Genetics and Molecular Mechanisms of Cancer Immunotherapy Response
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 1
Special Issue Editor
2. Instituto de Investigación Biomédica de Málaga (IBIMA Plataforma BIONAND), Severo Ochoa 35, 29590 Málaga, Spain
Interests: precision medicine; pharmacogenetics; cancer pharmacogenomics; genetic variation and drug response; treatment toxicity prediction; personalized oncology therapy; biomarkers for treatment optimization; genotype-guided cancer treatment strategies
Special Issue Information
Dear Colleagues,
This Special Issue invites contributions that explore the molecular and genetic foundations underlying the response to cancer immunotherapy. As immune checkpoint inhibitors and related therapies transform oncology, understanding the genomic and immunogenetic landscapes is critical for unravelling individual variability in therapeutic efficacy and resistance. We welcome submissions that offer novel insights into the mechanisms by which germline and somatic variants or functional genomics shape the outcomes of immunotherapy. Studies leveraging multi-omics, biomarker discovery, experimental models and integrated molecular analysis are especially encouraged. We invite research combining clinical data with robust molecular or biomolecular experiments. Reviews synthesising advances in this field and proposing future research directions are also welcome.
This Special Issue aims to foster cross-disciplinary dialogue and accelerate discoveries at the frontiers of cancer immunogenomics.
Dr. Javier Oliver
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- cancer immunotherapy
- genetic biomarkers
- immunogenomics
- immune checkpoint inhibitors
- resistance mechanisms
- precision oncology
- germline variants
- molecular response prediction
- immune-related adverse events
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