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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetics and Genomics Research of Autism Spectrum Disorders

edited by

Golder N. Wilson

submission deadline 31 Oct 2026 | Viewed by 279 | Submission Open

Keywords: autism; neurodevelopmental disorders; genomics; copy number variants; next-generation sequencing

(This special issue belongs to the Section Molecular Medicine)

Functional Genomics and Comparative Genomics Analysis in Plants, 4th Edition

edited by

Quan Zou

, Ran Su and Qiangguo Jin

submission deadline 31 Oct 2026 | 1 articles | Viewed by 276 | Submission Open

Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; GWAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Products to Pharmaceutical Agents: Molecular Mechanisms and Therapeutic Applications

edited by

Lele Yang

submission deadline 31 Oct 2026 | Viewed by 243 | Submission Open

Keywords: molecular biology; type 2 diabetes mellitus; natural products; drug discovery; therapeutic applications

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Research on Metabolic Disease

edited by Jianan Zhao

submission deadline 31 Oct 2026 | Viewed by 168 | Submission Open

Keywords: metabolic diseases; diabetes mellitus; insulin resistance; glucose metabolism; lipid metabolism; diabetic complications; cardiovascular disease; molecular mechanisms; gene expression; therapeutic targets

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Therapeutic Targets in Epilepsy

edited by Daniel Rodrigo Marinowic and William Alves Martins

submission deadline 31 Oct 2026 | Viewed by 146 | Submission Open

Keywords: epilepsy; molecular mechanisms; synaptic plasticity; neuroinflammation; glial cells; pharmacoresistance; therapeutic targets; precision medicine; targeted therapy; neuroimmunology

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Natural Products and Their Antioxidant Roles in Health and Disease

edited by

Kawtar Fikri-Benbrahim

and

Naoufal El Hachlafi

submission deadline 31 Oct 2026 | Viewed by 140 | Submission Open

Keywords: natural products; antioxidants; oxidative stress; molecular mechanisms; bioactive metabolites; essential oils; phytochemistry; chronic diseases; signal transduction; therapeutic applications

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Recent Advances in Virus–Host Interactions: A Molecular Perspective

edited by

Moises Leon-Juarez

submission deadline 31 Oct 2026 | Viewed by 138 | Submission Open

Keywords: virus– host interactions; innate immunity; immune evasion; host factor; viral pathogenesis; omics technologies; antiviral targeting

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanism Influencing the Short- and Long-Term Toxicity of Cancer Treatments

edited by

Giorgio Attinà

submission deadline 31 Oct 2026 | Viewed by 103 | Submission Open

Keywords: anticancer toxicity; chemotherapy; cancer; molecular mechanism; pharmacokinetic biomarkers; precision medicine; survivorship care

(This special issue belongs to the Section Molecular Medicine)

Gynecological Cancers: From Molecular Biology to Therapeutic Advances

edited by Leticia Rangel

submission deadline 31 Oct 2026 | Viewed by 100 | Submission Open

Keywords: gynecological oncology; molecular biology; targeted therapy; Immunotherapy; chemoresistance; signaling pathways; cancer chemotherapy; therapeutic advances; cancer genetics and epigenetics; molecular biomarkers

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Reparative Therapeutic Strategies in Neurodegenerative Diseases

edited by

Cesar Borlongan

and Amir Hadanny

submission deadline 31 Oct 2026 | Viewed by 95 | Submission Open

Keywords: neurodegeneration; cell death signaling; oxidative stress; mitochondrial dysfunction; brain repair

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms Governing Macrophage Function in Human Diseases

edited by Da Mi Kim and Wanbao Yang

submission deadline 31 Oct 2026 | Viewed by 87 | Submission Open

Keywords: macrophage biology; molecular mechanisms of macrophage; immunometabolism; metabolic reprogramming of macrophages; cell– cell interaction; microbiome– macrophage interactions; cancer-associated macrophages; metabolic disorders; neuroinflammation; macrophage-targeted therapies

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Detection and Characterization of Emerging Zoonotic Diseases

edited by

Xueyong Zhang

and

Xiaofei Shang

submission deadline 31 Oct 2026 | Viewed by 85 | Submission Open

Keywords: emerging zoonotic diseases; molecular detection; epidemiology; pathogen ecology; molecular biology; pathogen– host interaction; detection methodology; fundamental etiology

(This special issue belongs to the Section Molecular Microbiology)

Early Molecular Diagnosis and Comprehensive Treatment of Tumors, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 31 Oct 2026 | Viewed by 84 | Submission Open

