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Recent Advances in Crustacean Aquaculture

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 987

Special Issue Editors


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Guest Editor
1. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA
2. Hopkins Marine Station, Stanford University, Pacific Grove, CA, USA
Interests: androgenic gland; aquaculture; crustaceans; disease management; gene silencing; genetic modification; monosex; selective breeding; sex-reversal; yield improvement

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Guest Editor
Centre for Bioinnovation, School of Science, Engineering and Technology, University of the Sunshine Coast, Sippy Downs, QLD 4556, Australia
Interests: androgenic gland; aquaculture; crustaceans; disease management; gene silencing; genetic modification; monosex; selective breeding; sex reversal; yield improvement
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Special Issue Information

Dear Colleagues,

The global demand for seafood has been steadily increasing for decades. However, meeting this demand is becoming exceedingly challenging due to overfishing and the adverse effects of climate change on aquatic ecosystems. This situation underscores the need for innovations that make aquaculture more sustainable, ensuring food security for the growing global population while preserving natural aquatic resources.

Crustaceans, including prawns, shrimps, crabs, lobsters, and crayfish, represent a highly valued and diverse segment of the seafood market. Rich in essential nutrients, crustacean meat plays a crucial role in human diets worldwide. Consequently, the rising demand for crustaceans in the global seafood market is driving significant research and development in aquaculture, with a particular focus on advancing biotechnologies to enhance sustainability, including the development of monosex populations, yield improvement, disease management, selective breeding, and other cutting-edge practices.

Innovations in this field include endocrine manipulations that influence growth and reproduction, androgenic gland manipulation for sex reversal to establish monosex cultures, CRISPR/Cas9 genetic modifications, next-generation sequencing techniques, and more.

This Special Issue welcomes studies contributing to recent advances and innovations in any aspect of crustacean aquaculture.

Dr. Tom Levy
Dr. Tomer Ventura
Guest Editors

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Keywords

  • androgenic gland
  • aquaculture
  • crustaceans
  • disease management
  • gene silencing
  • genetic modification
  • monosex
  • selective breeding
  • sex reversal
  • yield improvement

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Published Papers (1 paper)

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Research

16 pages, 4918 KiB  
Article
Chitin Synthase Is Required for Cuticle Formation and Molting in the Chinese Mitten Crab Eriocheir sinensis
by Ting Zhang, Yuning Hu, Siyu Lu, Yanfei Deng, Huimin Zhang, Yanhua Zhao, Yawen Yu, Hongbin Huang, Jun Zhou and Xuguang Li
Int. J. Mol. Sci. 2025, 26(5), 2358; https://doi.org/10.3390/ijms26052358 - 6 Mar 2025
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Abstract
Chitin synthase is an essential enzyme of the chitin synthesis pathway during molting. In this study, we identified and characterized a chitin synthase (EsCHS) gene in the Chinese mitten crab, Eriocheir sinensis. The spatio-temporal expression and functional role of EsCHS [...] Read more.
Chitin synthase is an essential enzyme of the chitin synthesis pathway during molting. In this study, we identified and characterized a chitin synthase (EsCHS) gene in the Chinese mitten crab, Eriocheir sinensis. The spatio-temporal expression and functional role of EsCHS were investigated. The open reading frame of EsCHS was 4725 bp long and encoded 1574 amino acid residues that contained the typical domain structure of the glycosyltransferase family 2. Phylogenetic analysis revealed that EsCHS belongs to the group I chitin synthase family. The expression of EsCHS was found in regenerative limbs, the cuticle and the intestines. During the molting cycle, EsCHS began to increase in the pre-molt stage and reached a significant peak in the post-molt stage. The knockdown of EsCHS resulted in the significant downregulation of chitin biosynthesis pathway genes, including TRE, HK, G6PI, PAGM and UAP. Moreover, the long-term RNAi of EsCHS resulted in thinning procuticles, abnormal molting and high mortality, suggesting that EsCHS is indispensable for the formation of chitin in the cuticle during molting. In conclusion, EsCHS is involved in the chitin biosynthesis pathway and plays an important role in molting in E. sinensis. These findings highlight the potential of incorporating EsCHS into selective breeding programs to optimize molting regulation and improve growth performance in crustacean aquaculture. Full article
(This article belongs to the Special Issue Recent Advances in Crustacean Aquaculture)
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