Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 661
Special Issue Editor
Interests: biomaterials; bone regeneration; bioengineering; biomedical engineering
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the physiological mechanisms of bone biology and bone tissue. Bone is a crucial tissue that is involved in a variety of metabolic tasks, including body support, organ protection, mineral deposit, and hematological functions. It has recently been shown that bone tissue has endocrine functions, releasing hormonally active compounds, such as osteocalcin. Bone tissue is constantly rebuilt via the bone remodeling process, which involves osteoclast-mediated bone resorption followed by osteoblast-mediated bone synthesis. The discovery of the processes underlying the pathophysiology of metabolic bone disorders continues to be a major research focus, drawing experts from all medical fields. Furthermore, biomaterial-mediated immune responses regulate fundamental bone processes, such as osteogenesis, osteoclastogenesis, and inflammation, demonstrating their importance in biomedical applications.
This Special Issue, “Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition”, aims to provide new knowledge on the regulatory mechanisms of bone regeneration by focusing on the biological interplay between stem cell differentiation, the immune system, and the involvement of novel materials.
Potential topics of interest for this Special Issue include the following:
- Mechanisms of bone regeneration;
- Innovative materials for bone regeneration;
- Future bone tissue engineering applications;
- Pathophysiology of metabolic bone diseases;
- Role and use of stem cells in bone regeneration and repair;
- Crosstalk between bone cells and immune cells;
- Endocrine activities of bone tissue.
We welcome the submission of original articles, reviews, and communications by experts in this field. This Special Issue is supervised by Prof. Giovanna Iezzi, who is assisted by our Topical Advisory Panel Members—Dr. Emira D’Amico and Dr. Tania Vanessa Pierfelice (University of Chieti-Pescara).
Volume I of the Special Issue: “Molecular Studies of Bone Biology and Bone Tissue”
Prof. Dr. Giovanna Iezzi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bone
- stem cells
- immunomodulation
- biomaterials
- bone regeneration
- bone repair
- bone diseases
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