Keywords: next-generation sequencing (NGS); novel biomarkers; precision medicine; targeted therapy; immunotherapy; integrative treatment; personalized cancer treatment

(This special issue belongs to the Section Molecular Medicine)

Recent Progress in Antiparasitic Drugs

edited by

Xiaofei Shang

submission deadline 31 Oct 2026 | Viewed by 81 | Submission Open

Keywords: parasitic diseases; antiparasitic drug; antiparasitic resistance; parasitic control; parasitic infections; antiparasitic targets

(This special issue belongs to the Section Molecular Pharmacology)

Insect–Derived Natural Products: Bioactivity Mechanisms and Applications

edited by

Xuepeng Chi

and Ying Wang

submission deadline 31 Oct 2026 | Viewed by 80 | Submission Open

Keywords: insect-derived bioactive compounds; natural products; molecular mechanisms; biosynthesis; drug discovery; biopesticides; antimicrobial peptides; functional applications; biotechnology; sustainable utilization

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Antimicrobial or Antibiofilm Activity of Biodegradable Substances

edited by

Miyako Yoshida

submission deadline 20 Nov 2026 | 2 articles | Viewed by 4280 | Submission Open

Keywords: antibacterial; antibiofilm; antimicrobial; biodegradable; drug-resistance

(This special issue belongs to the Section Molecular Microbiology)

Novel Drugs and Natural Products Discovery—2nd Edition

edited by

Muhammad Khattab

submission deadline 25 Nov 2026 | 2 articles | Viewed by 740 | Submission Open

Keywords: natural products; novel drugs; drug design

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Targeted Therapeutic Approaches in Cancer: Combining Natural Compounds and Conventional Drugs

edited by

Alok Bhushan

submission deadline 30 Nov 2026 | 5 articles | Viewed by 8323 | Submission Open

Keywords: natural compounds; cancer; repurposing; combination; polychemotherapy; pharmaceuticals; nutraceuticals; molecular targets; metabolomics; immunotherapy

(This special issue belongs to the Section Molecular Medicine)

Mechanistic Insights into the Antioxidant Activity of Bioorganic Molecules: A Chemical Perspective

edited by

Tatjana S. Radosavljević

submission deadline 30 Nov 2026 | 4 articles | Viewed by 7779 | Submission Open

Keywords: antioxidant mechanisms; bioorganic molecules; redox -active compounds; molecular reactivity; oxidative stress modulation

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Pathogenesis, Diagnosis and Treatment of Skin and Sexually Transmitted Diseases

edited by

Maria Eleni Manthou

, Efstratios Vakirlis and

Iasonas Dermitzakis

submission deadline 30 Nov 2026 | 5 articles | Viewed by 6898 | Submission Open

Keywords: pathogenesis; diagnosis; treatment; dermatology; STDs; molecular; immunology; inflammation; genomics; precision

(This special issue belongs to the Section Molecular Medicine)

Abiotic Stress in Plants

edited by

Edgar Omar Rueda-Puente

submission deadline 30 Nov 2026 | 5 articles | Viewed by 5228 | Submission Open

Keywords: plant growth; abiotic stress; abiotic stress tolerance; gene editing

(This special issue belongs to the Section Molecular Plant Sciences)

Bioinformatics Research in Bacterial Genomics, Metagenomics and Metatranscriptomics: 2nd Edition

edited by

Vesselin Baev

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4921 | Submission Open

Keywords: bacterial genomics and functional analysis; genome-wide comparative genomics; bioinformatics methods and tools; metagenomics; metatranscriptomics

(This special issue belongs to the Section Molecular Microbiology)

Gastrointestinal Cancers: From Pathogenesis to Treatment

edited by

Mingwei Lin

and

Cheng-Che Lee

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3270 | Submission Open

Keywords: gastric cancer; cancer stem cells (CSCs); Nrf2 signaling; chemoresistance; extracellular vesicles (EVs); redox homeostasis

(This special issue belongs to the Section Molecular Medicine)

Harnessing Genomic Data for Disease Understanding and Drug Discovery

edited by

Gaurav Tripathi

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3168 | Submission Open

Keywords: pharmacogenomics; genomics; transcriptomics; epigenomics; drug discovery

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Basis of Autoimmune Diseases

edited by

Ranjeet Singh Mahla

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2814 | Submission Open

Keywords: autoimmune diseases; immune regulation; molecular mechanisms; genetic predisposition; epigenetics; cytokines; biomarkers; immune checkpoints; targeted therapies; genomics; transcriptomics; proteomics; systems biology; inflammation; immune tolerance

