Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Oral Cancer: From Molecular Mechanisms to Therapeutics

edited by Diana Russo

submission deadline 30 May 2026 | Viewed by 8 | Submission Open

Keywords: oral cancer; molecular mechanisms; carcinogenesis; therapeutic strategies; biomarkers; immunotherapy; tumor microenvironment; drug resistance; precision medicine; head and neck oncology

(This special issue belongs to the Section Molecular Oncology)

Retinal Degeneration: From Pathophysiology to Therapeutic Approaches—4th Edition

edited by

Jan Wijnholds

submission deadline 30 May 2026 | Submission Open

Keywords: hereditary retinal disease; retinal inflammation; retinal gene augmentation; editing; optogenetics and splice modulation therapy; natural history studies of the retina; human iPSC-derived retina and retinal pigment epithelium; retinal iPSC-derived cell therapy; retinal pathology; pre- and clinical gene therapy; animal models for retinal dystrophy; retinal imaging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Decoding Parkinson’s: Molecular Symphonies and Dysregulated Pathways

edited by Hortensia Alonso-Navarro

submission deadline 30 May 2026 | Submission Open

Keywords: Parkinson’ s disease; neuropharmacology; movement disorders

(This special issue belongs to the Section Molecular Neurobiology)

Atherosclerosis: From Molecular Biology to Therapeutic Perspective: 7th Edition

edited by

Ida Daniela Perrotta

submission deadline 30 May 2026 | Submission Open

Keywords: atherosclerosis; vascular smooth muscle cells; inflammation; endothelium; cell senescence; apoptosis; lipid metabolism; oxidative stress; nitric oxide; exosomes; vascular calcification; cytokines; growth factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling Immunometabolism in Sepsis: From Cellular Reprogramming to Therapeutic Targets

edited by

Marcello Candelli

submission deadline 30 May 2026 | Submission Open

Keywords: sepsis; immunometabolism; metabolic reprogramming; cellular bioenergetics; innate and adaptive immunity; mitochondrial dysfunction; inflammatory signaling; metabolic biomarkers; therapeutic modulation; host– pathogen interactions

(This special issue belongs to the Section Molecular Immunology)

Recent Progress in Regenerative Therapy Using Blood-Derived Biomaterials: 2nd Edition

edited by

Tomoyuki Kawase

Takashi Ushiki

and Tomoharu Mochizuki

submission deadline 30 May 2026 | Submission Open

Keywords: blood-derived biomaterial; platelet-rich plasma; autologous protein solution; mechanism; platelet; coagulation

(This special issue belongs to the Section Materials Science)

Design and Application of Biocatalysts: Emerging Advances in Enzyme Technology

edited by

Salvadora Ortega-Requena

submission deadline 30 May 2026 | Submission Open

Keywords: biocatalysis; enzyme engineering; green chemistry; directed evolution; computational design; industrial enzymes; nano-biocatalysts

(This special issue belongs to the Section Biochemistry)

Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 3rd Edition

edited by

Marianna Lauricella

and

Antonella D'Anneo

submission deadline 31 May 2026 | 4 articles | Viewed by 22729 | Submission Open

Keywords: obesity; adipokines; obesogens; genetic predisposition; natural/synthetic compounds; cardiovascular disorders; type II diabetes; non-alcoholic fatty liver disease; cancer

(This special issue belongs to the Section Molecular Pharmacology)

State-of-the-Art Molecular Oncology in Brazil, 3rd Edition

edited by

Tiago Rodrigues

and

Roger Chammas

submission deadline 31 May 2026 | 7 articles | Viewed by 14320 | Submission Open

Keywords: apoptosis; autophagy; calcium; cancer; cell death; chemotherapy; metabolism; mitochondria; drug resistance; oxidative stress

(This special issue belongs to the Section Molecular Oncology)

Molecular and Translational Research on Bone Tumors, 2nd Edition

edited by

Michela Rossi

and

Andrea Del Fattore

submission deadline 31 May 2026 | 2 articles | Viewed by 12682 | Submission Open

Keywords: primary bone tumours; metastatic bone tumour; therapy; biomarkers; epigenetic factors; immune-oncology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Pulmonary Hypertension and Interstitial Lung Diseases: Mechanisms and Treatments

edited by

Katarzyna B. Lewandowska

and

Monika Szturmowicz

submission deadline 31 May 2026 | 2 articles | Viewed by 1386 | Submission Open

Keywords: pulmonary hypertension; interstitial lung disease; lung fibrosis; pulmonary hemodynamics; pulmonary function testing; pathogenesis; prognosis; survival; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Future of Drug Discovery and Development, 2nd Edition

edited by

William C. (Trey) Putnam

submission deadline 31 May 2026 | Viewed by 425 | Submission Open

Keywords: drug discovery; drug development; biotechnology; target identification; target validation; regulatory affairs; regulatory sciences; drug commercialization; pharmaceutical market access; drug screening; novel nonclinical models/approaches; advanced manufacturing; continuous manufacturing; process analytical technology; adaptive clinical trials; in silico laboratory and clinical development; rolling submissions; accelerated approvals; real-world evidence

