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Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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BCMA-Directed CAR-T Therapy in Relapsed or Refractory Multiple Myeloma

edited by Al-Ola A. Abdallah

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2744 | Submission Open

Keywords: BCMA-directed CAR-T therapy; multiple myeloma; relapsed multiple myeloma; refractory multiple myeloma; B-cell maturation antigen; immunotherapy; treatment outcomes

(This special issue belongs to the Section Hematology)

Recent Advances in Immune Checkpoint Inhibition and Antibody Drug Conjugates in Urothelial Carcinoma

edited by Qian Janie Qin

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2612 | Submission Open

Keywords: immune checkpoint inhibition; antibody drug conjugates; urothelial carcinoma; therapeutic combinations; biomarkers; resistance mechanisms; treatment efficacy; cancer immunotherapy

(This special issue belongs to the Section Genitourinary Oncology)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1306 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

Therapeutic Advances in Cystectomy for Bladder Cancer

edited by Saum B. Ghodoussipour

submission deadline 30 Jun 2026 | Viewed by 373 | Submission Open

Keywords: bladder cancer; cystectomy; therapeutic advances; surgical techniques; personalized treatment

(This special issue belongs to the Section Genitourinary Oncology)

PD-1 and PD-L1 in Cancer Immunotherapy

edited by

Aleksandar Obradovic

submission deadline 30 Jun 2026 | Viewed by 309 | Submission Open

Keywords: PD-1; PD-L1; cancer immunotherapy; immune checkpoint inhibitors; resistance mechanisms; combination therapies

Advancing Precision Medicine in Hepatocellular Carcinoma: The Comprehensive Role of Liquid Biopsy

edited by

Amy K. Kim

submission deadline 30 Jun 2026 | Viewed by 260 | Submission Open

Keywords: circulating tumor cells; hepatocellular carcinoma; precision medicine; tumor heterogeneity; early diagnosis; prognosis; personalized treatment

(This special issue belongs to the Section Cell Therapy)

Prevention, Early Detection and Management of Skin Cancer

edited by

Patricia Tai

and

Kurian Joseph

submission deadline 30 Jun 2026 | Viewed by 251 | Submission Open

Keywords: skin cancer; dermato-oncology; cutaneous oncology; melanoma; non-melanomatous skin cancers; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; sebaceous carcinoma and other adnexal carcinomas; prevention and detection; treatment; biomarkers; immunotherapy and radiotherapy; precision medicine; UV radiation; surgery; targeted therapies

Recent Advances in Artificial Intelligence-Based Approaches for Breast Cancer

edited by

Ashirbani Saha

submission deadline 30 Jun 2026 | Viewed by 187 | Submission Open

Keywords: breast cancer; artificial intelligence; multimodal data; breast cancer datasets; AI model validation; benchmarking; literature appraisal; explainable AI for breast cancer; personalized medicine; generative AI for breast cancer

(This special issue belongs to the Section Breast Cancer)

Pain and Symptom Management in Cancer Patients

edited by Lynn R. Gauthier

submission deadline 30 Jun 2026 | Viewed by 181 | Submission Open

Keywords: cancer patients; pain management; symptom management; supportive care

Clinical Management of Lung Cancer Brain Metastases

edited by Shrinivas Rathod

submission deadline 30 Jun 2026 | Viewed by 172 | Submission Open

Keywords: lung cancer brain metastases; clinical management; radiotherapy techniques; targeted therapy; immunotherapy; multidisciplinary management; clinical trials

Targeting KRAS in Lung Cancer: Current Status and Future Directions

edited by Sally Lau

submission deadline 30 Jun 2026 | Viewed by 144 | Submission Open

Keywords: KRAS mutations; non-small cell lung cancer; targeted therapy; KRAS G12C inhibitors; translational research; combination therapy; clinical outcomes

(This special issue belongs to the Section Thoracic Oncology)

