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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Cervical Cancer and Its Therapy

edited by Ilaria Cuccu and

Violante Di Donato

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2980 | Submission Open

Keywords: cervical cancer; cervical cancer surgery; fertility-sparing techniques; targeted therapy; immunotherapy; immune checkpoint inhibitors; DNA damage repair inhibitors; antibody– drug conjugates; precision medicine; oncological outcomes

(This special issue belongs to the Section Molecular Oncology)

Crop Stress Biology and Molecular Breeding: 5th Edition

edited by

Youxiong Que

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2940 | Submission Open

Keywords: biotic and abiotic stress; variety improvement; crop stress biology; molecular breeding; biological basis; signal transduction pathway; agronomic traits; excellent germplasm

(This special issue belongs to the Section Molecular Plant Sciences)

Inflammation in Pregnancy and Childbirth

edited by

Małgorzata Szczuko

and Maciej Ziętek

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2938 | Submission Open

Keywords: pregnancy; labor; eicosanoid; chronic inflammation; cytokines; intestinal dysbiosis; mitogen-activated protein kinase; nuclear factor kappa-light-enhancer-activated B cell; maresins; resolvins and protectins

(This special issue belongs to the Section Molecular Immunology)

Current Developments in Glioblastoma Research and Therapy: 2nd Edition

edited by

Aleksandra Majchrzak-Celińska

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2859 | Submission Open

Keywords: diagnostic; prognostic and predictive biomarkers of glioblastoma; ways to target glioma stem cells; targeting glioblastoma-related signaling pathways; epigenetics of glioblastoma; treatment resistance mechanisms; novel treatment options for glioblastoma; combinatorial therapies; immunotherapy; nanotherapy; the application of CRISPR/Cas9 in glioma research; molecular testing of long-term glioblastoma survivors

(This special issue belongs to the Section Molecular Neurobiology)

Modulating the Niche: Targeting the Tumor Microenvironment for Enhanced Therapy

edited by

Dong Min Lee

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2817 | Submission Open

Keywords: microenvironment dynamics; immune modulation; biomarker discovery; tumor microenvironment; extracellular matrix; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Melanoma: Molecular Mechanism and New Agents for Prevention and Therapy

edited by

M. Letizia Motti

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2812 | Submission Open

Keywords: melanoma; therapy resistance; melanoma microenvironment (MME); melanoma plasticity; epigenetic mechanism; predictive markers; prognostic markers; extracellular vesicles; molecular therapy; natural molecules

(This special issue belongs to the Section Molecular Oncology)

Micro(nano) Plastics and Estrogens as Endocrine Disruptors Meet the Female Reproductive System, Breast and Colon: What Is Going On?

edited by

Anna Maria Giuseppina Poma

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2787 | Submission Open

Keywords: micro(nano) plastics; estrogens; endocrine disruptors; female reproductive system; breast; colon

(This special issue belongs to the Section Molecular Biology)

CRISPR/Cas Systems and Genome Editing—3rd Edition

edited by

Dmitry Karpov

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2767 | Submission Open

Keywords: CRISPR/Cas; bacterial argonauts; transcription regulation; genome editing; genome editing tools

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Molecular Network, Key Biomarkers, and Therapeutic Targets in Colorectal Cancer

edited by

Katharina M. Robertson

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2749 | Submission Open

Keywords: inflammation; metabolism; tumor-associated macrophages; tumor microenvironment; early-onset colorectal cancer; colorectal neoplasms; obesity; immunotherapy; epigenetics; cytokines; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Study of Functional Foods and Nutrients in Human Health Interventions

edited by

Rui Jiao

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2717 | Submission Open

Keywords: functional foods; molecular mechanisms; nutrient bioavailability; chronic disease prevention; health interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nucleic Acid Recognition and Pharmaceutical Ligand Design

edited by

Marijana Radić Stojković

and

Atanas Kurutos

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2680 | Submission Open

Keywords: nucleic acid recognition; ligand design; analytical techniques; computational chemistry; therapeutics

(This special issue belongs to the Section Macromolecules)

Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications

edited by

Daniel José Barbosa

and

Renata Silva

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2632 | Submission Open

Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies

(This special issue belongs to the Section Molecular Neurobiology)

Drugs—from Chemical Structure to Biological Activity

edited by

Sravani Sana

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2621 | Submission Open

Keywords: hit molecule; lead optimization; drug design; virtual screening; molecule descriptors; structure– activity relationship; pharmacokinetic/ADME profile; in vitro biological activity