(This special issue belongs to the Section Molecular Pharmacology)

Microbiota-Mediated Regulation of Stem Cells in Cancer Initiation, Progression, and Treatment Response

edited by

Ciro Gargiulo Isacco

submission deadline 31 May 2026 | Viewed by 340 | Submission Open

Keywords: microbiota stem cell cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Viral Infections and Viral Pathogenesis

edited by

Shymaa E. Bilasy

submission deadline 31 May 2026 | Viewed by 92 | Submission Open

Keywords: viral pathogenesis; viral– host interactions; viral persistence; long COVID; molecular virology; immune dysregulation; diagnosis; vaccines; oncoviruses; antiviral and gene therapy

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Natural Products: Redox Balance, Inflammation Control, and Apoptosis Modulation

edited by Rosanna Avola

submission deadline 31 May 2026 | Viewed by 77 | Submission Open

Keywords: natural antioxidants; inflammation; apoptosis; bioactive natural products; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular and Molecular Mechanisms of Neuroinflammation

edited by

Maria Anttonietta Panaro

submission deadline 31 May 2026 | Viewed by 74 | Submission Open

Keywords: neuroinflammation; astrocytes; microglia; CNS; cytokines; brain; diseases; immune response

(This special issue belongs to the Section Molecular Neurobiology)

Advances in the Pharmacology of Depression and Mood Disorders

edited by

Guillaume Lucas

submission deadline 31 May 2026 | Viewed by 72 | Submission Open

Keywords: new antidepressants; rapid antidepressant action; ketamine in depression; glutamatergic antidepressants; psychedelics in depression; 5-HT receptors as targets for antidepressant research; neu-roplasticity and antidepressant action

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Systems Mechanisms of Neural Circuit Function and Plasticity

edited by

Hyunjung Oh

submission deadline 31 May 2026 | Viewed by 63 | Submission Open

Keywords: neural circuits; neuroplasticity; synaptic organization; brain aging; mood disorders; neurodegenerative disorders; cognitive function

(This special issue belongs to the Section Molecular Neurobiology)

Bioactive Molecules in Infection and Toxicity: Antimicrobial Peptides and Drug-Induced Damage in Disease Models

edited by

Oleksii Skorokhod

submission deadline 31 May 2026 | 1 articles | Viewed by 63 | Submission Open

Keywords: antimicrobial peptides (AMPs); infectious diseases; drug-induced toxicity; disease models; therapeutic strategies; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Microorganisms and Invertebrates in Molecular Dialogue: Mechanisms, Dynamics, and Applications

edited by

Monika Mioduchowska

submission deadline 31 May 2026 | Viewed by 60 | Submission Open

Keywords: microorganism– invertebrate interactions; symbiosis; stress tolerance; co-evolution; omics approaches; biotechnological applications

(This special issue belongs to the Section Molecular Microbiology)

Physiological and Molecular Responses of Plants to Drought Stress

edited by

Muhammad Waseem

submission deadline 31 May 2026 | Viewed by 53 | Submission Open

Keywords: drought stress; photosynthesis; stomatal regulation; signal transduction; phytohormones; anti-oxidants

(This special issue belongs to the Section Molecular Plant Sciences)

Functional Materials for Biomedical Applications and Uses

edited by

Magdalena Laskowska

submission deadline 31 May 2026 | Viewed by 51 | Submission Open

Keywords: functional materials; nanomaterials; biomedical applications; molecular engineering

(This special issue belongs to the Section Materials Science)

Genetic and Molecular Insights into Aging in Vertebrate Models

edited by

Antonio Palladino

submission deadline 31 May 2026 | Viewed by 39 | Submission Open

Keywords: aging; vertebrate models; molecular mechanisms; cellular senescence; translational medicine

(This special issue belongs to the Section Molecular Biology)

Platelet-Mediated Immune Regulation in Cancer

edited by

Bennett D. Elzey

submission deadline 31 May 2026 | Viewed by 36 | Submission Open

Keywords: platelets; tumor immunity; megakaryocyte; immunotherapy; lymphocytes; microvesicles; immune suppression; metastasis

(This special issue belongs to the Section Molecular Immunology)

Cryo-EM and Cryo-Tomography in Macromolecular Structure Analysis

edited by

R. Holland Cheng

submission deadline 31 May 2026 | Viewed by 35 | Submission Open

Keywords: macromolecular structure; precision nanomedicine; cryo-electron microscopy (cryo-EM); cryo-electron tomography (cryo-ET); viral capsids; AI/ML in structural analysis; time-resolved imaging; nanoparticle delivery; in-cell tomography; structural dynamics; molecular mechanisms; protein complexes; membrane proteins; macromolecular assemblies; conformational changes; integrative structural biology; cellular structural biology; drug delivery systems; therapeutic design

