Molecular Mechanism of HPV’s Involvement in Cancers, 2nd Edition
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 34
Special Issue Editor
Interests: assisted reproductive technology; cancer biology; hCG beta and epithelial cancers; HPV; nanotechnology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Human papillomavirus (HPV) can cause cancer at multiple anatomical sites in both men and women. The expression of high-risk HPV types E6/E7 initiates a process of malignant transformation, including the evasion of cell cycle control, the inhibition of apoptosis, and the activation of proliferation-promoting gene transcription. HPV in vitro models and transgenic mouse models have been generated and characterized, and they provide a good platform for understanding the biological properties of HPV genes; however, further studies which consider the differences between molecular profiling and possible therapeutic targets between HPV-positive and HPV-negative cancers are needed to understand whether specific changes promote HPV-associated tumorigenesis.
In this second edition of our Special Issue, we welcome research papers focusing on HPV or HPV-related cancers. Potential topics of interest include (but are not limited to) the following:
- The role of HPV in various cancers, including the molecular pathways of HPV-related cancers and experimental models for studying HPV-related cancers.
- The ways in which studying HPV-related pathways that lead to carcinogenesis will improve our understanding of HPV carcinogenesis.
- HPV genotyping, immune balance, and escape between HPV subtypes and other viruses, as well as immune intervention in HPV infection.
- Novel therapeutic molecular targets and their therapeutic effects for HPV-associated cancers.
Dr. Xuesong Wen
Guest Editor
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Keywords
- HPV
- HPV carcinogenesis
- viral interaction
- HPV genotyping
- head and neck cancer
- immune balance
- cervical cancer
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