Recent Advancements in the Surgical Treatment of Brain Tumors—2nd Edition

edited by

Patrick Schuss

and Florian Gessler

submission deadline 30 Jun 2026 | Viewed by 135 | Submission Open

Keywords: brain tumors; intraoperative imaging; supramarginal resection; fluorescence-guided surgery; awake craniotomy; complication management; neurooncology; functional mapping; neuronavigation; intraoperative radiotherapy

(This special issue belongs to the Section Neuro-Oncology)

From Innovation to Impact: Age-Adaptive Oncology for Just and Precision-Driven Care

edited by Tanyanika Phillips

submission deadline 30 Jun 2026 | Viewed by 122 | Submission Open

Keywords: age-adaptive; oncology; older adults; aging; cancer; precision medicine; biological aging; functional aging; accelerated aging; biomarkers; therapeutics

(This special issue belongs to the Section Palliative and Supportive Care)

Transforming Pancreatic Cancer Treatment: Innovations in Molecular Diagnostics and Treatment Advances

edited by Nicola Normanno,

Michele Zanoni

and

Ilario Giovanni Rapposelli

submission deadline 30 Jun 2026 | Viewed by 114 | Submission Open

Keywords: pancreatic cancer; liquid biopsy; organoids; therapy resistance; predictive biomarkers

(This special issue belongs to the Section Oncology Biomarkers)

2nd Edition: Allogeneic Stem Cell Transplantation: Does the Conditioning Regimen Intensity Still Matter?

edited by Imran Ahmad

submission deadline 30 Jun 2026 | Viewed by 87 | Submission Open

Keywords: conditioning; preparative; regimen; allogeneic; hematopoietic; transplantation; myeloablative; nonmyeloablative; reduced

(This special issue belongs to the Section Hematology)

The Role of Targeted Therapy in Head and Neck Cancers

edited by

Rikki A.M. Brown

submission deadline 30 Jun 2026 | Viewed by 86 | Submission Open

Keywords: cancer; head and neck squamous cell carcinoma (HNSCC); targeted therapy; molecular drug targets; cancer biomarkers; personalized medicine; resistance mechanisms; combination therapies; translation oncology

(This special issue belongs to the Section Head and Neck Oncology)

Deep Insights into Acute Myeloid Leukemia: Molecular Targets and Evolving Treatment Paradigms

edited by

Serena Travaglini

submission deadline 30 Jun 2026 | Viewed by 78 | Submission Open

Keywords: acute myeloid leukemia (AML); molecular targets; targeted therapy; treatment resistance; precision medicine; immunotherapy; multi-omics; relapsed/refractory leukemia; therapeutic strategies

(This special issue belongs to the Section Hematology)

Advances in Targeted Therapies and Pharmacogenomics of Leukemia

edited by Nicolas N Nassar

submission deadline 30 Jun 2026 | Viewed by 74 | Submission Open

Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment

Brain Metastases: Biomarkers, Diagnosis, Treatment, Prognosis and Survival

edited by Katarzyna Jerzak

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: brain metastases; biomarkers; diagnosis and imaging; targeted and immunotherapy; prognosis and survival

(This special issue belongs to the Section Neuro-Oncology)

Molecular Integrative Genomics in Cancer

edited by

Muhammad Kibriya

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1394 | Submission Open

Keywords: somatic mutation; cytogenetic abnormality; amplification; deletion; gene fusion; MSI; methylation; liquid biopsy; cell-free DNA; gene– environment interaction; targeted therapy; precision medicine

Combined Therapies for Hepatocellular Carcinoma

edited by

Hooman Yarmohammadi

submission deadline 20 Jul 2026 | 3 articles | Viewed by 9307 | Submission Open

Keywords: hepatocellular carcinoma; combined therapies; immunotherapy; locoregional therapy; external beam radiation

(This special issue belongs to the Section Gastrointestinal Oncology)

