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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanism of HPV’s Involvement in Cancers
edited by Xuesong Wen
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6539 | Submission Open
Keywords: HPV; HPV carcinogenesis; viral interaction; HPV genotyping; head and neck cancer; immune balance; cervical cancer
(This special issue belongs to the Section Molecular Medicine)
Functional Genomics and Comparative Genomics Analysis in Plants, 3rd Edition
edited by , Ran Su and Qiangguo Jin
submission deadline 31 Dec 2025 | 8 articles | Viewed by 5373 | Submission Open
Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; GWAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Pharmacotherapeutic Strategies to Prevent Tumor Development, Progression and Treatment Resistance, 2nd Edition
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 5074 | Submission Open
Keywords: cancer; therapeutic resistance; drug tolerance; mechanisms of tumor development; mechanisms of tumor progression
(This special issue belongs to the Section Molecular Pharmacology)
Multiple Myeloma: From Molecular Mechanism to Diagnosis and Therapy
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4518 | Submission Open
Keywords: multiple myeloma; blood cancer; immunopathogenesis; biomarker; immunoglobulin
(This special issue belongs to the Section Molecular Medicine)
Innovations in Marine Biotechnology and Molecular Biology
edited by Huarong Guo
submission deadline 31 Dec 2025 | 4 articles | Viewed by 3948 | Submission Open
Keywords: marine animal; marine algae; marine microorganism; marine biotechnology; molecular biology
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Oral Cancer: Prophylaxis, Etiopathogenesis and Treatment, 2nd Edition submission deadline 31 Dec 2025 | 3 articles | Viewed by 3905 | Submission Open
Keywords: oral carcinogenesis; biomarkers; cell signaling; natural products; phytochemicals; medicinal plants; essential oils; antimicrobial activity; cytotoxicity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation
(This special issue belongs to the Section Molecular Medicine)
New Immunological Therapeutic Strategies in Kidney Disease
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2889 | Submission Open
Keywords: IgA nephritis; IL-23/IL-17 pathway; CAR T-cell therapy; mesenchymal stem cells; innate lymphoid cells
(This special issue belongs to the Section Molecular Medicine)
Phytochemicals in Cancer Chemoprevention and Treatment: 2nd Edition submission deadline 31 Dec 2025 | 3 articles | Viewed by 2609 | Submission Open
Keywords: phytochemicals; chemoprevention; cancer therapy; oxidative stress; apoptosis; autophagy; mitotic catastrophe; cell cycle; cytotoxicity; DNA damage; molecular pathways
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Insights into Cancer Biomarkers: Identification and Practical Applications submission deadline 31 Dec 2025 | 3 articles | Viewed by 2561 | Submission Open
Keywords: cancer biomarkers; liquid biopsy; early detection; progression; prognosis; treatment monitoring
(This special issue belongs to the Section Molecular Medicine)
The Molecular Basis of Immunotherapy in Cancer Treatment
edited by Hassan Dastsooz
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1526 | Submission Open
Keywords: immunotherapy; cancer; CAR-T cell therapy; monoclonal antibodies; immunomodulation; cytokines; immune evasion mechanisms
(This special issue belongs to the Section Molecular Medicine)
Feature Papers in Molecular Medicine 2025 submission deadline 31 Dec 2025 | 2 articles | Viewed by 1270 | Submission Open
Keywords: pathogenesis; angiogenesis; autoimmune diseases; inflammatory; cancer; cardiovascular diseases; development and differentiation; endocrinology; genetics; epigenetics; hematology; hypoxia research; immunology; infectious diseases; metabolic disorders; neuroscience of diseases; regenerative medicine; prevention; therapeutics; stem cell research
(This special issue belongs to the Section Molecular Medicine)
Advances in Molecular Therapies and Disease Associations in Diabetes
edited by and Shaolei Teng
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1085 | Submission Open
Keywords: diabetes; molecular therapies; comorbidities; genomics; proteomics; metabolomics; multi-omics; precision medicine
(This special issue belongs to the Section Molecular Medicine)
