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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Biology in Forensic Science: Past, Present and Future, 2nd Edition submission deadline 20 Jun 2025 | 5 articles | Viewed by 13232 | Submission Open
Keywords: genetics and molecular biology; forensic molecular biology; forensic and biological sciences; forensic genetics; aging and genetics; molecular biology and pharmacology; molecular biology and toxicology; translational pharmacology; biochemistry
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Adipose Tissue and Gene Expression submission deadline 20 Jun 2025 | 8 articles | Viewed by 13203 | Submission Open
Keywords: adipose tissue dysfunction; lipomatosis; fat distribution; lipodystrophy; micro-RNA; dysmetabolism; diet; inflammation; rare disease; transcription
(This special issue belongs to the Section Molecular Biology)
Nitric Oxide Signalling in Plants
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 13081 | Submission Open
Keywords: nitric oxide; NO-mediated transcriptome; post-transcription modification; S-nitrosylation; N assimilation; NO homeostasis; gaseous NO; cellular signaling; nitric oxide signaling; transcription factors (TFs)  
(This special issue belongs to the Section Molecular Plant Sciences)
Muscle Atrophy: From Bench to Bedside 2.0
edited by
submission deadline 20 Jun 2025 | 3 articles | Viewed by 12913 | Submission Open
Keywords: muscle atrophy; human diseases; proteolysis; protein synthesis; proteolytic systems system; therapeutic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Angiotensin in Human Health and Diseases
edited by
submission deadline 20 Jun 2025 | 4 articles | Viewed by 12372 | Submission Open
Keywords: renin– angiotensin– aldosterone system; angiotensin subtype receptors; cardiovascular disease; kidney diseases; stroke; metabolic abnormalities; obesity and adipose tissue; oxidative stress and inflammation; blood pressure and salt sensitivity
(This special issue belongs to the Section Molecular Biology)
Application of Biotechnology to Dental Treatment submission deadline 20 Jun 2025 | 6 articles | Viewed by 12025 | Submission Open
Keywords: biotechnology; implant material; titanium; zirconia; PEEK; in vitro; in vivo
(This special issue belongs to the Section Materials Science)
New Insights into Cardiac Ion Channel Regulation 3.0 submission deadline 20 Jun 2025 | 5 articles | Viewed by 11878 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Postharvest Biology and Molecular Research of Fruits
edited by
submission deadline 20 Jun 2025 | 6 articles | Viewed by 11829 | Submission Open
Keywords: postharvest biology; fruit; storage technologies; molecular mechanisms; senescence; chilling injury; browning; nutrition; disease; toxin
(This special issue belongs to the Section Molecular Plant Sciences)
Advanced Research on Regenerative Medicine submission deadline 20 Jun 2025 | 5 articles | Viewed by 11477 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Prostate Cancer
edited by
submission deadline 20 Jun 2025 | 7 articles | Viewed by 11263 | Submission Open
Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Genome Editing
edited by Lei Gao
submission deadline 20 Jun 2025 | 5 articles | Viewed by 11178 | Submission Open
Keywords: plant genome editing; Cas9/Cas12a; CRISPR/CRISPRa/CRISPRi; anti-CRISPR; gene editing; off target impact; prime editing; bioinformatics/database
(This special issue belongs to the Section Molecular Plant Sciences)
Forward in Vasculitis: Genetics and Beyond
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 10800 | Submission Open
Keywords: systemic vasculitides; ethiopathogenesis; risk factors; genetics; genomics; proteomics; transcriptomics; epigenetics; molecular pathways; novel therapeutic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insight into Novel Coatings: Design, Synthesis, and Applications submission deadline 20 Jun 2025 | 3 articles | Viewed by 10754 | Submission Open
Keywords: composite coatings; protective coatings; antibacterial coatings; superhydrophobic coatings; superhydrophilic coatings; anti-icing coatings; bioactive coatings; photocatalytic coatings  
(This special issue belongs to the Section Materials Science)
Molecular Insights into Hair Regeneration
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 10493 | Submission Open
