Viral Vector-Mediated Genome Editing Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 112
Special Issue Editor
Interests: adenovirus vectors; genome editing; knock-in; inherited diseases; viral vectors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Genome editing therapy could offer totally novel cures for the various diseases for which no effective therapy is currently available. These diseases include mainly genetic disorders but also cancers and infectious diseases. Especially, new therapies using the knock-in technique have been desired because they could realize a complete cure for the whole life of patients. Virus vectors could become effective "drugs" in genome editing therapy, though efficiency of knock-in is still too low for successful therapy, and current vectors require extremely high costs, often exceeding one million USD for one dose. More studies and developments are needed and seriously desired in this field.
This Special Issue will focus on studies, developments, and applications of new genome-editing therapies using viral vectors. The vectors include AAV, lentivirus, and, especially, adenovirus. Basic and applied studies are in focus, but clinical research and survey studies are not suitable. Both articles and reviews are welcome. I hope that your contribution will promote the realization and generalization of genome editing therapy.
Prof. Dr. Izumu Saito
Guest Editor
Manuscript Submission Information
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Keywords
- genome editing
- adenovirus vector
- knock-in
- inherited disease
- viral vectors
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