BCMA-Directed CAR-T Therapy in Relapsed or Refractory Multiple Myeloma
A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 194
Special Issue Editor
Interests: multiple myeloma; immuno-cellular therapies in multiple myeloma; drug-resistant multiple myeloma; drug-development in heavily treated relapse myeloma
Special Issue Information
Dear Colleagues,
Relapsed or refractory multiple myeloma poses a significant challenge in hematology. BCMA-directed CAR-T therapy has emerged as a promising treatment approach in such cases. This specialized immunotherapy targets the B-cell maturation antigen (BCMA) expressed on myeloma cells, providing a targeted and potentially curative option. However, challenges such as cytokine release syndrome and neurotoxicity persist, requiring careful patient monitoring and management. This Special Issue will explore the latest advancements, outcomes, and challenges in BCMA-directed CAR-T therapy for multiple myeloma, facilitating a deeper understanding of its potential in transforming the landscape of myeloma treatment.
We welcome original research articles and reviews focusing on mechanisms, clinical outcomes, and future directions in BCMA-directed CAR-T therapy.
I look forward to receiving your contributions.
Dr. Al-Ola A. Abdallah
Guest Editor
Manuscript Submission Information
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Keywords
- BCMA-directed CAR-T therapy
- multiple myeloma
- relapsed multiple myeloma
- refractory multiple myeloma
- B-cell maturation antigen
- immunotherapy
- treatment outcomes
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