Keywords: hair loss; androgenic alopecia; alopecia areata; cell therapy; antibody therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Neuroinflammation and Neurodegeneration: Molecular Mechanism and Novel Therapy
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 10407 | Submission Open
Keywords: neuroinflammation; neurodegeneration; neuroimmunology; toxic protein aggregates; autolysosomal dysfunction; metabolic defects; aberrant receptor signaling; neuron-glia interactions; glia-immune interactions; omics characterizations; therapeutic development; biomarker discovery
(This special issue belongs to the Section Molecular Neurobiology)
Physiology and Molecular Biology of Plant Stress Tolerance: 2nd Edition
edited by
submission deadline 20 Jun 2025 | 15 articles | Viewed by 10376 | Submission Open
Keywords: plant– pathogen interactions; biotic and abiotic stress; plant innate immunity; phytohormones; genes
(This special issue belongs to the Section Molecular Plant Sciences)
Natural Compounds: Advances in Antimicrobial Activity submission deadline 20 Jun 2025 | 6 articles | Viewed by 10325 | Submission Open
Keywords: natural compounds; multidrug-resistant microorganisms; biofilm; synergistic effect; nanotechnologies; delivery systems; machine learning; clinical infections
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Polymers, Polymer Blends, and Polymeric Drug Release Systems with Antiviral or Antibacterial Effect—2nd Edition
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 10313 | Submission Open
Keywords: antimicrobial polymers; antifungal polymers; antiviral polymers; polymers as drug delivery systems; application of biocide polymers; biocide polymers coatings and surfaces; advantages and disadvantages of biocide polymers; mode of action of biocide polymers
(This special issue belongs to the Section Macromolecules)
Molecular Research on Embryo Developmental Potential
edited by
submission deadline 20 Jun 2025 | 10 articles | Viewed by 10199 | Submission Open
Keywords: embryo developmental potential; oocyte quality; sperm quality; non-invasive techniques; molecular biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mental Disorders and Translational Psychiatry: From Neurobiology to Therapeutic Perspective
edited by Lionella Palego and
submission deadline 20 Jun 2025 | 4 articles | Viewed by 10156 | Submission Open
Keywords: mental disorders; illness heterogeneity; comorbidity; treatment resistance; neurobiology; applied neuroscience; translational psychiatry; peripheral biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research on Gynecological Cancers: Ovarian Cancer, Endometrial Cancer, and Gestational Trophoblastic Disease
edited by Laura Mariuzzi, and
submission deadline 20 Jun 2025 | 6 articles | Viewed by 10151 | Submission Open
Keywords: ovarian cancer; endometrial cancer; gestational trophoblastic disease; prognostic factors; oncogenes; molecular genetics and genomics; DNA genotyping; cancer stem cells; epigenomics; signaling pathways; extracellular vesicles; tumour heterogeneity; tumour microenvironment; immune checkpoint inhibitors; new targets; molecular target
(This special issue belongs to the Section Molecular Oncology)
The Microbiota and Its Association with Cellular Transformation and Metabolic Changes, 2nd Edition submission deadline 20 Jun 2025 | 2 articles | Viewed by 9661 | Submission Open
Keywords:  
(This special issue belongs to the Section Molecular Microbiology)
Schizophrenia: From Molecular Mechanism to Therapy submission deadline 20 Jun 2025 | 4 articles | Viewed by 9564 | Submission Open
Keywords: schizophrenia; neurodevelopmental disorders; therapeutic approaches; drug of abuse; mental disorders
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mechanisms in Biofilm Formation, Tolerance and Control: 2nd Edition
edited by and Lúcia Chaves Simões
submission deadline 20 Jun 2025 | 8 articles | Viewed by 9499 | Submission Open
Keywords: adhesion; antimicrobial action; antimicrobial resistance; biofilm development; biofilm matrix; biofilm structure; quorum sensing; motility; surfaces
(This special issue belongs to the Section Molecular Microbiology)
Molecular and Cellular Perspectives on Wound Healing submission deadline 20 Jun 2025 | 4 articles | Viewed by 9409 | Submission Open
