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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mycobacterial Infections: Redox Modulation, Cytokine Reprogramming, and Host-Directed Therapy

edited by

Vishwanath Venketaraman

submission deadline 31 Aug 2026 | Viewed by 161 | Submission Open

Keywords: TB; NTM; redox imbalance; cytokine reprogramming; host-directed therapy

(This special issue belongs to the Section Molecular Microbiology)

Molecular Characteristics and Diagnostic Biomarkers in Tumors

edited by Anjali Seth and Israh Akhtar

submission deadline 31 Aug 2026 | Viewed by 157 | Submission Open

Keywords: tumor molecular profiling; diagnostic biomarkers; precision oncology; cancer genomics

(This special issue belongs to the Section Molecular Medicine)

Molecular and Cellular Mechanisms of Neurodegenerative Disease

edited by

Chryssa Bekiari

and

Anastasia Tsingotjidou

submission deadline 31 Aug 2026 | Viewed by 154 | Submission Open

Keywords: Alzheimer’ s disease; neurodegeneration; functional neuroanatomy; transgenic animal models; brain imaging

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Redox Imbalance and Inflammatory Signaling in Disease Mechanisms and Therapeutic Strategies

edited by

Dušan T. Sokolović

and

Nikola Stojanović

submission deadline 31 Aug 2026 | Viewed by 152 | Submission Open

Keywords: redox signaling; inflammatory; oxinflammation

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Emerging Trends for Genome-Wide Association Studies in Complex Disease Genetics

edited by

Xiaowei Wu

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3529 | Submission Open

Keywords: GWAS; polygenic risk scores; rare variants; structural variants; multi-omics; Mendelian randomization; population structure and relatedness; machine learning; Bayesian models; stochastic models

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Mechanisms of Natural Product-Induced Immune Modulation: From Signaling Pathways to Therapeutic Targets

edited by Suyun Lyu

submission deadline 20 Sep 2026 | 4 articles | Viewed by 3403 | Submission Open

Keywords: natural products; immunomodulation; immune responses; molecular mechanisms; immune cell activation; inflammation pathways; autoimmune diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Precision Molecular Oncology: From Tumor Biomarker Discovery to Next-Generation Drug Delivery

edited by

Farhadul Islam

submission deadline 20 Sep 2026 | 1 articles | Viewed by 2882 | Submission Open

Keywords: precision oncology; molecular pathology; personalized treatment; tumor marker; biomarkers; multi-omics; drug discovery; nanocarriers; drug delivery; clinical management

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms Driving Cancer Progression and Metastasis

edited by

Karolina Bajdak-Rusinek

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1588 | Submission Open

Keywords: cancer progression; metastasis; epithelial– mesenchymal transition (EMT); tumor plasticity; tumor microenvironment; signaling pathways; therapy resistance

(This special issue belongs to the Section Molecular Medicine)

Molecular Biology and Functional Roles of Tumor Suppressor Genes in Cancer

edited by

Yun Zhang

submission deadline 20 Sep 2026 | 1 articles | Viewed by 596 | Submission Open

Keywords: tumor suppressor genes; cancer biology; TP53; RB1; PTEN; genomic instability; tumor microenvironment; cancer therapy; epigenetic regulation; cell signaling

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research in Bioactivity of Natural Products, 3rd Edition

edited by

Magdalena Bartnik

and

Wirginia Kukula-Koch

submission deadline 30 Sep 2026 | 4 articles | Viewed by 9300 | Submission Open

Keywords: molecular research; molecular properties; metabolic pathway; phytochemicals; natural products; apoptosis; bioactivity assessment; chemical composition; therapeutic targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Effects of Nanoparticles on Living Organisms, 3rd Edition

edited by

Yoshitaka Miyamoto

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6468 | Submission Open

Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological; inflammatory; and allergic diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Neural Networks in Molecular and Cellular Neurobiology

edited by

Paschalis Theotokis

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4309 | Submission Open

Keywords: neural networks; neuroplasticity; intracellular signaling; computational neuroscience; artificial intelligence; neuromorphic computing

