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Molecular and Systems Mechanisms of Neural Circuit Function and Plasticity

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 May 2026

Special Issue Editor


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Guest Editor
Department of BioNano Technology, Gachon University, Seongnam-si, Gyeonggi-do, Republic of Korea
Interests: neural; psychiatric disorders

Special Issue Information

Dear Colleagues,

Neural micro-circuits are fundamental computational units of the brain, translating biochemical and electrical signals into coherent cognitive and behavioral outputs. In recent years, remarkable progress in molecular imaging, electrophysiology, and multi-omics approaches has deepened our understanding of how circuit organization and plasticity are shaped by genetic, metabolic, and environmental factors. However, how these mechanisms collectively sustain brain function or conversely lead to dysfunction in brain disorders and during aging remains largely unresolved.

This Special Issue, “Molecular and Systems Mechanisms of Neural Circuit Function and Plasticity”, aims to highlight emerging insights into the organization and modulation of neural circuits across molecular, cellular, and systems levels. We welcome original research and review articles addressing circuit plasticity, neuromodulation, proteomic and metabolic regulation, and integrative or computational approaches that bridge molecular mechanisms with cognition and behavior.

Dr. Hyunjung Oh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • neural circuits
  • neuroplasticity
  • synaptic organization
  • brain aging
  • mood disorders
  • neurodegenerative disorders
  • cognitive function

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Published Papers

This special issue is now open for submission.
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