Synthesis and Activity Studies of Anticancer Compounds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 May 2026
Special Issue Editor
Interests: organoselenium compounds; organic synthesis; medicinal chemistry; drug design and development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The versatility of factors that can influence the outcome of oncological treatment, e.g., time of detection, the nature of cancer cells, genetic mutations, and the patient's health condition, positions malignant tumours as the leading cause of death worldwide. The search for potent, selective, and clinically promising anticancer agents is one of the most active areas in medicinal chemistry and pharmaceutical science. Efforts are undertaken to construct structurally diverse scaffolds (e.g., small molecules, natural product derivatives, and metal complexes), evaluate the structure–activity relationship, to identify how specific functional groups or stereochemistry influence cytotoxicity, and explore the specific mechanisms of action including targets and pathways, such as apoptosis induction, cell–cycle regulation, kinase inhibition, and modulation of redox balance.
This Special Issue is supervised by Dr. Agata Pacuła-Miszewska and assisted by Dr. Magdalena Obieziurska-Fabisiak. This Special Issue aims at highlighting recent advances in the design, chemical modification, and biological evaluation of molecules that may serve as potential next-generation chemotherapeutics.
Dr. Agata Pacuła-Miszewska
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- anticancer agents
- structure-activity relationship
- cytotoxicity mechanisms
- medicinal chemistry
- drug design
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