechnology 2.0

edited by

Alexander Tsouknidas

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2232 | Submission Open

Keywords: biomaterials; nanomaterials; nanocarriers; extracellular vesicles; intercellular communication; tissue engineering; scaffolds

(This special issue belongs to the Section Materials Science)

New Advances in Neuroscience: Molecular Biological Insights

edited by

Palsamy Periyasamy

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2171 | Submission Open

Keywords: neurodegenerative diseases; neurodevelopmental disorders; neurohiv; drug abuse; neuropharmacology; epigenetics; exosomes; inflammasomes; biomarkers; gene therapy; stem cell therapy; deep brain stimulation; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; autism spectrum disorder; ADHD; dyslexia; neuroinflammation

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Biomedical Application of Polymeric Micelles

edited by

Ana Figueiras

Ivana Jarak

and

Francisco José De Baptista Veiga

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2167 | Submission Open

Keywords: polymeric micelles; nanomedicine; drug delivery; amphiphilic compounds; therapeutic applications

(This special issue belongs to the Section Macromolecules)

Design, Synthesis and Applications of the Task-Specific Molecules

edited by

Ye Yuan

and

Yang Yang

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2159 | Submission Open

Keywords: task-specific molecules; molecular design and synthesis; physical/chemical absorption; catalysis (including electrocatalysis; photocatalysis; etc.); mechanism on the molecular level; molecular dynamic simulations; optical materials; optoelectronic devices; photoelectric detection; semiconductors

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Pathogenesis of Preeclampsia: From a Molecular Perspective

edited by Jezid Miranda

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2092 | Submission Open

Keywords: preeclampsia; immune system; molecular mechanisms in preeclampsia; angiogenic factors; gene regulation; epigenetics; transcription factors in preeclampsia; translational research in preeclampsia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Non-Coding RNA in Physiology and Pathophysiology: Second Edition

edited by Maria Rosaria Tumolo

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2064 | Submission Open

Keywords: microRNA; long non-coding RNA; circular RNA; epigenetics; musculoskeletal pain; cardiovascular disease; metabolic disease; nervous system disorders; cancer; aging

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 651-700 on page 14 of 69.

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