Treatment of High-Grade Glioma

Dear Colleagues,

High-grade glioma remains a significant challenge in oncology. Characterized by aggressive growth and poor prognosis, current treatment approaches are diverse yet often insufficient. Surgical resection is designed to remove as much of the tumor as possible, but complete excision is frequently hindered by the tumor's infiltrative nature. Radiation therapy and chemotherapy are important adjuvant treatments, yet they come with various side effects and show limited effectiveness in some patients.

Newer treatment modalities, such as targeted therapies and immunotherapies, are emerging, but their optimal use and long-term impacts are still being explored. Additionally, understanding the molecular and genetic characteristics of high-grade glioma is crucial in developing more personalized treatment strategies.

For this Special Issue, we welcome original research articles and reviews in the area of high-grade glioma treatment. We aim to explore new treatment strategies, evaluate existing treatments, and discuss the latest research findings in this field.

We look forward to receiving your contributions.

Dr. Chiara Valentini
Dr. Silvia Chiesa
Guest Editors

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