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Pathogen–Host Interactions and Therapeutic Development

edited by

Sherif T.S. Hassan

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1613 | Submission Open

Keywords: bacterial infections; fungal infections; viral infections; infectious microorganisms; molecular medicine techniques; diagnosis; treatment; and prevention approaches; molecular and physiological investigations; cellular and genetic studies; disease pathogenesis; computational methods; drug design and development

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Immunological Research on Colorectal Cancer: Pathogenesis, Microenvironment, and Future Therapies

edited by Mónica G Mendoza-Rodríguez

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1532 | Submission Open

Keywords: colorectal cancer (CRC); tumor microenvironment; chemotherapy resistance; inflammation-related signalling; biotherapeutics; immune response; cancer progression

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Products and Their Derivatives as Antitumor Agents

edited by

Branislav Nastasijevic

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1530 | Submission Open

Keywords: anticancer drug screening; derivatives of natural compounds; targeted cancer therapy; multi-target therapy; cancer drug resistance; drug repurposing; anticancer drug bioavailability; antiproliferative activity; natural products as radiosensitizers; natural products as radioprotectors; natural remedies for chemotherapy side effects

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Gene Expression and Regulation in Cancer

edited by

Karolina Bajdak-Rusinek

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1312 | Submission Open

Keywords: cancer gene expression; oncogenic regulatory mechanisms; gene regulation targeted therapy; tumor phenotypes; cancer diagnostics and treatment

(This special issue belongs to the Section Molecular Medicine)

Phytochemical-Based Therapeutics: Emerging Mechanisms and Biomedical Applications

edited by

Yoon-Jin Lee

submission deadline 30 Nov 2026 | 1 articles | Viewed by 687 | Submission Open

Keywords: phytochemicals; therapeutic mechanisms; natural products; signal transduction; bioactivity; drug delivery; translational research; biomedical applications

(This special issue belongs to the Section Molecular Medicine)

Autophagy Dysfunction in Neurodegenerative Disease

edited by

Federica Morani

and

Stefano Doccini

submission deadline 30 Nov 2026 | 1 articles | Viewed by 580 | Submission Open

Keywords: autophagy; neurodegeneration; neurodegenerative diseases; autophagy dysfunction; lysosome; autophagosome; mitophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Exploring Novel Therapeutic Targets for Neuropsychiatric Disorders: Current Research and Future Direction

edited by Claudia Bregonzio

submission deadline 30 Nov 2026 | Viewed by 323 | Submission Open

Keywords: microvascular alterations; Parkinson’ s disease; Alzheimer disease; schizophrenia; depression

(This special issue belongs to the Section Molecular Medicine)

Extracellular Proteostasis and Chaperone Networks in Neurodegeneration

edited by

Nicholas J. Geraghty

submission deadline 30 Nov 2026 | Viewed by 202 | Submission Open

Keywords: protein aggregation; extracellular chaperone; receptor-mediated endocytosis; protein clearance; neuronal stress response; protein trafficking; clusterin; haptoglobin; α 2-macroglobulin

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Nanomedicines in Cancers Targeting and Therapy

edited by

Wei Jiang

submission deadline 30 Nov 2026 | Viewed by 170 | Submission Open

Keywords: nanomedicine; tumor targeting; cancer therapy; drug delivery vehicle; biomedical

(This special issue belongs to the Section Molecular Medicine)

Innovative and Advanced Approaches in Drug Design and Discovery

edited by

Mohammed Bouachrine

submission deadline 30 Nov 2026 | Viewed by 152 | Submission Open

Keywords: drug design; drug discovery; molecular docking; virtual screening; molecular modeling; artificial intelligence; machine learning; cheminformatics; ADMET prediction; target identification

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity, 2nd Edition

edited by Bogdana Virgolici

submission deadline 30 Nov 2026 | Viewed by 108 | Submission Open

Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction

(This special issue belongs to the Section Molecular Medicine)

Pharmacology of Neuroprotection: Strategies, Compounds, and Drug Repurposing—a Regional Perspective from Bulgaria

edited by

Stela Dragomanova

submission deadline 30 Nov 2026 | Viewed by 106 | Submission Open

Keywords: neurodegenerative diseases; neuroprotection; multi-target pharmacology; natural compounds and drug repurposing; biological therapies and translational pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms in Cancer Treatment and Anticancer Drugs

edited by

Roberto Campagna

and Valentina Schiavoni

submission deadline 30 Nov 2026 | Viewed by 100 | Submission Open

Keywords: anticancer drugs; molecular mechanisms; drug resistance; targeted therapy; signaling pathways; tumor biology; precision oncology; epigenetics; cancer metabolism; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Integrative Multi-Omics and Transcriptomic Profiling of Reproductive Tract Disorders: From Molecular Mechanisms to Precision Medicine

edited by

Ahsanullah Unar

submission deadline 30 Nov 2026 | Viewed by 97 | Submission Open

Keywords: multi-omics; transcriptomics; reproductive tract disorders; gynecological cancers; male infertility; single-cell sequencing; spatial transcriptomics; machine learning; precision medicine; biomarkers

