Transforming Pancreatic Cancer Treatment: Innovations in Molecular Diagnostics and Treatment Advances
A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Oncology Biomarkers".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 34
Special Issue Editors
Interests: translational research; biomarkers; liquid biopsy; oncology
Special Issues, Collections and Topics in MDPI journals
Interests: 3D models; senescence; cancer; therapy resistance; metabolism; extracellular matrix (ECM)
Special Issues, Collections and Topics in MDPI journals
Interests: pancreatic cancer; hepatobiliary cancers; neoadjuvant therapy; targeted therapy; therapy resistance; predictive biomarkers; liquid biopsy
Special Issue Information
Dear Colleagues,
Pancreatic cancer is one of the most lethal malignancies, characterized by late diagnosis, high biological heterogeneity, and limited therapeutic options. In recent years, the integration of cutting-edge diagnostic technologies and multimodal treatment strategies has begun to reshape the clinical landscape. Molecular diagnostics are enabling precise tumor profiling and the identification of predictive biomarkers, fostering the development of targeted approaches, currently limited to a subset of patients. At the same time, liquid biopsy is emerging as a non-invasive and dynamic tool for real-time disease monitoring, offering opportunities for early detection of treatment resistance and personalization of therapeutic strategies. On the preclinical front, the establishment of innovative models such as patient-derived organoids and xenografts provides robust platforms to investigate molecular mechanisms and evaluate novel therapeutic interventions. These systems improve the translational value of preclinical research, accelerating the bench-to-bedside process and enhancing the clinical relevance of experimental findings.
This Special Issue aims to collect original research and review articles focused on advances in molecular diagnostics, treatment strategies, the clinical utility of liquid biopsy, and the role of preclinical models in therapeutic innovation. Together, these contributions will highlight emerging strategies that are transforming the management of pancreatic cancer and paving the way toward more effective and personalized treatments.
Dr. Nicola Normanno
Dr. Michele Zanoni
Dr. Ilario Giovanni Rapposelli
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pancreatic cancer
- liquid biopsy
- organoids
- therapy resistance
- predictive biomarkers
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