Keywords: chronic wound healing; scarring; biomarkers; inflammation; angiogenesis; infection; extracellular matrix; biomaterials; tissue regeneration; therapeutic targets; innovative therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Food Derived Biomolecules in Reducing the Risk of Diseases
edited by
submission deadline 20 Jun 2025 | 2 articles | Viewed by 9244 | Submission Open
Keywords: food derived biomolecules; chronic diseases; antioxidant; anti-inflammatory
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights of Biomarkers in Neurodegenerative Diseases
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 8771 | Submission Open
Keywords:   amyloid-β ;   tau phosphorylated;   tau;   GFAP;   neurofilaments;   TDP-43;   progranulin;   a-synuclein;   magnetic resonance imaging;   positron emission tomography;   dopamine transporter scan
(This special issue belongs to the Section Molecular Neurobiology)
Editorial Board Members’ Collection Series: New Insights into Neuroproteins submission deadline 20 Jun 2025 | 6 articles | Viewed by 8755 | Submission Open
Keywords: neuroproteins; S100B; glial fibrillary acidic protein; neuron-specific enolase; alpha-synuclein; amyloid proteins
(This special issue belongs to the Section Molecular Neurobiology)
Editorial Board Members’ Collection Series: Stem Cells and Regenerative Medicine submission deadline 20 Jun 2025 | 4 articles | Viewed by 8740 | Submission Open
Keywords: stem cells; regenerative medicine; niche; tissue engineering; cell signaling; differentiation; stem cells therapies; cell culture technologies
(This special issue belongs to the Section Molecular Biology)
New Perspective in the Molecular Pathways Involved in Acute and Chronic Lung Injury
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 8653 | Submission Open
Keywords: acute lung injury; chronic lung injury; molecular pathways; treatment; therapeutic targets; inflammation; oxidative stress; respiratory disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Gut Microbiota and Intestinal Diseases submission deadline 20 Jun 2025 | 3 articles | Viewed by 8589 | Submission Open
Keywords: dysbiosis; homeostasis; intestinal disease; bioactive molecules; gut health
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Psychiatric Therapies submission deadline 20 Jun 2025 | 3 articles | Viewed by 8494 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
Biopolymers in Drug and Gene Delivery Systems 3.0
edited by
submission deadline 20 Jun 2025 | 4 articles | Viewed by 8400 | Submission Open
Keywords: biopolymers; drug delivery; gene delivery; biodegradable polymers; biocompatible polymers; nanomedicine
(This special issue belongs to the Section Macromolecules)
Anticancer Drug Discovery Based on Natural Products
edited by Su-Yun Lyu
submission deadline 20 Jun 2025 | 4 articles | Viewed by 8380 | Submission Open
Keywords: anticancer drug discovery; natural products; phytochemicals; traditional medicine; drug development; preclinical studies; clinical trials
(This special issue belongs to the Section Molecular Pharmacology)
Diabetes-Related Cognitive Impairment Diseases
edited by
submission deadline 20 Jun 2025 | 1 articles | Viewed by 8257 | Submission Open
Keywords: Alzheimer’ s disease; amyloid-hyperglycemia; insulin resistance; mitochondrial dysfunction; cerebrovascular diseases; metabolic diseases; neuroinflammation; tau hyperphosphorylation; type 2 diabetes; vascular cognitive impairment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Comprehensive Insights into Molecular Mechanisms and Pathophysiology of Spinal Cord Injury
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 8095 | Submission Open
Keywords: spinal cord injury; pathophysiology; molecular mechanisms; omics approaches; genomics; proteomics; metabolomics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Proteomics in Cancer
edited by
submission deadline 20 Jun 2025 | 5 articles | Viewed by 8074 | Submission Open
Keywords: cancer; proteomics; mass spectrometry; molecular targets; biomarker
(This special issue belongs to the Section Molecular Oncology)
Recent Progress in Regenerative Therapy Using Blood-Derived Biomaterials
edited by , and Tomoharu Mochizuki
submission deadline 20 Jun 2025 | 4 articles | Viewed by 7939 | Submission Open
