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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Aug 2025 | 1 articles | Viewed by 592 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Lung Diseases and Lung Transplantations: Molecular Pathogenesis and Advanced Therapies

edited by Christopher Lambers

submission deadline 20 Aug 2025 | Viewed by 590 | Submission Open

Keywords: lung disease; lung transplantation; ECMO; EVLP; LAS; antibody-mediated rejection (AMR); CLAD; RAS/BOS; immunosuppression; pathogenesis; cell-free DNA; IPF therapies; gene therapies; stem cell therapies; immunotherapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights and Design Strategies for Carbonaceous Nanomaterials

edited by

Magdalena Krystyjan

and

Gohar Khachatryan

submission deadline 20 Aug 2025 | Viewed by 589 | Submission Open

Keywords: carbon nanomaterials; carbon (nano)fillers; graphene; carbon nanotubes; carbon quantum dots; nanoparticles; nanostructures

(This special issue belongs to the Section Molecular Nanoscience)

New Insights into the Pathobiology of T Cell Malignancies

edited by

Grzegorz Przybylski

submission deadline 20 Aug 2025 | Viewed by 570 | Submission Open

Keywords: T cell malignancies

(This special issue belongs to the Section Molecular Oncology)

Revolutionizing Antifungal Therapeutics: From Understanding to Intervention

edited by

Célia Fortuna Rodrigues

submission deadline 20 Aug 2025 | Viewed by 557 | Submission Open

Keywords: fungi; antifungal; biofilm; Candida; Aspergillus; Trichoderma

(This special issue belongs to the Section Molecular Microbiology)

Mechanistic and Small Molecule Discoveries for Therapeutic Advances in Hypertrophic and Dilated Cardiomyopathies

edited by Osha Roopnarine

submission deadline 20 Aug 2025 | Viewed by 539 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathies; cardiomyopathies

(This special issue belongs to the Section Molecular Pharmacology)

Drug Development Breakthroughs: From Novel Antimicrobials to Targeted Cancer Drugs

edited by

Christos Papaneophytou

submission deadline 20 Aug 2025 | Viewed by 534 | Submission Open

Keywords: drug development; molecular science; small-molecule inhibitors; biopharmaceuticals; peptides; cancer therapy

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in the Application of NMR Spectroscopy to Study Structure and Dynamics of Proteins

edited by Harindranath Kadavath

submission deadline 20 Aug 2025 | Viewed by 525 | Submission Open

Keywords: proteins; dynamics; NMR spectroscopy; structure– dynamics– function; protein folding; protein– protein interactions; in-cell NMR; biomolecular structure; intrinsically disordered proteins (IDPs)

(This special issue belongs to the Section Molecular Biology)

Physiological and Molecular Mechanisms of Abiotic Stresses in Crops

edited by

Yousef Alhaj Hamoud

submission deadline 20 Aug 2025 | Viewed by 525 | Submission Open

Keywords: abiotic stress; plant physiology; signaling pathways; plant molecular biology; resistance; crop yield and quality

(This special issue belongs to the Section Molecular Plant Sciences)

Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 20 Aug 2025 | 1 articles | Viewed by 501 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies of Hematologic Malignancies

edited by

Myunggon Ko

submission deadline 20 Aug 2025 | 1 articles | Viewed by 501 | Submission Open

Keywords: hematologic malignancies; molecular mechanisms; genetic and epigenetic aberrations; molecular diagnosis; targeted therapy and biomarkers

(This special issue belongs to the Section Molecular Oncology)

Mechanisms of Protein–Ligand Interactions in Therapies for Lifestyle Diseases and Their Complications

edited by Agnieszka Szkudlarek

submission deadline 20 Aug 2025 | Viewed by 478 | Submission Open

Keywords: chronic diseases and their complications; protein– ligand interactions; protein modifications; therapeutic efficacy; binding affinity; serum proteins; pharmaceutical applications; biomedical research

(This special issue belongs to the Section Molecular Biology)

The Role of Genome in Cancer Therapy

edited by Yoav Smith and Hovav Nechushtan

submission deadline 20 Aug 2025 | Viewed by 473 | Submission Open

Keywords: genome analysis; molecular therapy; drug resistance; cancer genetic

(This special issue belongs to the Section Molecular Genetics and Genomics)

Yeast Models in Genetic and Molecular Research

edited by

Ee Sin Chen

submission deadline 20 Aug 2025 | Viewed by 444 | Submission Open

Keywords: yeast; genome; epigenetics; chemogenomics; DNA repair

(This special issue belongs to the Section Molecular Biology)

Solanaceae Biology: From Genetics to Metabolism

edited by

Pengxiang Fan

submission deadline 20 Aug 2025 | Viewed by 438 | Submission Open

Keywords: Solanaceae; nightshade family; tomato; potato; tobacco; eggplant; genetics; metabolism; crop improvement; specialized metabolite

(This special issue belongs to the Section Molecular Plant Sciences)

Cancer Immunotherapy Biomarkers

edited by Ilias P. Nikas,

Ioannis Pateras

and

Apostolos Zaravinos

submission deadline 20 Aug 2025 | Viewed by 429 | Submission Open

Keywords: tumor microenvironment; tumor immunology; cancer biomarkers; immunotherapy; immunohistochemistry; pathology; personalized medicine; omics technologies; prognosis and therapy; bioinformatics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Tumorigenesis of Human and Animal Stem Cells

edited by

Daniela Salvatori

submission deadline 20 Aug 2025 | 1 articles | Viewed by 422 | Submission Open

Keywords: malignancy; stem cells; safety; chromosal aberrations; animal; human; teratoma assay; in vitro assays

(This special issue belongs to the Section Molecular Oncology)

Cellular Senescence as a Therapeutic Target in Cancer: Mechanisms, Challenges, and Therapeutic Opportunities

edited by

Mi Kyung Park

submission deadline 20 Aug 2025 | Viewed by 414 | Submission Open

Keywords: cellular senescence; cancer therapy; therapeutic targeting; senolytic drugs; senescence-associated secretory phenotype (SASP)

(This special issue belongs to the Section Molecular Oncology)

Cellular Senescence and the Senescence-Associated Secretory Phenotype (SASP) in Age-Related Diseases

edited by Jordi Olloquequi

submission deadline 20 Aug 2025 | Viewed by 408 | Submission Open

Keywords: cellular senescence; senescence-associated secretory phenotype (SASP); age-related diseases; atherosclerosis; chronic obstructive pulmonary disease (COPD); type 2 diabetes mellitus (T2DM); non-alcoholic fatty liver disease (NAFLD); Alzheimer’ s disease (AD); inflammation; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Experimental Models and Applications in Muscle Regeneration

edited by

Daiva Bironaite

submission deadline 20 Aug 2025 | Viewed by 407 | Submission Open

Keywords: stem cells; internal and external stimuli; scaffolds; signaling systems; muscle regeneration mechanisms

(This special issue belongs to the Section Molecular Biology)

Exploring the Impact of the Biological Clock on Health and Disease

edited by

Bojlul Bahar

submission deadline 20 Aug 2025 | Viewed by 396 | Submission Open

Keywords: circadian rhythm; inflammation; oxidative stress; energy balance; metabolic syndrome; ageing; cancer; diabetes; obesity; entrainment; synchrony; melatonin

(This special issue belongs to the Section Molecular Biology)

Roles of Phytochemicals in Cancer Prevention and Therapeutics: 2nd Edition

edited by

Daniel Gabriel Pons

submission deadline 20 Aug 2025 | Viewed by 392 | Submission Open

Keywords: phytochemicals; cancer prevention; cancer therapeutics; oxidative stress; inflammation; energetic metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology

edited by Richard H. W. Funk

submission deadline 20 Aug 2025 | Viewed by 387 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

Insights into Neurological and Psychiatric Diseases from Invertebrate Models

edited by

Efthimios M. C. Skoulakis

submission deadline 20 Aug 2025 | Viewed by 379 | Submission Open

Keywords: disease model development; disease model validation; GWAS validation; ameliorative approaches; pharmacogenetics; pharmacoproteomics; disease mechanisms; suppressor/enhancer genetic screens; synthetic lethality screens; biomarker screens and validation

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Heparin, Heparan Sulfate and Heparanase, 2nd Edition

edited by

Nobuaki Higashi

submission deadline 20 Aug 2025 | Viewed by 368 | Submission Open

Keywords: allergy; angiogenesis; cancer metastasis; cellular trafficking; exosome; fibrosis; glycocalyx; glycosaminoglycans; heparan sulfate; heparanase; heparin; immune responses; inflammation; inbibitor development; sepsis/SIRS (systemic inflammatory response syndrome); sulfatase; viral infections

