Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 July 2025 | Viewed by 341
Special Issue Editor
2. Campus Uberlândia, Universidade de Uberaba (UNIUBE), Uberlândia 38055-500, Brazil
Interests: redox systems; oxidative stress; free radicals; antioxidants; redoxomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
“What moves life is a small electric current, held by the sun!”. This statement, attributed to Albert von Szent-Györgyi, 1937 Nobel Prize winner for Physiology/Medicine, for his research on the Krebs cycle and vitamin C, elegantly summarizes a principle applicable to any living organism, from bacteria to humans, passing through the biomes of all terrestrial, aquatic, and aerial ecosystems. In fact, all living organisms, in order to adapt and survive to various internal or external environmental challenges, use a common chemical mechanism: the transfer of electrons, in short, a small electric current. This mechanism is supported by an interspecies adaptive biochemical system, highly conserved throughout evolution, i.e., the redox system. In its elementary mode of operation, the redox system, appropriately stimulated, exploits the passage of single electrons between an oxidizing chemical species, a biological target and a reducing/antioxidant species to modulate signal and/or defense pathways; this allows the living organism to react and adapt to various biotic and abiotic stressors. The redox system is also an important link between the two components, macro-symbiotic and micro-symbiotic, of all holobionts (men, plants, and animals) wherever distributed (soil, water, and air). From the perspective of the “ONE HEALTH” concept, a well-trained redox system, capable of providing suitable responses to various environmental challenges, will be able to maintain the well-being of any life form in the soil, water, and atmosphere: oxidative eu-stress, to be favored or, at least, not opposed. Conversely, a malfunctioning redox system will increase the risk of premature aging and disease: oxidative distress, to be identified, prevented, and treated. The purpose of this Special Issue is to stimulate research and the publication of articles aimed at better understanding the functioning of the redox system as an adaptive biochemical system transversal to all living organisms, so as to be able to modulate it adequately in the event of disease. Lifestyle, nutraceuticals, and probiotics must become key words for the well-being of any terrestrial, aqueous, or atmospheric holobiont to face the great threats to which our biosphere is exposed today.
Dr. Eugenio Luigi Iorio
Guest Editor
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Keywords
- redox systems
- aging and disease
- nutraceuticals
- probiotics
- animals
- plants
- aquatic ecosystems
- microbiomes
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