(This special issue belongs to the Section Macromolecules)

The Role of Ferroptosis in Cancer Biology and Therapy

edited by Alessandra Di Paola and Elvira Pota

submission deadline 31 May 2026 | Viewed by 33 | Submission Open

Keywords: ferroptosis; cancer biology; tumor microenvironment; therapeutic targeting; anticancer immunity; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Metabolic Alterations in Health and Disease: From Molecular Mechanisms to Biomarkers in Clinical Applications

edited by

Ramona D'Amico

and

Rosalba Siracusa

submission deadline 31 May 2026 | Viewed by 27 | Submission Open

Keywords: metabolic syndrome; diabetes; oxidative stress; cellular metabolism; biomarkers; molecular pathways; metabolic disorders

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Exploring the Functional Activity of Natural Products

edited by

Antonio Speciale

submission deadline 31 May 2026 | Viewed by 24 | Submission Open

Keywords: natural products; natural drug discovery; bioactive compounds; biological activity; molecular mechanisms; anti-inflammatory activity; anticancer properties; therapeutic potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Human Virome and Emerging Viruses: Characterization, Interactions, and Molecular Insights

edited by

Luigi Rosa

and

Pietro Giorgio Spezia

submission deadline 31 May 2026 | Viewed by 21 | Submission Open

Keywords: human virome; molecular virology; functional virology; metagenomics; virus– host interactions; immune modulation; pseudovirus assays; antiviral screening; omics integration; molecular immunology

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Computational Innovations in Forensic Genetics: From Degraded DNA to Predictive Models

edited by Eugenio Alladio and

Elena Pilli

submission deadline 31 May 2026 | Viewed by 19 | Submission Open

Keywords: degraded DNA; low-template DNA; molecular forensics; NGS; machine learning; deep learning; chemometrics; data integration; predictive models; forensic applications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Crosstalk in Allergy, Barrier Dysfunction, and Asthma

edited by

Elisa Boni

submission deadline 31 May 2026 | Viewed by 18 | Submission Open

Keywords: barrier dysfunction; asthma; allergy; molecular pathways; molecular crosstalks

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology, Genetics, Diagnosis, Management and Therapy of Dermatological Diseases

edited by

Elisa Molinelli

and Corrado Tagliati

submission deadline 31 May 2026 | Viewed by 16 | Submission Open

Keywords: genodermatoses; hydradenitis suppurativa; inflammatory dermatoses; metabolic disorders; infections; esthetic medicine; neoplastic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Biomarkers in Cardiovascular Risk Assessment and Myocardial Injury

edited by Beatriz Martín-Carro

submission deadline 31 May 2026 | Viewed by 14 | Submission Open

Keywords: cardiovascular disease; myocardial injury; heart failure; biomarkers; risk stratification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetics and Molecular Mechanisms of Cancer Immunotherapy Response

edited by

Javier Oliver

submission deadline 31 May 2026 | Viewed by 11 | Submission Open

Keywords: cancer immunotherapy; genetic biomarkers; immunogenomics; immune checkpoint inhibitors; resistance mechanisms; precision oncology; germline variants; molecular response prediction; immune-related adverse events

(This special issue belongs to the Section Molecular Oncology)

Molecular Research of Gastrointestinal Disease, 3rd Edition

edited by

Ainsley Robinson

and

Kulmira Nurgali

submission deadline 31 May 2026 | Viewed by 10 | Submission Open

Keywords: gastrointestinal health; gastrointestinal disorders; gastrointestinal disease; gastrointestinal homeostasis; molecular targets; mechanisms; pathways; molecular markers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Treatment for Bacterial Infections: 2nd Edition

edited by Janusz Madaj

submission deadline 31 May 2026 | Viewed by 10 | Submission Open

Keywords: bacterial infection; antibiotic-resistant bacteria; new agents in the treatment of bacterial infections; optimization of the use of already registered drugs; single antibacterial agents; combined antibacterial agents; new drug forms

(This special issue belongs to the Section Molecular Pharmacology)

Signaling and Stress Adaptation in Plants: 2nd Edition

edited by

Kangdi Hu

submission deadline 31 May 2026 | Viewed by 7 | Submission Open

Keywords: plants; environmental stress; stress signaling; reactive oxygen/nitrogen species; calcium; protein kinases; stress resistance; adaptive mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Discovery of Plant-Derived Compounds and Their Immunomodulatory Applications

edited by

Jun Jiang

submission deadline 31 May 2026 | Viewed by 5 | Submission Open

Keywords: plant-derived compounds; immunomodulators; phytochemicals; immune signaling; natural products; autoimmune diseases; intestinal flora; in vitro evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Theoretical and Computational Chemistry: New Insights into Molecular Modeling and Design

edited by

Alejandro Morales-Bayuelo

and

Cleber Melo-Filho

submission deadline 31 May 2026 | Submission Open

Keywords: theoretical chemistry; computational chemistry; molecular modeling; quantum chemistry; density functional theory (DFT); molecular dynamics (MD); molecular structure prediction; reaction mechanism modeling