Unveiling the Economic Impact of Cancer Treatment

edited by

Stuart Peacock

submission deadline 20 Jul 2026 | Viewed by 130 | Submission Open

Keywords: financial toxicity; cost-effectiveness; health equity; cancer economics; value-based care; economic disparities; survi-vorship; policy interventions; global burden; healthcare access

(This special issue belongs to the Section Health Economics)

Thoracic Malignancies and Immunity: Advances, Challenges, and Future Directions of Immunotherapy

edited by Giacomo Cusumano

submission deadline 30 Jul 2026 | Viewed by 125 | Submission Open

Keywords: lung cancer (NSCLC and SCLC); malignant pleural mesothelioma; immune checkpoint inhibitors; biomarkers (PD-L1; TMB; ctDNA); tumor microenvironment & immune evasion; combination therapies (chemo-IO; IO-IO; radiotherapy); neoadjuvant and adjuvant immunotherapy; immune-related adverse events (irAEs); resistance mechanisms & re-challenge; real-world evidence & translational research

(This special issue belongs to the Section Thoracic Oncology)

Advances in Interventional Radiology for Oncological Management

edited by Alex L. Wallace and

Merve Ozen

submission deadline 31 Jul 2026 | Viewed by 139 | Submission Open

Keywords: interventional oncology; tumor ablation; embolization; image-guided therapy; personalized medicine; translational research; cancer care

Contrast-Enhanced Imaging for Breast Cancer Detection and Management

edited by Enida Bufi,

Alejandro Martin Sanchez

, Matteo Sammarra and Angela Bucaro

submission deadline 31 Jul 2026 | Viewed by 114 | Submission Open

Keywords: contrast-enhanced mammography (CEM); breast cancer imaging; dense breast tissue; dual-energy mammography; radiomics; artificial intelligence; iodinated contrast medium

(This special issue belongs to the Section Breast Cancer)

Recent Advances in Breast Reconstruction Following Cancer

edited by

Jing Zhang

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: prepectoral implant-based reconstruction; post-reconstruction radiation; mastectomy pattern; non-abdominal autologous-based breast reconstruction; breast reconstruction complication; patient-reported outcome; breast sensation; fat grafting; enhanced recovery after surgery (ERAS) protocols; oncoplastic breast reconstruction; lymphatic reconstruction

(This special issue belongs to the Section Breast Cancer)

Hope Amidst Challenges: Therapies for Relapsed/Refractory Multiple Myeloma

edited by

Martha L. Louzada

submission deadline 10 Aug 2026 | Viewed by 42 | Submission Open

Keywords: RRMM; quadruplet therapy; CART-cell; bispecific antibodies; antibody drug conjugates (ADC); minimal residual disease (MRD)

(This special issue belongs to the Section Hematology)

Glioblastoma: Symptoms, Causes, Treatment and Prognosis

edited by Giuseppe Lombardi and Alberto Bosio

submission deadline 30 Aug 2026 | Viewed by 51 | Submission Open

Keywords: glioblastoma; molecular biomarkers; targeted therapy; immunotherapy; imaging; tumor microenvironment; prognosis

(This special issue belongs to the Section Neuro-Oncology)

The Evolving Landscape of Precision Medicine in Radiation Oncology

edited by

Fernando Munoz

submission deadline 31 Aug 2026 | 2 articles | Viewed by 5064 | Submission Open

Keywords: biomarkers; genomics; precision medicine; transcriptomics; radiotherapy response prediction

Radiation Therapy and Targeted Therapies for Pancreatic Cancer

edited by Aswin Abraham

submission deadline 31 Aug 2026 | Viewed by 132 | Submission Open

Keywords: pancreatic cancer; radiation; chemo-radiation; SBRT; patterns of failure; radiobiology; radiation techniques; cell signaling; immunotherapy and radiation; targeted therapies

(This special issue belongs to the Section Gastrointestinal Oncology)

Glioblastoma: The Emerging Challenges in Rapidly Evolving Social Changes

edited by Andrea Talacchi and Andrea Pace

submission deadline 31 Aug 2026 | Viewed by 84 | Submission Open

Keywords: glioblastoma; glioma; social determinants; prognostic factors; clinical pathways; lifestyle; economic determinants; frailty; area deprivation; brain neoplasm; overall survival

