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Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 115

Special Issue Editors

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Guest Editor
Department of Agricultural, Food and Environmental Sciences, Università Politecnica delle Marche, Ancona, Italy
Interests: inflammation; oxidative stress; berries and antioxidant
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Agricultural, Food and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche 10, 60131 Ancona, Italy
Interests: fruits; breeding; diversity; traditional uses; ethnoveterinary; characterization of phytochemicals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Inflammatory bowel disease (IBD) represents chronic debilitating inflammatory disorders that can affect different parts of the gastrointestinal tract and are commonly correlated to two main diseases: Crohn’s disease and ulcerative colitis. These inflammatory conditions can lead to the development of severe complications such as anemia, malnutrition, infection, and an increased risk of colon cancer, one of the most common cancers worldwide. Despite intense research efforts, the etiology of IBD is not well established, but it is reasonably hypothesized that the interactions of multiple factors, including environmental and genetic factors, intestinal microbiota, and immune response, are involved in IBD promotion. Considering that there is no cure for IBD and that the incidence of this disorder has shown an increasing trend over the last few decades, nutritional support plays an important role in alleviating IBD symptoms and promoting healing. For all these reasons, it is very important to emphasize the scientific rationale behind the benefits of incorporating phytochemicals and other dietary bioactive compounds mainly present in fruits and vegetables as a nutritional supplement for the prevention and treatment of IBD, considering their consolidated and widely investigated anti-inflammatory and anti-oxidative effects.

Thus, this Special Issue will investigate the recent advances in the study of the role exerted by dietary bioactive compounds against IBD, focusing attention on the cellular processes, the molecular mechanisms, and the involved pathways, in order to elucidate their possible beneficial health effects and to promote their efficacy in this disease management. Topics related to both original and reviewed articles are welcome. Papers only containing extraction data will not be accepted because the focus should be on the chemical composition of ingredients and, more specifically, on describing their mechanism of action in improving human nutrition.

Dr. Massimiliano Gasparrini
Dr. Luca Mazzoni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • IBD
  • dietary bioactive compounds
  • molecular mechanisms
  • health promotion
  • prevention
  • antioxidant
  • anti-inflammatory
  • nutritional support

Published Papers

This special issue is now open for submission.
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