Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 2479
Special Issue Editors
Interests: inflammation; oxidative stress; berries and antioxidant
Special Issues, Collections and Topics in MDPI journals
Interests: fruits; breeding; diversity; traditional uses; ethnoveterinary; characterization of phytochemicals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammatory bowel disease (IBD) represents chronic debilitating inflammatory disorders that can affect different parts of the gastrointestinal tract and are commonly correlated to two main diseases: Crohn’s disease and ulcerative colitis. These inflammatory conditions can lead to the development of severe complications such as anemia, malnutrition, infection, and an increased risk of colon cancer, one of the most common cancers worldwide. Despite intense research efforts, the etiology of IBD is not well established, but it is reasonably hypothesized that the interactions of multiple factors, including environmental and genetic factors, intestinal microbiota, and immune response, are involved in IBD promotion. Considering that there is no cure for IBD and that the incidence of this disorder has shown an increasing trend over the last few decades, nutritional support plays an important role in alleviating IBD symptoms and promoting healing. For all these reasons, it is very important to emphasize the scientific rationale behind the benefits of incorporating phytochemicals and other dietary bioactive compounds mainly present in fruits and vegetables as a nutritional supplement for the prevention and treatment of IBD, considering their consolidated and widely investigated anti-inflammatory and anti-oxidative effects.
Thus, this Special Issue will investigate the recent advances in the study of the role exerted by dietary bioactive compounds against IBD, focusing attention on the cellular processes, the molecular mechanisms, and the involved pathways, in order to elucidate their possible beneficial health effects and to promote their efficacy in this disease management. Topics related to both original and reviewed articles are welcome. Papers only containing extraction data will not be accepted because the focus should be on the chemical composition of ingredients and, more specifically, on describing their mechanism of action in improving human nutrition.
Dr. Massimiliano Gasparrini
Dr. Luca Mazzoni
Guest Editors
Manuscript Submission Information
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Keywords
- IBD
- dietary bioactive compounds
- molecular mechanisms
- health promotion
- prevention
- antioxidant
- anti-inflammatory
- nutritional support
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