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Plant Hormones, Development, and Stress Tolerance

edited by

Zhaohui Chu

and

Wei Yang

submission deadline 30 Sep 2026 | 5 articles | Viewed by 4281 | Submission Open

Keywords: plant hormones; abiotic stress; auxins; jasmonic acid; signal pathway

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Review Papers in Molecular Plant Science 2026

edited by

Zhaohui Chu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3362 | Submission Open

Keywords: multi-omics; plant bioreactor; plant genomics; plant-pathogens interaction; crop domestication; crop yield traits

(This special issue belongs to the Section Molecular Plant Sciences)

Emerging Trends in Bioinformatics and Computational Biology

edited by Haijun Gong

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2416 | Submission Open

Keywords: bioinformatics; computational biology; genomics; proteomics; metabolomics; multi-omics; machine learning; algorithms; big data; molecular diagnostics; personalized medicine; data visualization

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Advances in Molecular Biology and Therapeutics: From Natural Products to Pharmaceutical Agents

edited by

Budimir S. Ilić

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2046 | Submission Open

Keywords: natural products; molecular biology; medicinal chemistry; drug discovery; therapeutic agents; molecular dynamics; QSAR modeling; ADMET profiling; antimicrobial resistance; translational pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Gut Biology: Stem Cells, Organoids, and Microbiota–Immune Interactions

edited by

Shaoyi Zhang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1511 | Submission Open

Keywords: intestinal stem cells; intestinal organoids; gut– microbiota interaction; mucosal immunology; molecular mechanisms; gut epithelial regeneration; microbiota– immune crosstalk; organoid disease models; intestinal homeostasis; molecular gut biology

(This special issue belongs to the Section Molecular Microbiology)

Current Advances in Oxytocin Research, 2nd Edition

edited by

Claudia Camerino

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1358 | Submission Open

Keywords: oxytocin; thermoregulation; skeletal muscle; obesity; Prader– Willi syndrome

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research on Growth Hormones and Related Hormones and Peptides

edited by Hugo Alberto Barrera-Saldaña

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1190 | Submission Open

Keywords: growth hormones; insulin-like growth factor; prolactin; vasoinhibin; antiangiogenic

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Pharmacotherapeutic Strategies to Prevent Tumor Development, Progression and Treatment Resistance, 3rd Edition

edited by

Peter C. Hart

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: cancer; therapeutic resistance; drug tolerance; mechanisms of tumor development; mechanisms of tumor progression

(This special issue belongs to the Section Molecular Pharmacology)

Advancements in Mass Spectrometry-Based Lipidomics for Molecular Biology Research

edited by Hua Tian

submission deadline 30 Sep 2026 | 1 articles | Viewed by 994 | Submission Open

Keywords: lipidomics; high resolution; spatial omics; single cell

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Biology of Lung Cancer: Pathogenesis and New Therapeutic Strategies

edited by Ting Xu and Nan Li

submission deadline 30 Sep 2026 | 1 articles | Viewed by 888 | Submission Open

Keywords: lung cancer; molecular pathogenesis; oncogenic signaling; tumor microenvironment; targeted therapy; immunotherapy; drug resistance; biomarkers; precision oncology; multi-omics analysis

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Stem Cell-Derived Cells and Bioengineering: Molecular Bases in Regeneration and Disease Research

edited by Aylin Acun

submission deadline 30 Sep 2026 | 1 articles | Viewed by 870 | Submission Open

Keywords: stem cells; regenerative medicine; bioengineering; disease modeling; organoids; tissue engineering; decellularization; bioprinting

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Plant Physiology and Genomic Breeding of Cereals

edited by

Abdullah Shalmani

submission deadline 30 Sep 2026 | 1 articles | Viewed by 805 | Submission Open

Keywords: cereals; molecular physiology; genomic breeding; stress tolerance; functional genomics; genome editing; QTL mapping; multiomics; genotype– environment interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Oxidative Stress and Inflammation

edited by Md. Sohanur Rahman

submission deadline 30 Sep 2026 | 1 articles | Viewed by 743 | Submission Open

Keywords: oxidative stress; inflammation; redox signaling; mitochondrial dysfunction; antioxidant therapy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Recent Advances in Energy Metabolism

edited by

Alexander Panov

submission deadline 30 Sep 2026 | 1 articles | Viewed by 601 | Submission Open

Keywords: energy metabolism; glycolysis; lactate cycle; metabolic flexibility; mitochondria; respirasome; structure-function relations