Keywords: blood-derived biomaterial; platelet-rich plasma; autologous protein solution; mechanism; platelet; coagulation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research on HIV Virus and Infection
edited by
submission deadline 20 Jun 2025 | 4 articles | Viewed by 7892 | Submission Open
Keywords: HIV; viral proteins; immunogenetics; pathogenesis
(This special issue belongs to the Section Molecular Immunology)
Advances in the Application of Nanomaterials in Environmental Remediation
edited by
submission deadline 20 Jun 2025 | 3 articles | Viewed by 7852 | Submission Open
Keywords: porous materials; nanomaterials; adsorption mechanism; metal– organic framework materials; heavy metals; organic contaminants; pharmaceuticals; molecular simulation; morphology
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Research on the Pancreatic Cancer submission deadline 20 Jun 2025 | 3 articles | Viewed by 7839 | Submission Open
Keywords: PDAC; biomarker; metastasis; chemoresistance
(This special issue belongs to the Section Molecular Oncology)
Bioactive Lipids and Their Derivatives in Biomedical Applications submission deadline 20 Jun 2025 | 3 articles | Viewed by 7687 | Submission Open
Keywords: bioactive lipids; phospholipids; sphingolipids; signaling; prostanoids; fatty acids; endocannabinoids; cholesterol; cell membrane; receptors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Obstetrical and Gynaecological Disorders submission deadline 20 Jun 2025 | 6 articles | Viewed by 7612 | Submission Open
Keywords: female reproduction; infertility; embryo development; genealogical disorders; cancer; biomarkers; molecular therapy; epigenetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring the Molecular Mechanisms of the Microbiome in Reproductive Health and Reproductive Immunity submission deadline 20 Jun 2025 | 2 articles | Viewed by 7489 | Submission Open
Keywords: microbiome; infertility; reproduction; male; female; pregnancy; immunology; immune tolerance
(This special issue belongs to the Section Molecular Immunology)
Macrophages in Human Diseases and Their Treatment
edited by
submission deadline 20 Jun 2025 | 3 articles | Viewed by 7324 | Submission Open
Keywords: macrophages; organ dysfunction; human diseases; involvement of macrophages in treatment options
(This special issue belongs to the Section Molecular Immunology)
Molecular Research of Multi-omics in Cancer
edited by
submission deadline 20 Jun 2025 | 4 articles | Viewed by 7202 | Submission Open
Keywords: bioinformatics; biomedical informatics; high-throughput sequencing (HTS)/next-generation sequencing (NGS); DNA-Seq/genomics; RNA-Req/transcriptomics; mass spectrometry/proteomics  
(This special issue belongs to the Section Molecular Oncology)
Exploring Cytochromes P450: Drug Metabolism, Endogenous Metabolism, and Human Health
edited by Ewa Bromek, and Wojciech Kuban
submission deadline 20 Jun 2025 | 4 articles | Viewed by 7004 | Submission Open
Keywords: cytochrome P450; drug metabolism; endogenous substrate metabolism; liver metabolism; brain metabolism
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
COVID-19: Advances in Pathophysiology and Therapeutics submission deadline 20 Jun 2025 | 4 articles | Viewed by 6998 | Submission Open
Keywords: COVID-19; SARS-CoV-2; pathophysiology; immunology; pharmacotherapy; biomarkers; comorbidities; clinical management; disease severity; treatment efficacy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancements in Personalized Medicine: Integrating Genomic Insights and Therapeutic Strategies submission deadline 20 Jun 2025 | 3 articles | Viewed by 6914 | Submission Open
Keywords: personalized medicine; genomic insights; therapeutic strategies; molecular profiling; precision medicine; molecular targets; precision oncology; genomic biomarkers
(This special issue belongs to the Section Molecular Genetics and Genomics)
New Insights into Radiation Oncology
edited by
submission deadline 20 Jun 2025 | 3 articles | Viewed by 6710 | Submission Open
Keywords: particle irradiation; proton and carbon ion irradiation; molecular and cellular radiobiology; influence of particle irradiation on physiology and signal transduction cascades of tumor cells; radiation physics; radiation therapy of malignant bone tumors
(This special issue belongs to the Section Molecular Oncology)
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