(This special issue belongs to the Section Molecular Pharmacology)

Aging: From Molecular Mechanisms and Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Darío Acuña-Castroviejo

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2612 | Submission Open

Keywords: human aging; molecular clock; aging genes; epigenetics; nutrigenomics; inflammaging; stem cells; telomeres; mitochondria; brain-gut axis; brain-muscle axis; gut microbiota; chronodisruption

(This special issue belongs to the Section Molecular Biology)

Towards Complex Molecular Cancer Therapies

edited by

Luba Hunáková

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2578 | Submission Open

Keywords: precision medicine; immune system harnessing; targeted therapies TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Immune Response to Virus Infection and Vaccines

edited by

Giulia Matusali

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2558 | Submission Open

Keywords: immunogenicity; emerging pathogen vaccination; molecular and cellular determinants of vaccine responses in immunocompromised individuals; predictive markers of immune response; laboratory methods to dissect immune responses to infections and vaccinations

(This special issue belongs to the Section Molecular Immunology)

Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes

edited by

Eugenio Luigi Iorio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2479 | Submission Open

Keywords: redox systems; aging and disease; nutraceuticals; probiotics; animals; plants; aquatic ecosystems; microbiomes

(This special issue belongs to the Section Molecular Biology)

Editorial Board Member's Collection Series: The Memory of the Immune Cells

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2438 | Submission Open

Keywords: immunological memory; innate immune memory; dendritic cells; natural killer cells; macrophage memory

(This special issue belongs to the Section Molecular Immunology)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2400 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Viral Vector-Mediated Genome Editing Therapy

edited by

Izumu Saito

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2366 | Submission Open

Keywords: genome editing; adenovirus vector; knock-in; inherited disease; viral vectors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Intestinal 3D Culture, Organoids and Gut-on-Chip in Intestinal Disorders

edited by

Vanessa D’Antongiovanni

and

Carolina Pellegrini

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2326 | Submission Open

Keywords: 3D cultures; gut-on-chip; intestinal organoids; spheroids; organotypic cultures; morphological studies; pharmacological studies; intestinal cancer; inflammatory bowel disease; intestinal functional disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2320 | Submission Open

Keywords: bone; stem cells; immunomodulation; biomaterials; bone regeneration; bone repair; bone diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology of Lung Cancer: From Intrinsic to Acquired Resistance Mechanisms

edited by

Federico Pio Fabrizio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2277 | Submission Open

Keywords: lung cancer; NSCLC; cancer therapy; resistance; DNA methylation

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Adsorbing Materials

edited by Mounia Achak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2258 | Submission Open

Keywords: adsorption process; adsorbing materials; bio-based adsorbents; regeneration and reusability; pollutant removal; wastewater treatment; industrial and environmental applications

(This special issue belongs to the Section Materials Science)

Environmental Heavy Metals with Their Benefits and Risks for Human Health

edited by

Rolf Teschke

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2212 | Submission Open

Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis

(This special issue belongs to the Section Molecular Toxicology)

Pathophysiological Insights, Biomarkers and New Therapeutic Strategies in Immune-Mediated Disorders and Neurodegenerative Diseases

edited by

Eleonora Virgilio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2182 | Submission Open

Keywords: neurodegeneration; neuroimmunology; inflammation; biomarkers; treatment; pathophysiology; multiple sclerosis; myasthenia gravis; neurodegenerative disease

(This special issue belongs to the Section Molecular Immunology)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2158 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights into the Antibacterial Effect of Nano- and Micro-Materials

edited by

Krasimir Vasilev

and

Vi Khanh Truong

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2150 | Submission Open

Keywords: antibacterial coatings; biomaterials; medical devices; antimicrobial resistance; nanomedicine

(This special issue belongs to the Section Materials Science)

Molecular Associations Between Adipose Tissue and Diseases

edited by

Roberto Cannataro

Erika Cione

and

Maria Cristina Caroleo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2139 | Submission Open

Keywords: lipedema; adipose tissue; adipocyte; adipose organ; body fat; miRNA; ketogenic diet

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2130 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms and Functions of Extracellular Vesicles

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2091 | Submission Open

Keywords: extracellular vesicles; molecular mechanisms; biomarkers; liquid biopsy; cell-communication; cellular function; pathobiology; clinical