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Responses of Plants to Abiotic Stress

edited by Tuo Ji and Fengjuan Yang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 588 | Submission Open

Keywords: abiotic stress responses; stress signal transduction; gene functional characterization; multi-omics regulation; crop stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 3rd Edition

edited by Haibo Dong and

Wei Guo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 511 | Submission Open

Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions

(This special issue belongs to the Section Molecular Medicine)

Natural Compounds: An Adjuvant Strategy in Cancer Management, 2nd Edition

edited by Monia Cecati and

Arianna Vignini

submission deadline 30 Sep 2026 | 1 articles | Viewed by 423 | Submission Open

Keywords: cancer; phytochemicals; bioactive compounds; anti-tumor; cancer treatment

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Studies of Bioactive Compounds and Their Therapeutic Potential

edited by Sanja Radman and

Ivana Carev

submission deadline 30 Sep 2026 | Viewed by 310 | Submission Open

Keywords: bioactive compounds; molecular mechanisms; structural elucidation; molecular targets; omics approaches

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Innovative Models for SARS-CoV-2 Pathogenesis

edited by

Virginia Lotti

submission deadline 30 Sep 2026 | Viewed by 232 | Submission Open

Keywords: SARS-CoV-2; coronavirus; virus infection; pathogenesis; innovative models

(This special issue belongs to the Section Molecular Medicine)

Molecular Innovations in Drug Repositioning for Cancer Therapy

edited by

Ewa Trybus

and

Wojciech Trybus

submission deadline 30 Sep 2026 | Viewed by 175 | Submission Open

Keywords: drug repositioning; cancer therapy; therapeutic target identification; signaling pathways; drug development

(This special issue belongs to the Section Molecular Medicine)

Neurochemical and Biochemical Mechanisms of Depressive Disorders

edited by Ana B. Ramos-Hryb and Mauricio Peña Cunha

submission deadline 30 Sep 2026 | Viewed by 153 | Submission Open

Keywords: neurochemical signaling; molecular psychiatry; biochemical biomarkers; synaptic plasticity; neuroinflammation; oxidative stress; glutamatergic system; proteomics and metabolomics; signal transduction; neuroendocrine

(This special issue belongs to the Section Molecular Medicine)

Cellular and Molecular Mechanisms of Epilepsy

edited by Joaquin N. Lugo

submission deadline 30 Sep 2026 | Viewed by 126 | Submission Open

Keywords: pathophysiology; molecular mechanism; circuit; ion channels; comorbidities

(This special issue belongs to the Section Molecular Medicine)

Gene Regulation and Molecular Mechanisms Underlying Plant Responses to Abiotic Stresses

edited by Talles de Oliveira Santos and

Vitor Batista Pinto

submission deadline 30 Sep 2026 | Viewed by 109 | Submission Open

Keywords: abiotic stress tolerance; gene regulation; transcription factors; epigenetic regulation; signal transduction pathways; redox homeostasis; heavy metal toxicity; nutrient imbalance; multi-omics integration; molecular plant physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Therapeutic Advances in Hypertension Management and Vascular Health

edited by

Federica Fogacci

Arrigo Francesco Giuseppe Cicero

and

Claudio Borghi

submission deadline 20 Oct 2026 | 2 articles | Viewed by 6531 | Submission Open

Keywords: hypertension; vascular aging; endothelial dysfunction; gestational hypertension; metabolic disorders; therapeutic strategies in hypertension management

(This special issue belongs to the Section Molecular Medicine)

The Role of Bioactives in Inflammation, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 31 Oct 2026 | 11 articles | Viewed by 14221 | Submission Open

Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Therapeutic Effects of Natural Bioactive Compounds in the Management of Human Diseases: 2nd Edition

edited by

Rossana Morabito

and

Sara Spinelli

submission deadline 31 Oct 2026 | 6 articles | Viewed by 7228 | Submission Open

Keywords: natural bioactive compound; human health; chronic diseases; molecular target; oxidative stress; inflammation; cancer; diabetes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding, 2nd Edition

edited by Chen Chen

submission deadline 31 Oct 2026 | 7 articles | Viewed by 6341 | Submission Open

Keywords: sequencing technologies; plant genomics; transcriptomics; proteomics; metabolomics; epigenomics; single-cell sequencing; functional genomics; transformation methods; gene identification

(This special issue belongs to the Section Molecular Plant Sciences)

Molecules at Play in Cardiovascular Diseases

edited by

Dumitru Iacobas

submission deadline 31 Oct 2026 | 6 articles | Viewed by 6125 | Submission Open

Keywords: arrythmias; arteriosclerosis; congenital heart disease; coronary disease; diabetic cardiomyopathy; dilated cardiomyopathy; endocarditis; high blood pressure; hypertrophic cardiomyopathy; valvular heart diseases

(This special issue belongs to the Section Molecular Medicine)

Hyperlipidemia and Molecular Mechanism in Human and Animals

edited by

Kyuhyung Choi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 3977 | Submission Open

Keywords: hyperlipidemia; diabetes mellitus; Cushing’ s disease; pancreatitis; gall bladder mucoceles

(This special issue belongs to the Section Molecular Medicine)

Advances in Drug Delivery: Molecular Mechanisms, Therapeutic Applications, and Technologies

edited by

Wenhao Wang

and

Zhengwei Huang

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3935 | Submission Open

Keywords: drug delivery; stimulus-responsive drug delivery systems; controlled-release drug delivery systems; theranostics; carrier– biological system interactions; delivery barriers; molecular mechanisms

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research on Free Radicals and Oxidative Stress—2nd Edition

edited by

Mosharraf Sarker

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2092 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); gene regulation; antioxidants; mitochondrial dysfunction; insulin resistance; inflammation; autophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Bioinformatics in Human Disease Network Analysis

edited by

Li Liao

submission deadline 31 Oct 2026 | 3 articles | Viewed by 1269 | Submission Open

Keywords: human interactome; comorbidity; disease network; disease interaction; genotype; gene– gene interaction; graph analysis

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Mechanisms of Radiation-Induced Cellular Responses

edited by

Amparo Olivares

and

Miguel Alcaraz Baños

submission deadline 31 Oct 2026 | 1 articles | Viewed by 998 | Submission Open

Keywords: ionizing radiation; oxidative stress; radioprotectors; radiosensitizers; antioxidant defenses; cancer therapy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Multiomics of Cancer Research in Human and Animals

edited by

Kyuhyung Choi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 557 | Submission Open

Keywords: multiomics; cancer; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Cutting-Edge Microscopy and Electron Microscopy Innovations in Molecular Biology Research

edited by

Diana Torge

submission deadline 31 Oct 2026 | Viewed by 493 | Submission Open

Keywords: morphology; microscopy; transmission electron microscopy; molecular biology; medicine; dentistry

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

The Contribution and Application of Molecular Biology in the Applied Biosciences—Focusing on Medicine, Biomaterials and Tissue Engineering Fields, 3rd Edition

edited by

Ioannis Tsamesidis

and

Evangelia Stalika

submission deadline 31 Oct 2026 | 2 articles | Viewed by 423 | Submission Open

Keywords: medicine; biomaterials; tissue engineering; molecular biology; patients’ reported outcomes; personalized medicine

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Epigenetics and Chromatin Remodeling in Cancer

edited by

Gianluca Tedaldi

and

Alessandra Virga

submission deadline 31 Oct 2026 | Viewed by 409 | Submission Open

Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy

(This special issue belongs to the Section Molecular Medicine)

Scoliosis and Spinal Disorders: Molecular Biomarkers and Therapeutic Strategies

edited by

Angelos Kaspiris

submission deadline 31 Oct 2026 | Viewed by 371 | Submission Open

Keywords: intracellular interactions during the progression of spinal disorders; molecular signaling in scoliosis; growth factor expression in spinal disorders and deformities; biomarkers; molecular-driven treatment

(This special issue belongs to the Section Molecular Medicine)

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