(This special issue belongs to the Section Neuro-Oncology)

Advances in Implementation Science and Knowledge Mobilization for Cancer Control

edited by

Sarah Neil-Sztramko

submission deadline 31 Aug 2026 | Viewed by 73 | Submission Open

Keywords: evidence-based interventions; cancer control; cancer prevention; cancer treatment; survivorship; knowledge mobilization; implementation science

Treatment of High-Grade Glioma

edited by Chiara Valentini and Silvia Chiesa

submission deadline 31 Aug 2026 | Viewed by 73 | Submission Open

Keywords: high-grade glioma; treatment; surgery; radiation therapy; chemotherapy; targeted therapy; immunotherapy

(This special issue belongs to the Section Neuro-Oncology)

Advances in Endocrine Therapy for Breast Cancer

edited by

Sandeep Sehdev

, Arif Ali Awan and

Karen A. Gelmon

submission deadline 31 Aug 2026 | Viewed by 68 | Submission Open

Keywords: endocrine therapy; breast cancer; endocrine resistance; CDK 4/6 inhibitor; biomarkers; selective endocrine receptor degraders (SERDs)

(This special issue belongs to the Section Breast Cancer)

Emphasis on Cardiovascular Health from Cancer Therapy: Incidence, Mechanisms, and Management

edited by Brijesh D. Patel

submission deadline 10 Sep 2026 | Viewed by 17 | Submission Open

Keywords: cardiotoxicity; cancer therapy-related cardiac dysfunction (CTRCD); arrhythmia; cardiomyopathy; disparity; innovation; prevention

2nd Edition: Stereotactic Radiosurgery for Brain Tumors

edited by Dante Amelio,

Piera Navarria

and Giuseppe Minniti

submission deadline 15 Sep 2026 | Viewed by 96 | Submission Open

Keywords: stereotactic radiosurgery; gamma knife; cyber knife; particle therapy; brain tumors; skull base tumors

Pathways to Recovery and Resilience in Breast Cancer Survivorship

edited by Nazanin Derakhshan

submission deadline 30 Sep 2026 | 5 articles | Viewed by 19563 | Submission Open

Keywords: breast cancer; intervention; mixed methods; digital health; personalized care; AI; resilience; anxiety; depression; neuroscience

(This special issue belongs to the Section Psychosocial Oncology)

Systemic Therapy in Hepatocellular Carcinoma: Current Challenges and Future Directions

edited by Andrea Martini and

Alessandro Vitale

submission deadline 30 Sep 2026 | Viewed by 78 | Submission Open

Keywords: immunotherapy; conversion therapy; hepatocellular carcinoma; surgical therapy: transplantation

(This special issue belongs to the Section Gastrointestinal Oncology)

Evolving Role of Surgical Resection in Pancreatic Cancer

edited by Eran Sadot, Oran Zlotnik and

Nasser Abdul Halim

submission deadline 30 Sep 2026 | Viewed by 57 | Submission Open

Keywords: pancreatic cancer; surgical resection; pancreaticoduodenectomy; distal pancreatectomy; vascular resection; borderline resectable disease; neoadjuvant therapy; minimally invasive surgery; oncologic outcomes; prognostic factors

(This special issue belongs to the Section Surgical Oncology)

Liver Transplantation in Oncology: Perspectives on Medical and Surgical Aspects

edited by

Paul J. Gaglio

and Keri E. Lunsford

submission deadline 30 Sep 2026 | Viewed by 35 | Submission Open

Keywords: liver transplantation; hepatocellular carcinoma; cholangiocarcinoma; liver cancer surgery; loco-regional therapies; downstaging; adjunctive therapies; metastatic liver tumors; transplant eligibility; transplant outcomes

(This special issue belongs to the Section Surgical Oncology)