(This special issue belongs to the Section Molecular Biology)

Elucidating How Chondrocytes Maintain Cartilage Stability

edited by James A. Martin

submission deadline 20 Feb 2026 | 4 articles | Viewed by 2078 | Submission Open

Keywords: chondrocytes; articular cartilage; chondrogenesis; osteoarthritis; mechano-transduction; aging; extracellular matrix

(This special issue belongs to the Section Molecular Biology)

The Impact of Biomolecules on the Pathogenesis of Oral and Periodontal Diseases

edited by

Ujjal Kumar Bhawal

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2049 | Submission Open

Keywords: biomolecules; inflammatory mediators; enzymes; cytokines; dysbiosis; microbiome; genetic and epigenetic factors; oral and periodontal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Therapeutic Targets in Cardiometabolic Disorders

edited by Massimiliano M. Corsi Romanelli and

Pietro Formisano

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1967 | Submission Open

Keywords: atherosclerosis; angiotensin; endothelial cell; inflammation; biomarkers; gLP-1; sT-2

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1960 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1954 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

Protein Kinase in Disease, 2nd Edition

edited by

Manae Suzuki Kurokawa

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1945 | Submission Open

Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 20 Feb 2026 | 3 articles | Viewed by 1926 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Molecular Diagnosis and Treatment of Migraine

edited by

Fabiola Dach

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1876 | Submission Open

Keywords: migraine; pathophysiology; diagnostics; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Heart Failure: From Bench to Bedside

edited by

Nadia Aspromonte

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1858 | Submission Open

Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Pathogenesis and Treatment of Skin Cancer (2nd Edition)

edited by

Enrica Flori

Giorgia Cardinali

and

Vittoria Maresca

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1757 | Submission Open

Keywords: melanoma; squamous cell carcinoma; basal cell carcinoma; tumor microenvironment; epithelial– mesenchymal transition (EMT) process; ultraviolet radiation; oxidative stress; bioactive modulators; signal transduction pathways

(This special issue belongs to the Section Molecular Oncology)

Plant Metabolism and Natural Product Biosynthesis

edited by

Andrej Frolov

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1756 | Submission Open

Keywords: plant metabolism; natural product; biosynthesis; metabolomics; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Exploring the Genetics in Rare Diseases: A Genomic Odyssey

edited by

Klaus Brusgaard

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1738 | Submission Open

Keywords: novel discoveries in rare disorders; polygenic risk scores; mosaicism; protein interaction; tools utilized to engineer DNA; somatic variants; patient advocacy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Phytochemicals in Antioxidation, Antimicrobial, and Cytoprotective Properties

edited by

Mihaela Niculae

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1720 | Submission Open

Keywords: phytochemicals; antioxidant; antimicrobial; cytoprotective; in vitro screening; in vivo evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1692 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Diversity of Life: Light to Heavy Metal Coordination Compounds of Biological Relevance

edited by

Ivayla Pantcheva

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1681 | Submission Open

Keywords: coordination compounds; metal-based drugs; antimicrobial; anti-inflammatory; antiviral agents; cancer therapy; drug delivery systems

(This special issue belongs to the Section Biochemistry)

Developing Chiral Products: New Progression in Separation, Synthesis, and Application

edited by István Ilisz

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1676 | Submission Open

Keywords: chirality; enantioselective separations; chiral selector molecules; chiral stationary phases; chiral sensors; enantiorecognition; chiral separation mechanisms

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

New Advances in Cystinosis from Basic to Clinical Research

edited by Francesco Bellomo

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1650 | Submission Open

Keywords: cystinosis; kidney; Fanconi syndrome; muscles; eyes; autophagy; bioenergetics; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ruminant Physiology: Digestion, Metabolism, and Endocrine System

edited by Rui Hu

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1606 | Submission Open

Keywords: ruminant physiology; digestive health; metabolic regulation; endocrine signaling; rumen microbiome; nutrient partitioning; methane mitigation; epigenetic modulation; nutritional stress adaptation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Toxicological Impacts of Emerging Contaminants on Aquatic Organisms

edited by

Mohamed Hamed

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1566 | Submission Open

Keywords: aquatic toxicology; emerging contaminants; physiology and behavior; oxidative stress; antioxidant biomarkers; immunotoxicity; neuroendocrine toxicity; bioremediation; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Displaying special issue 1701-1750 on page 35 of 70.

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