(This special issue belongs to the Section Molecular Informatics)

Foodomics: Challenges and Opportunities for a Sustainable Future

edited by

Mónica Carrera

submission deadline 31 May 2026 | Submission Open

Keywords: foodomics; sustainable food systems; omics; food quality; safety and innovation; green and circular technologies; personalized nutrition

(This special issue belongs to the Section Biochemistry)

Molecular Research in Gynecological Cancers

edited by

David B. Alexander

submission deadline 31 May 2026 | Submission Open

Keywords: malignant gynecological diseases; screening for gynecological cancers; benign gynecological conditions; screening for benign gynecological diseases; endometriosis; polycystic ovaries syndrome; ovarian cysts; uterine fibroids; leiomyomas; adenomyosis; pelvic inflammatory disease; vaginitis; vaginal dysbiosis; treatment targets for gynecological diseases

(This special issue belongs to the Section Molecular Oncology)

Targeted Molecular Radio-Immuno-Theranostics: From Cancer to other Human Diseases—in Honor of Prof. Dr. Otmar Dieter Wiestler

edited by Michael Philipp Bachmann and Holger Stephan

submission deadline 31 May 2026 | Submission Open

Keywords: molecular diagnostics; radiotherapy; immunotherapy; endoradionuclide therapy; radiodiagnostics; radio-immuno-theranostics; radionuclides; PET/SPECT imaging; nanomaterials; chelators; chimeric antigen receptors (CARs); adapter CAR T cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovations in Analytical Chemistry for Environmental and Food Safety: Methodologies and Molecular Insights

edited by

Cosima Damiana Calvano

and

Francesco Longobardi

submission deadline 31 May 2026 | Submission Open

Keywords: innovative sample preparation; food quality and safety; advanced analytical techniques; risk assessment

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Latest Advances on Natural Bioactive Molecules and Polysaccharides

edited by Loredana Marcolongo

submission deadline 31 May 2026 | Submission Open

Keywords: natural products; bioactive compounds; polysaccharides; extraction technologies; bioprocesses; value-added products; one-health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Neurological Mechanisms of Action of Natural Products

edited by Damião Pergentino De Sousa

submission deadline 31 May 2026 | Submission Open

Keywords: Alzheimer's disease; Parkinson's disease; epilepsy; dementia; pain; essential oils; medicinal plants; alkaloids; flavonoids; natural products

(This special issue belongs to the Section Molecular Neurobiology)

Synthesis and Activity Studies of Anticancer Compounds

edited by

Agata Pacuła-Miszewska

submission deadline 31 May 2026 | Submission Open

Keywords: anticancer agents; structure-activity relationship; cytotoxicity mechanisms; medicinal chemistry; drug design

(This special issue belongs to the Section Molecular Pharmacology)

Individualised Therapies for Rare Disorders

edited by Paul Gissen

submission deadline 31 May 2026 | Submission Open

Keywords: individualised therapies; personalised medicine; rare diseases; omics; gene therapy; molecular pathways; mechanistic discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Functions and Mechanisms of Hepatic Cancer-Associated Genes and miRNAs

edited by Eleni-Myrto Trifylli

submission deadline 31 May 2026 | Submission Open

Keywords: microRNAs (miRNAs); hepatocellular carcinoma (HCC); hepatic cancer; extracellular vesicles; noncoding RNAs; circular RNAs (circRNAs); gene regulation; epigenetics; drug resistance; biomarkers

(This special issue belongs to the Section Molecular Oncology)

Eosinophils: Function and Related Disorders

edited by Giulia Costanzo

submission deadline 31 May 2026 | Submission Open

Keywords: eosinophils; polymorphonuclear cells; interleukin; cytotoxic proteins; host defense; tissue remodeling; dysregulation; eosinophilic disorders; therapeutics

(This special issue belongs to the Section Biochemistry)

Genetic Variations in Human Diseases: 3rd Edition

edited by

Paweł Niemiec

submission deadline 31 May 2026 | Submission Open

Keywords: genetic polymorphism; gene– gene interaction; gene– environment interaction; monogenic disorder; mutation phenotype; quantitative trait locus; family-based study; cohort study; association study

(This special issue belongs to the Section Molecular Genetics and Genomics)

Displaying special issue 3101-3150 on page 63 of 67.

Go to page 61 62 63 64 65

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI