New Advances in Cervical Cancer and Its Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 72
Special Issue Editors
Interests: vulvar cancer; cervical cancer; ovarian cancer
Interests: gynecological oncology; endometrial cancer; gynecological surgery; ovarian cancer; cervical cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Despite advances in primary and secondary prevention, cervical cancer remains a major global health concern, affecting millions of women. In recent decades, major advances have been achieved in understanding cervical cancer biology and oncogenesis. For over twenty years, persistent HPV infection has been understood to be a necessary precursor in the development of invasive cervical cancer. The implementation of screening programs, including Pap smears and HPV testing, has enabled the early detection of cervical abnormalities, supporting timely diagnosis and intervention. As a result, a growing number of cases are identified at early stages, with about 40% of patients diagnosed at childbearing age. Surgery, with or without radiotherapy or chemotherapy, is a viable option for small, localized tumors in the absence of sidewall or distant disease. Furthermore, growing evidence supports the efficacy and safety of fertility-sparing techniques as a viable treatment option for young women with early-stage cervical cancer who strongly wish to preserve their childbearing potential. Therefore, early detection and conservative treatment are crucial in improving outcomes and reducing disease burden and present a key opportunity to implement targeted interventions that could enhance survival and preserve quality of life. On the other hand, for patients with locally advanced/ metastatic or recurrent disease, it is crucial that we investigate different pharmacological regimens or combinations, including chemotherapy and radiotherapy. In the last decade, a range of pharmacological strategies have been investigated, such as immune checkpoint inhibitors, DNA damage repair inhibitors, and antibody–drug conjugates, with promising results. This Special Issue of IJMS will focus on recent advances in cervical cancer and its various treatments, aiming to optimize oncological tailored treatment by considering current clinical implications, balancing the disease stage with patient age and fertility preference, and future perspectives. We look forward to receiving your contributions.
Dr. Ilaria Cuccu
Dr. Violante Di Donato
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cervical cancer
- cervical cancer surgery
- fertility-sparing techniques
- targeted therapy
- immunotherapy
- immune checkpoint inhibitors
- DNA damage repair inhibitors
- antibody–drug conjugates
- precision medicine
- oncological outcomes
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
