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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Non-Coding RNAs as Key Regulators in Human Disease Processes

edited by

Beatrice Polini

submission deadline 20 Jul 2026 | 1 articles | Viewed by 945 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; therapeutic targets; molecular mechanisms; RNA-based therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Pesticide Toxicity and Action

edited by

Fatima Smagulova

submission deadline 20 Jul 2026 | 1 articles | Viewed by 910 | Submission Open

Keywords: neonicotinoids; sex-specific effects; brain– gut– microbiome; endocrine organs; genotoxic effects; epigenetic effects

(This special issue belongs to the Section Molecular Toxicology)

The Characterization and Application of Enzymes in Bioprocesses, 2nd Edition

edited by

Loredana Marcolongo

submission deadline 20 Jul 2026 | 1 articles | Viewed by 842 | Submission Open

Keywords: biocatalysts; enzymatic characterization; enzymatic action; protein engineering; biocatalysts application; bioprocessing

(This special issue belongs to the Section Biochemistry)

Omics Approach to Uncovering Signalling and Gene Regulation in Plants

edited by Xiang Li and Jingchun Shi

submission deadline 20 Jul 2026 | 1 articles | Viewed by 818 | Submission Open

Keywords: omics; plant signalling; gene regulation; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Molecular Research on Photocatalytic Applications

edited by Hassan Ait Ahsaine

submission deadline 20 Jul 2026 | 1 articles | Viewed by 771 | Submission Open

Keywords: photocatalysis; photocatalytic degradation; molecular catalysts; photocatalysts; functional materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Exploring Natural Products for Antimicrobial Innovation: New Paths and Promising Leads

edited by

Shagufta Perveen

submission deadline 20 Jul 2026 | Viewed by 710 | Submission Open

Keywords: antimicrobial agents; drug resistance; plant-derived compounds; bioactive molecules; phytochemicals; marine natural products; fungal metabolites; novel drug discovery; microbial pathogens; natural product isolation; drug development; biotechnology in antimicrobial research

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biological Pathways and Nutraceutical Compounds in Genetic Disease Treatment

edited by

Deborah J. Good

submission deadline 20 Jul 2026 | Viewed by 699 | Submission Open

Keywords: micronutrients; supplements; functional foods; inherited disease; microbiome; RNA expression; protein expression; signaling pathways; DNA methylation; animal models; cell lines; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Host-Pathogen Interactions in Plants: Molecular Mechanisms and Sustainable Strategies

edited by Muhammad Rahil Afzal and Misbah Naz

submission deadline 20 Jul 2026 | 1 articles | Viewed by 648 | Submission Open

Keywords: plant immunity; plant– pathogen interactions; molecular mechanisms; effector biology; hormonal crosstalk; non-coding RNAs and epigenetics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insight into Nematodes Management

edited by

Giada D'Errico

submission deadline 20 Jul 2026 | 1 articles | Viewed by 638 | Submission Open

Keywords: biological control; micro-organisms; molecular identification; biodiversity; climatic changes; soil nema-todes; cultural practices; host plant resistance; anaerobic soil disinfection; biofumigation

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Insights in Rapeseed Abiotic Stress

edited by

Ahsan Ayyaz

submission deadline 20 Jul 2026 | 1 articles | Viewed by 570 | Submission Open

Keywords: rapeseed (Brassica napus); abiotic stress; drought tolerance; salinity stress; heavy metal toxicity; molecular mechanisms; stress signaling; omics (transcriptomics; proteomics; metabolomics); molecular breeding; CRISPR-Cas9; stress-responsive genes; hormone cross-talk; epigenetic regulation; stress resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Autophagy, 2nd Edition

edited by

Maria Ines Vaccaro

submission deadline 20 Jul 2026 | Viewed by 547 | Submission Open

Keywords: ATG molecules; transcriptional and post translational modification; selective pathways; secretory pathways; complexes diseases; degenerative processes; inflammatory diseases; tumorigenesis; metabolism; proteostasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecular Research on High-Fat Diet on Human Health and Disease

edited by

Berta Alejandra Espinosa Escalona

submission deadline 20 Jul 2026 | 1 articles | Viewed by 542 | Submission Open

Keywords: obesity; diet-induced obesity; antioxidants

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Innovations in Organic Framework Materials: Expanding the Horizons of COFs, MOFs, and HOFs for Advanced Applications

edited by Bhausaheb Dhokale

submission deadline 20 Jul 2026 | Viewed by 536 | Submission Open

Keywords: COF; MOF; HOF; synthesis; molecular applications; porous materials; molecular engineering; membranes; theoretical studies; energy

(This special issue belongs to the Section Materials Science)

Neuronal Differentiation: From Pathology to Therapeutic Strategies

edited by

Marzia Lecchi

submission deadline 20 Jul 2026 | Viewed by 508 | Submission Open

Keywords: neuronal differentiation; molecular mechanisms of neurodifferentiation; neurodegenerative diseases; ischemic stroke; spinal cord and brain injury; neural tissue recovery; regeneration therapy; stem cells

(This special issue belongs to the Section Molecular Neurobiology)

Epigenetic and RNA-Based Regulation in Cancer: Mechanism, Therapeutic Targets, and Translational Perspectives

edited by

Moon Nyeo Park

submission deadline 20 Jul 2026 | Viewed by 470 | Submission Open

Keywords: molecular underpinnings of DNA; histone; RNA-based epigenetic regulation; small molecules and epigenetic inhibitors; epigenetic signatures; oncology

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into Environmental Toxicology in Cancer

edited by

Silvia Vivarelli

submission deadline 20 Jul 2026 | Viewed by 468 | Submission Open

Keywords: environmental carcinogenesis; toxic exposure; exposome; occupational cancer risk; biomarkers of exposure; new approach methodologies (NAMs)

(This special issue belongs to the Section Molecular Oncology)

Recent Research on Glycosylation

edited by

Yang Zhang

submission deadline 20 Jul 2026 | Viewed by 459 | Submission Open

Keywords: protein glycosylation; protein folding; cell signaling; immune regulation; glycoproteins

(This special issue belongs to the Section Biochemistry)

Neurohormones in Cardiac Fibrosis and Heart Failure

edited by

Helmy M. Siragy

submission deadline 20 Jul 2026 | Viewed by 447 | Submission Open

Keywords: heart failure; neurohormones; cardiac fibrosis; angiotensin II; aldosterone; endothelin; catecholamines

(This special issue belongs to the Section Molecular Biology)

Advanced Strategies for Melanoma Immunotherapy

edited by

Andrzej Mackiewicz

and

Piotr Rutkowski

submission deadline 20 Jul 2026 | Viewed by 429 | Submission Open

Keywords: melanoma immunotherapy; immune Checkpoint Inhibitors; combination therapies; biomarkers; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

The Role of Extracellular Vesicles in Drug Delivery

edited by

Sara Biagiotti

and

Michele Guescini

submission deadline 20 Jul 2026 | Viewed by 429 | Submission Open

Keywords: red blood cells; red blood cell-extracellular vesicles; drug delivery systems; RNA therapies; EV engineering

(This special issue belongs to the Section Molecular Biology)

Biomaterials for Bone Treatment, Replacement and Regeneration: Focus on Regeneration and Inflammation

edited by

Mike Barbeck

submission deadline 20 Jul 2026 | Viewed by 419 | Submission Open

Keywords: biomaterials ; bone substitute ; inflammation ; foreign body response ; bone regeneration

(This special issue belongs to the Section Materials Science)

The Role of Embryonic Stem Cells in Human Disease and Health

edited by Fahad Kidwai

submission deadline 20 Jul 2026 | Viewed by 405 | Submission Open

Keywords: emrbryonic stem cells; human disease and health; regenerative therapy

(This special issue belongs to the Section Molecular Biology)

Vitamin D and New Vitamin D Analogs

edited by

Yagamare Fall

submission deadline 20 Jul 2026 | Viewed by 397 | Submission Open

Keywords: vitamin D; vitamin D receptor; vitamin D analogs; synthesis; clinical applications; cancer; anti-proliferation; therapeutic target

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advancing Mental Disorder Therapies: Drug Repositioning and Translational Insights from Animal Models

edited by Claudia Bregonzio and Mariela Fernanda Pérez

submission deadline 20 Jul 2026 | Viewed by 389 | Submission Open

Keywords: anxiety; depression; Parkinson's disease; Alzheimer; schizophrenia; neurotransmitter imbalance; novel treatments; new pharmacological targets; preclinical studies

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Lipopolysaccharides

edited by

Satish Raina

and

Gracjana Klein

submission deadline 20 Jul 2026 | Viewed by 384 | Submission Open

Keywords: LPS structural diversity; lipid A; amino arabinose and phosphoethanolamine; TLR4; antibiotic resistance; Lpt transport system; phospholipids and fatty acids; cell envelope stress; lipid A acyltransferases

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Rhizospheric Microbial Interactions

edited by

Jelena Lozo

submission deadline 20 Jul 2026 | 1 articles | Viewed by 372 | Submission Open

Keywords: plant– microorganism interactions; rhizosphere community; secretory systems; secondary metabolites; volatile compounds

(This special issue belongs to the Section Molecular Microbiology)

Effects of Co-Exposure of Pollutants on Animal Models

edited by

Chiara Maria Motta

submission deadline 20 Jul 2026 | Viewed by 371 | Submission Open

Keywords: environmental health; biological systems; toxic exposure; co-exposure; physiological mechanisms; behavioral responses; gene expression; epigenetic effects; molecular research

(This special issue belongs to the Section Molecular Toxicology)

Bioactive Small Molecules in Tissue Repair and Regeneration

edited by

Ildiko Bock-Marquette

submission deadline 20 Jul 2026 | Viewed by 370 | Submission Open

Keywords: small molecules; organ and tissue regeneration; development; aging

(This special issue belongs to the Section Molecular Biology)

Nanomedicine for Diagnostic and Therapeutic Application

edited by

Nicola D'Avanzo

and Antonella Barone

submission deadline 20 Jul 2026 | Viewed by 368 | Submission Open

Keywords: polymeric nanoparticles; lipid nanoparticles; diagnostic; theranostic; targeted drug delivery; nonovesicles; prescion medicine

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights in Medical Microbiology and Infectious Diseases: The Role of Artificial Intelligence and Machine Learning

edited by

Alberto Rizzo

submission deadline 20 Jul 2026 | Viewed by 366 | Submission Open

Keywords: molecular diagnostics; pathogen genomics; antimicrobial resistance; host– pathogen interaction; infectious diseases surveillance; artificial intelligence; machine learning

(This special issue belongs to the Section Molecular Informatics)

Characterization of Immune and Inflammatory Tumor Microenvironment on Canine, Feline and Human Species

edited by

Luís Monteiro

submission deadline 20 Jul 2026 | Viewed by 360 | Submission Open

Keywords: inflammation; tumor microenvironment; cancer biomarkers; comparative pathology; cancer epidemiology; cancer risk factors; molecular diagnostics; proteomics; treatment response; targeted therapy; immunotherapy; translation cancer research

(This special issue belongs to the Section Molecular Oncology)

Roles of Exosomes in Health and Disease

edited by

Paulo Pereira

submission deadline 20 Jul 2026 | Viewed by 356 | Submission Open

Keywords: exosomes; extracellular vesicles; intercellular communication; diagnostics; therapeutics; disease; biomarkers; cellular biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Development and Applications of Biodegradable and Bioactive Materials

edited by

Mercedes Ana Peltzer

submission deadline 20 Jul 2026 | Viewed by 350 | Submission Open

Keywords: biopolymers; bioplastics; sustainability; food packaging; medicine and cosmetic; bioactive compounds; wound healing; active and intelligent packaging

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of Antiviral Agents and Antiviral Therapy

edited by

Jesus Alberto Silvas

submission deadline 20 Jul 2026 | Viewed by 327 | Submission Open

Keywords: therapeutics; high-throughput screening; viral reverse genetics; luciferase; fluorescent; compound; repurpose; antiviral; diagnostics

(This special issue belongs to the Section Molecular Immunology)

Fish and Amphibians: Exploring Genetic, Developmental, and Endocrine Mechanisms

edited by

Gad Degani

submission deadline 20 Jul 2026 | Viewed by 316 | Submission Open

Keywords: gene expression; fish physiology; amphibian development; endocrine regulation; comparative genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Role of DNA Methylation Signatures in Genetic Disorders

edited by

Jair Tenorio-Castano

submission deadline 20 Jul 2026 | Viewed by 305 | Submission Open

Keywords: DNA methylation; genetic disorders; episignature; genomic medicine; differentially methylated regions

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Molecular Mechanisms of Human Papillomavirus Family (HPV) Induced Oncogenesis, 2nd Edition

edited by

Subhasis B. Biswas

submission deadline 20 Jul 2026 | Viewed by 293 | Submission Open

Keywords: human papillomavirus (HPV); oncogenesis; mechanism; diagnosis; classification; etiology; pathophysiology; biochemistry; genetics; molecular biology; epidemiology; cervical cancer; oropharyngeal cancer; oncology

(This special issue belongs to the Section Molecular Oncology)

Natural Product-Inspired Anticancer Drug Development

edited by

Erzsébet Mernyák

submission deadline 20 Jul 2026 | Viewed by 291 | Submission Open

Keywords: anticancer; antiproliferative; cytotoxic; natural product; drug development; semi-synthesis; total synthesis; structure– activity relationship; computational simulation; enzyme inhibition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Natural Products with Antimicrobial Activities

edited by Jose Javier Sanz Gomez

submission deadline 20 Jul 2026 | Viewed by 277 | Submission Open

Keywords: bioactive compounds; biotechnological substances; essential oils; plant extracts; mechanism of action; interactions; biofilms; active packaging; technological processes; safety

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Phytochemicals in Cancer Therapy: From Preclinical Studies to Clinical Practice

edited by Mounir Tilaoui

submission deadline 20 Jul 2026 | Viewed by 258 | Submission Open

Keywords: phytochemicals; cancer therapy; molecular mechanisms; signaling pathways; programmed cell death; tumor microenvironment; drug resistance; preclinical models; clinical translation; adjuvant therapy

(This special issue belongs to the Section Molecular Oncology)

Regenerative Medicine for Tendon: Harnessing Stem Cell Potential

edited by

Maria Camilla Ciardulli

submission deadline 20 Jul 2026 | Viewed by 251 | Submission Open

Keywords: stem cells; endogenic differentiation; three-dimensional in vitro tendon models; immunomodulation; biomimetic scaffolds; in vivo tendon models; dynamic cultures

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Small Molecules and Antibodies for Targeted Cancer Therapies

edited by Chitra Subramanian

submission deadline 20 Jul 2026 | Viewed by 250 | Submission Open

Keywords: targeted therapy; small molecules; antibodies; drug resistance; metastasis; cancer treatment; mechanism of resistance

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Infectious Disease Detection: Novel Assays and Biomarkers

edited by

Leonardo M. Leony

submission deadline 20 Jul 2026 | Viewed by 202 | Submission Open

Keywords: in vitro diagnostics (IVD); imunoassays; nucleic acid testing; serology; point-of-care testing (PoCT)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Active Compounds Targeting Obesity

edited by Mariana Sarto Figueiredo

submission deadline 20 Jul 2026 | Viewed by 190 | Submission Open

Keywords: obesity; bioactive compounds; functional foods; food as medicine; natural products; comorbidities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Molecular Biology of Haematology

edited by Valéria Tavares

submission deadline 20 Jul 2026 | Viewed by 182 | Submission Open

Keywords: haematopoiesis; molecular biology; genomics; epigenomics; computational biology; hematologic neoplasms; biomarkers; liquid biopsy; precision medicine

(This special issue belongs to the Section Molecular Biology)

Advances in Maternal–Fetal/Neonatal Interactions: Implications for Infant Immunity and Long-Term Health

edited by

Monika Słupecka-Ziemilska

submission deadline 20 Jul 2026 | Viewed by 176 | Submission Open

Keywords: immune development; microbiome; epigenetic mechanisms; autoimmune diseases; breastfeednig

(This special issue belongs to the Section Molecular Immunology)

Evolving Landscape of Cardiovascular Pathophysiology

edited by

Pooja Shivshankar

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1339 | Submission Open

Keywords: biomarker discovery in cardiovascular pathophysiology; precision diagnostics-novel contrast agents combined with PET/CT; MRI; machine learning/AI and clinical implementations in cardiology; cardio-metabolic disease; inflammation and immunity in cardiovascular diseases; mechanisms of non-coding RNAs and microRNAs in cardiac diseases; translational research in large animals bridging the rodent re-search with human pathophysiology; targeted therapies- genetic therapies/gene editing approach (CRISPR); stem cell therapies; and therapeutic mRNA and siRNA-based approaches

(This special issue belongs to the Section Biochemistry)

Neurodegenerative Diseases: Molecular Mechanisms and Therapies, 4th Edition

edited by

Zhidong Zhou

and

Alexandre Hiroaki Kihara

submission deadline 25 Jul 2026 | 1 articles | Viewed by 909 | Submission Open

Keywords: neurodegeneration; neurodegenerative diseases; protein aggregation; pathogenesis; therapy; mitochondria; neuroinflammation; oxidative stress; cell therapy; clinical trial

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Systemic Sclerosis

edited by

Filomena Napolitano

and

Nunzia Montuori

submission deadline 25 Jul 2026 | 1 articles | Viewed by 903 | Submission Open

Keywords: systemic sclerosis; autoimmune disease; fibrosis; vasculopathy; immune dysregulation; fibroblasts; endothelial dysfunction; epigenetics; transcriptomics; biomarkers

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Chronic Lung Diseases

edited by

Ramcés Falfán-Valencia

submission deadline 25 Jul 2026 | Viewed by 487 | Submission Open

Keywords: interstitial lung diseases; chronic respiratory diseases; genetic susceptibility; genomic; cytokine networks; metalloproteinases; inflammasome; inflammatory cytokines; telomere length

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 701-750 on page 15 of 65.

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