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Mechanisms of Therapy and Stress Responses in Cancer Cells and Normal Tissues

edited by

Ratan Sadhukhan

submission deadline 30 Nov 2026 | Viewed by 91 | Submission Open

Keywords: cancer therapeutics; radiotherapy; DNA damage; cellular stress response; genome integrity; DNA repair; tumor cells; normal tissue toxicity

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Nutrition and Immune Function in Disease: From Mechanisms to Precision Medicine

edited by

Liang Chen

submission deadline 30 Nov 2026 | Viewed by 79 | Submission Open

Keywords: nutrition–immune interactions; immunometabolism; inflammation; sarcopenia; precision medicine

(This special issue belongs to the Section Molecular Medicine)

State-of-the-Art Molecular Skin Research in the Republic of Korea

edited by

Sullim Lee

submission deadline 30 Nov 2026 | Viewed by 33 | Submission Open

Keywords: natural products; bioactive compounds; skin biology; dermatological health; skin aging; skin barrier; keratinocytes; dermal fibroblasts; pigmentation; inflammation; oxidative stress; extracellular matrix (ECM); collagen; matrix metalloproteinases (MMPs); cellular senescence; signal transduction; molecular mechanisms; cosmeceuticals; functional ingredients; phytochemicals; marine-derived compounds; microbial metabolites

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Potential Applications of Bioactive Plants and Their Natural Products

edited by

Mónica Lizeth Chávez-González

submission deadline 30 Nov 2026 | Viewed by 31 | Submission Open

Keywords: bioactive plants; natural products; molecular mechanisms; phytochemicals; secondary metabolites; functional applications; plant-derived bioactives

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Mechanisms of Intervertebral Disc Degeneration and Regeneration

edited by

Koji Akeda

, Nobuyuki Fujita and Akira Shinohara

submission deadline 10 Dec 2026 | Viewed by 306 | Submission Open

Keywords: intervertebral disc degeneration; disc regenerative therapy; biomechanics of the spine; molecular mechanisms; degenerative lumbar disorders

(This special issue belongs to the Section Molecular Medicine)

Molecular Research on Metabolic Aberration-Driven Carcinogenesis

edited by John Joseph Byrnes

submission deadline 30 Dec 2026 | 1 articles | Viewed by 827 | Submission Open

Keywords: metabolic disorders; carcinogenic mutations; carcinogenesis; obesity-associated cancers; metabolic signaling

(This special issue belongs to the Section Molecular Medicine)

Natural Phytochemicals as Modulators of Cellular Pathways and Therapeutic Targets in Disease Models

edited by

Jui-Hung Yen

submission deadline 31 Dec 2026 | 2 articles | Viewed by 9157 | Submission Open

Keywords: phytochemicals; cellular signaling pathways; disease models; therapeutic targets; synergistic effects; natural products; bioactive modulators

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Latest Review Papers in Molecular Biology 2026

edited by

Madhav Bhatia

submission deadline 31 Dec 2026 | 8 articles | Viewed by 8331 | Submission Open

Keywords: molecular biology; molecular plant sciences; molecular cell biology; molecular medicine; molecular pathology

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Roles of Neutrophil Extracellular Traps in Immune Responses and Disease

edited by Sofía S. Jerez

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2669 | Submission Open

Keywords: neutrophils; NET; inflammation; chronic diseases; cell death

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Vascular Biology in Health and Diseases

edited by

Nilanjana Maulik

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1926 | Submission Open

Keywords: vascular biology; vascular disease; endothelium; cardiovascular disease (CVD); pathological mechanisms

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms of Plant Stress Responses and Development

edited by

Abdul Wakeel Umar

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1787 | Submission Open

Keywords: plant stress physiology; hormonal signaling networks; abiotic stress tolerance; transcriptional regulation; epigenetics and chromatin dynamics; multi-omics integration; secondary metabolite biosynthesis; developmental plasticity; signal transduction; ROS and redox regulation; synthetic biology; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

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