(This special issue belongs to the Section Macromolecules)

The Role of Cannabinoids in Human Health and Disorder

edited by

Grazia Chiellini

and Beatrice Polini

submission deadline 20 Aug 2025 | Viewed by 366 | Submission Open

Keywords: cannabinoids; cannabinoid receptors; endocannabinoid system; ECS synthetic modulators; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Biological Determination of Physical Injury

edited by

Sorin Hostiuc

submission deadline 20 Aug 2025 | Viewed by 365 | Submission Open

Keywords: molecular markers; physical injury; micro-RNA; dating of traumatic injuries

(This special issue belongs to the Section Molecular Biology)

Exploring the Role of Antioxidants in Supplements and Drug Responses

edited by

Maria Greabu

submission deadline 20 Aug 2025 | Viewed by 363 | Submission Open

Keywords: NSAIDs; glucocorticoids; vitamin E; antioxidants; oxidative stress; inflammation

(This special issue belongs to the Section Molecular Immunology)

Advancements and Applications of Phyto-Nanotherapy in Targeted Disease Treatment

edited by

Adewale Fadaka

and

Nicole Remaliah Samantha Sibuyi

submission deadline 20 Aug 2025 | Viewed by 358 | Submission Open

Keywords: phyto-nanotherapy; medicinal plants; nanoparticles; targeted drug delivery; phytochemicals; phytotherapy; green nanotechnology; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Mitochondria in Neurodegenerative Disorders: Unveiling Mechanisms and Therapeutic Strategies

edited by

Saeid Ghavami

and Mohamad-Reza Aghanoori

submission deadline 20 Aug 2025 | Viewed by 356 | Submission Open

Keywords: neurodegenerative disorders; energy homeostasis and metabolism; mitochondrial dysfunction; mitochondrial dynamics; mitophagy and autophagy; synaptic function; axonal transport; oxidative stress; calcium homeostasis; treatments targeting mitochondria; mitochondrial biogenesis; neuroprotection; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Roles and Functions of Micronutrients in Gut Microbiota and Intestinal Inflammation

edited by

Chao Wang

submission deadline 20 Aug 2025 | Viewed by 351 | Submission Open

Keywords: micronutrients; gut microbiota; intestinal inflammation; intestinal barrier; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Melatonin in Plants: 3rd Edition

edited by

Małgorzata M. Posmyk

submission deadline 20 Aug 2025 | Viewed by 323 | Submission Open

Keywords: melatonin; phytomelatonin; plants; seed germination; seasonal and circadian rhythms; flowering; fruit ripening; plant immunity; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Fruit Crops Development

edited by

Xingguo Li

submission deadline 20 Aug 2025 | Viewed by 319 | Submission Open

Keywords: fruit crops; fruit tree; proteomics; genomics; metabolomics; biotic stress; abiotic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Nanotechnology in Drug Delivery: Applications and Perspectives

edited by Ádám Juhász

submission deadline 20 Aug 2025 | Viewed by 315 | Submission Open

Keywords: nanostructured materials; drug delivery; drug– carrier interactions; hydrogel; aerogels; associated colloids; surfactants; macromolecules; blood– brain barrier; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Artificial Intelligence in Human Disease: Current and Future Perspectives in Digital Medicine

edited by

Dumache Raluca-Oana

submission deadline 20 Aug 2025 | Viewed by 307 | Submission Open

Keywords: molecular genetics; artificial intelligence; pharmacogenomics; internet of things; molecular pathology; genomic medicine

(This special issue belongs to the Section Molecular Informatics)

Inflammation and Metabolic Response in Mitochondrial Diseases

edited by

Guido Primiano

submission deadline 20 Aug 2025 | Viewed by 306 | Submission Open

Keywords: mitochondrial diseases; mitochondria; mtDNA; metabolic remodeling; inflammation; immunity; cell death; neurodegenration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic Mechanisms of Neurological Disorders

edited by

Patrícia Maciel

and Sara Duarte-Silva

submission deadline 20 Aug 2025 | Viewed by 305 | Submission Open

Keywords: neurodevelopmental disorders; neurodegenerative disorders; neuropsychiatric disorders; genetics; molecular biology; cellular models; animal models; pathogenesis; biomarkers; therapeutic targets; drug discovery; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Insights in Nanomaterials and Electroactive Molecules—in Memory of Prof. Royce W. Murray

edited by

Zeev Porat

submission deadline 20 Aug 2025 | Viewed by 291 | Submission Open

Keywords: nanomaterials; organic electrochemistry; macromolecules and polymers; analytical chemistry

