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Current Oncology
Special Issues
Recent Advances in Breast Reconstruction Following Cancer
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Recent Advances in Breast Reconstruction Following Cancer

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Breast Cancer".

Deadline for manuscript submissions: 31 January 2027 | Viewed by 1934

Editor

Dr. Jing Zhang

E-Mail Website
Guest Editor
Department of Surgery, Division of Plastics and Reconstructive Surgery, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada
Interests: microsurgical breast reconstruction; reconstruction post tumor ablation and trauma

Special Issue Information

Dear Colleagues,

With improved clinical outcomes and durable patient satisfaction, post-mastectomy breast reconstruction continues to experience an increasing trend worldwide. In this special edition, we aim to cover the recent advances in breast reconstruction. The revolution of mastectomy pattern and incision allows personalized, yet safe, immediate reconstruction. Although the new trend in implant-based reconstruction is prepectoral positioning, the prepectoral vs. subpectoral placement and the role of biological and synthetic meshes remain subjects of debate. The current concept regarding the safety of post-reconstruction radiation therapy, fat grafting, and restoration of breast sensation will be explored. The novelty of autologous-based reconstruction, such as optimization of tissue perfusion, minimization of donor site mobility, and flap selection, will be updated. We will explore the strategies of perioperative care for pain control and enhanced recovery, as well as treatment of chronic pain post-reconstruction. Long-term patient-reported outcomes of breast reconstruction and lymphatic reconstruction will be discussed. Furthermore, we would like to update the management of reconstruction failure and the need for revision surgery for symmetry. Lastly, the current concept and development of oncoplastic breast surgery in level III and IV will be presented.

Dr. Jing Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prepectoral implant-based reconstruction
  • post-reconstruction radiation
  • mastectomy pattern
  • non-abdominal autologous-based breast reconstruction
  • breast reconstruction complication
  • patient-reported outcome
  • breast sensation
  • fat grafting
  • enhanced recovery after surgery (ERAS) protocols
  • oncoplastic breast reconstruction
  • lymphatic reconstruction

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Published Papers (2 papers)

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16 pages, 941 KB  
Article
Oncoplastic Surgery Versus Lumpectomy: Analysis of Oncological Outcomes and Surgical Complications in 1290 Breast Cancer Patients
by Adolfo Alejandro Lopez Rios, Michael J. Stein, Angel Arnaout and Jing Zhang
Curr. Oncol. 2026, 33(3), 163; https://doi.org/10.3390/curroncol33030163 - 12 Mar 2026
Cited by 1 | Viewed by 1415
Abstract
This 12-year retrospective study compared oncoplastic breast-conserving surgery (OBCS) with lumpectomy without reconstruction (LNR) to evaluate surgical and oncological outcomes. OBCS combines tumour removal with tissue reshaping to preserve breast contour, but concerns about treatment delays and recurrence limit its use. Among 1880 [...] Read more.
This 12-year retrospective study compared oncoplastic breast-conserving surgery (OBCS) with lumpectomy without reconstruction (LNR) to evaluate surgical and oncological outcomes. OBCS combines tumour removal with tissue reshaping to preserve breast contour, but concerns about treatment delays and recurrence limit its use. Among 1880 patients reviewed between 2008 and 2020, 1290 met the inclusion criteria—307 (24%) underwent OBCS and 983 (76%) underwent LNR. Women receiving OBCS were younger (mean 56 vs. 61 years, p < 0.0001) with similar BMIs. OBCS was associated with a slightly longer time to radiotherapy (3.93 vs. 3.57 months, p = 0.01) and higher rates of minor complications such as wound infection (7.17% vs. 3.66%), dehiscence (4.89% vs. 0.92%), and fat necrosis (11.73% vs. 1.12%) (all p < 0.0001). There were no significant differences in positive margins, mastectomy conversion, recurrence, or disease-free survival. Despite a modest delay in adjuvant therapy and increased minor complications, OBCS demonstrated equivalent oncologic safety to standard lumpectomy. These findings support OBCS as a safe breast-conserving option that maintains esthetic outcomes without compromising cancer control, encouraging its broader use in appropriately selected patients. Full article
(This article belongs to the Special Issue Recent Advances in Breast Reconstruction Following Cancer)
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16 pages, 609 KB  
Systematic Review
Laparoscopically Harvested Pedicled Omental Flap in Immediate Unilateral Breast Reconstruction: A Systematic Review of Surgical Techniques and Clinical Outcomes
by Annie M. Wu, Surabi Thirugnanasampanthar and Muriel Brackstone
Curr. Oncol. 2026, 33(7), 410; https://doi.org/10.3390/curroncol33070410 - 9 Jul 2026
Abstract
Laparoscopically harvested pedicled omental flap (LHPOF) reconstruction is a minimally invasive autologous option for immediate breast reconstruction, but prior reviews have largely examined omental flaps broadly, combining open and laparoscopic harvests, free and pedicled transfers, and mixed reconstructive indications. This systematic review evaluated [...] Read more.
Laparoscopically harvested pedicled omental flap (LHPOF) reconstruction is a minimally invasive autologous option for immediate breast reconstruction, but prior reviews have largely examined omental flaps broadly, combining open and laparoscopic harvests, free and pedicled transfers, and mixed reconstructive indications. This systematic review evaluated operative characteristics, peri-operative complications, and esthetic outcomes following LHPOF after oncologic breast surgery. MEDLINE, Cochrane and Embase were searched without language or date restrictions, with backward citation searching of included studies. Eligible studies included female patients undergoing immediate unilateral breast reconstruction with LHPOF after mastectomy or BCS. Twenty-two studies published between 2001 and 2025 were included, representing 1869 patients. Operative techniques were broadly consistent, most commonly involving transverse-colon-first omental harvest, preservation of the right gastroepiploic vessels, and tunnelling from the inframammary fold toward the xiphoid. Reported complications included omental fat necrosis, partial flap loss, hematoma, infection, epigastric bulging, and incisional or tunnel-site hernia. Esthetic outcomes were generally favourable but assessed using heterogeneous methods. Current evidence suggests this technique is feasible in selected patients and may offer favourable esthetic outcomes with limited donor-site morbidity. However, prospective comparative studies with standardized reporting are needed to define optimal patient selection, long-term safety, and esthetic durability. Full article
(This article belongs to the Special Issue Recent Advances in Breast Reconstruction Following Cancer)
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