Treatment Strategies for Advanced Urothelial Carcinoma

edited by Manojkumar Bupathi

submission deadline 30 Sep 2026 | Viewed by 9 | Submission Open

Keywords: advanced urothelial carcinoma; metastatic bladder cancer; FGFR-targeted therapy; immune checkpoint inhibitors; PD-L1 expression; therapeutic sequencing; combination therapy; treatment resistance; clinical outcomes; personalized oncology

(This special issue belongs to the Section Genitourinary Oncology)

Behavioural Interventions and Patient-Centred Approaches in Skin Cancer

edited by

Ivan V. Litvinov

and

Sandra Peláez

submission deadline 31 Oct 2026 | Viewed by 91 | Submission Open

Keywords: patient-centred care; behavioural interventions; patient perspectives and emotions; self-management and treatment adherence; public health strategies

(This special issue belongs to the Section Dermato-Oncology)

Genomic and Molecular Profiling in Genitourinary Oncology: Shaping the Future of Diagnosis and Treatment

edited by

Ricardo Fernandes

and Lilian Hanna

submission deadline 31 Oct 2026 | Viewed by 83 | Submission Open

Keywords: genito-urinary malignancies; molecular profiling; genomics; biomarkers; targeted therapy; precision oncology; liquid biopsy; translational research

(This special issue belongs to the Section Genitourinary Oncology)

Clinical Progression and Treatment Outcome of Multiple Myeloma

edited by Guido Lancman, Alissa Visram and Rayan Kaedbey

submission deadline 15 Nov 2026 | 2 articles | Viewed by 5141 | Submission Open

Keywords: multiple myeloma; real-world predictors of response; sequencing; treatment selection; resistance mechanisms

(This special issue belongs to the Section Hematology)

Advances in Surgical Treatment of Children with Bone Tumors

edited by

Costantino Errani

and

Shinji Tsukamoto

submission deadline 15 Nov 2026 | Viewed by 347 | Submission Open

Keywords: bone tumors; children; limb salvage surgery; massive bone allograft; prosthetic reconstruction; vascu-larized fibula; massive bone autograft

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Advances in Thoracic Oncology: From Surgical Innovation to Outcome Optimization

edited by Silvia Novello and

Francesco Leo

submission deadline 30 Nov 2026 | Viewed by 42 | Submission Open

Keywords: lung cancer; multimodality treatment; thoracic surgery; target therapy; immunotherapy

(This special issue belongs to the Section Thoracic Oncology)

Advanced Research on Breast Cancer Genes in Cancers

edited by Andrea Eisen

submission deadline 31 Dec 2026 | 6 articles | Viewed by 7891 | Submission Open

Keywords: breast cancer genes; BRCA1/2 mutations; cancer genomics; targeted therapies; precision medicine; genetic counseling

(This special issue belongs to the Section Oncology Biomarkers)

Molecular and Epidemiological Insights into Skin Cancer

edited by

Ivan V. Litvinov

and

Sandra Peláez

submission deadline 31 Dec 2026 | Viewed by 100 | Submission Open

Keywords: skin cancer pathogenesis; molecular mechanisms; gene– environment interactions; epidemiology and risk factors; prevention and early detection

(This special issue belongs to the Section Dermato-Oncology)

U.S. Myeloma Innovations Research Collaborative (USMIRC) Collection

edited by Al-Ola A. Abdallah

submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open

Keywords: multiple myeloma; immunotherapy; cellular therapy; CAR-T; T-cell engagers; TCE; multispecifics; BCMA; GPRC5D; plasmacytoma

(This special issue belongs to the Section Hematology)

PSMA PET Use in Oncology: From Diagnosis to Implications for Different Treatment Options

edited by

Fernando Munoz

submission deadline 31 Dec 2026 | Viewed by 26 | Submission Open

Keywords: PSMA PET; prostate cancer; molecular imaging; treatment decision making; precision oncology

(This special issue belongs to the Section Genitourinary Oncology)

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