(This special issue belongs to the Section Molecular Nanoscience)

Tumor Specific Immunotherapeutic Targets

edited by

Roberto Perris

submission deadline 20 Aug 2025 | Viewed by 282 | Submission Open

Keywords: immunotherapy; immunotherapeutics; tumour-specific antigens; immunotherapeutic targets; multi-omics approaches

(This special issue belongs to the Section Molecular Immunology)

Signaling Pathways in Neuroinflammation or Neurodegenerative Disorders

edited by

Marika Cordaro

submission deadline 20 Aug 2025 | Viewed by 279 | Submission Open

Keywords: inflammation; neuroinflammation; oxidative stress; neurodegenerative disorders; pathology; molecular pathways; dysregulation; mitochondrial dysfunction

(This special issue belongs to the Section Molecular Neurobiology)

New Insights into Hyaluronan in Human Medicine

edited by

Monica Salamone

submission deadline 20 Aug 2025 | Viewed by 265 | Submission Open

Keywords: hyaluronan; regenerative medicine; inflammation; cancer therapy; metabolomics ; hyaluronidases; cell– matrix interaction; glucose metabolism; pathological processes

(This special issue belongs to the Section Biochemistry)

Advances in the Purinergic System

edited by Margarete Dulce Bagatini

submission deadline 20 Aug 2025 | Viewed by 245 | Submission Open

Keywords: purinergic system; receptors; ectonucleotidases; CD39; CD73; purinergic signaling

(This special issue belongs to the Section Biochemistry)

Research Progress of Nanodrug Delivery System

edited by Kenta Morita

submission deadline 20 Aug 2025 | Viewed by 236 | Submission Open

Keywords: drug delivery; nanomaterials; nanomedicine; pharmacokinetics; theranostics; imaging; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Obesity and Cancer Risk: Molecular Mechanisms and Perspectives

edited by

Hendrik Lehnert

submission deadline 20 Aug 2025 | Viewed by 235 | Submission Open

Keywords: epidemiology of obesity and cancer; experimental models of cancer in obesity; genetic and epigenetics of obesity and metabolic dysfunction associated cancer; tumor microenvironment; basis of metastatic spread of cancer in obesity; therapeutic modeling and targeting

(This special issue belongs to the Section Molecular Oncology)

Nrf1/2/3 and Other Antioxidant Transcription Factors in Health and Disease

edited by

Eleonora Stanca

submission deadline 20 Aug 2025 | Viewed by 126 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Aug 2025 | Viewed by 100 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Development and Applications of Biodegradable and Bioactive Materials

edited by

Mercedes Ana Peltzer

submission deadline 20 Aug 2025 | Viewed by 66 | Submission Open

Keywords: biopolymers; bioplastics; sustainability; food packaging; medicine and cosmetic; bioactive compounds; wound healing; active and intelligent packaging

(This special issue belongs to the Section Materials Science)

Molecular Studies of Endometriosis and Associated Diseases

edited by Sarah J Holdsworth-Carson

submission deadline 21 Aug 2025 | 4 articles | Viewed by 6028 | Submission Open

Keywords: adenomyosis; autoimmune diseases; cardiometabolic conditions; endometriosis; fatigue; heavy menstrual bleeding; irritable bowel syndrome; migraine; painful bladder syndrome; pelvic floor muscle dysfunction; pelvic inflammatory disease; pelvic pain; peritoneal adhesions; polycystic ovarian syndrome; pregnancy complications; ovarian cancer; uterine fibroids

(This special issue belongs to the Section Molecular Biology)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 22 Aug 2025 | 1 articles | Viewed by 1188 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Endothelial Cells in Cancer: Molecular Advance

edited by Dae Joong Kim

submission deadline 22 Aug 2025 | Viewed by 152 | Submission Open

Keywords: tumor angiogenesis; metastasis; VEGFs; FGFs; Ang2; immune surveillance; antigen presentation; EC adhesion molecules; LYVE-1; lymphatic vessel; antigen-presenting cell; lymphocytes; high endothelial venule

(This special issue belongs to the Section Biochemistry)

Displaying special issue 751-800 on page 16 of 69.

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