Molecular Functions of Long Non-Coding RNAs: Implications for Diseases and Therapy submission deadline 31 Dec 2025 | 1 articles | Viewed by 1066 | Submission Open
Keywords: long non-coding RNAs (lncRNAs); gene regulation; molecular mechanisms; chromatin remodeling; epigenetic control; disease pathophysiology; biomarker discovery; therapeutic strategies; translational research
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Applications of Natural and Pseudo-Natural Products in Drug Discovery and Development 2025
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 498 | Submission Open
Keywords: natural products; pseudo-natural products; drug discovery; molecular level; in vitro studies; in vivo studies; computational methods; mode of action; computational methods
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Mechanism and Advances in Gynecological Pathology: From Bench to Bedside
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 399 | Submission Open
Keywords: gynecological cancers; molecular pathology; biomarkers; genetic alterations; epigenetics; tumor microenvironment; personalized medicine; targeted therapy; endometriosis; ovarian cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Advances in piRNA Biology and Processing: Mechanisms and Applications
edited by
submission deadline 31 Dec 2025 | Viewed by 326 | Submission Open
Keywords: piRNA; Piwi; transposable elements; epigenetics; genetics; development; cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Advances in Bioinformatics and Molecular Research on Alzheimer’s Disease
edited by Aristidis G. Vrahatis
submission deadline 31 Dec 2025 | Viewed by 258 | Submission Open
Keywords: Alzheimer’ s disease; single-cell sequencing; molecular biomarkers; single-cell RNA-seq; single-cell ATAC-seq; spatial transcriptomics
(This special issue belongs to the Section Molecular Medicine)
Design and Synthesis of Bioactive Peptides and Molecular Conjugates for Targeted Drug Delivery
edited by
submission deadline 31 Dec 2025 | Viewed by 184 | Submission Open
Keywords: peptides; non-covalent synthesis; fluorescent probes; biomaterials; stimuli-responsive; hydrogels; site specific; drug delivery
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Biomaterials for Disease Diagnosis and Therapy: Emerging Molecular Innovations and Applications
edited by Md Tipu Sultan
submission deadline 31 Dec 2025 | Viewed by 83 | Submission Open
Keywords: biomaterials; disease diagnosis; nanoparticles; hydrogels; scaffolds; bio 3D printing; bioink; biosensors; drug delivery; tissue engineering; biocompatibility; translational medicine; cancer; neurodegenerative disorders; disease model; 3D-printed microfluidic devices; organ on a chip; 3D-printed medical devices
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
New Advances in Plant Responses to Environmental Stresses
edited by
submission deadline 31 Dec 2025 | Viewed by 79 | Submission Open
Keywords: abiotic stress; functional proteomics; stress response; salt stress; heavy metal stress
(This special issue belongs to the Section Molecular Plant Sciences)
Targeted Therapies and Biomarker Discovery in Health and Disease submission deadline 31 Dec 2025 | Viewed by 47 | Submission Open
Keywords: multi-omics technologies; targeted therapies; biomarkers; oncology; neurology
(This special issue belongs to the Section Molecular Pharmacology)
Innovative Strategies in Overcoming Antimicrobial Resistance: From Phage Therapy to Combination
edited by Rajnikant Sharma
submission deadline 31 Dec 2025 | Viewed by 44 | Submission Open
Keywords: bacteriophages; phage therapy; antimicrobial resistance; phage engineering; phage-antibiotic combination; phage pharmacokinetics
(This special issue belongs to the Section Molecular Microbiology)
Advancements in Dendrimer Technology: From Molecular Biology Applications to Therapeutic Innovations submission deadline 31 Dec 2025 | Viewed by 40 | Submission Open
Keywords: dendrimers; molecular biology applications; therapeutic innovations; nanomedicine; drug delivery
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Breeding and Genetics Research in Plants—3rd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 35 | Submission Open
Keywords: genetic basis; genomic selection/prediction; molecular breeding; biotic and abiotic stresses; qPCR
(This special issue belongs to the Section Molecular Plant Sciences)
Cancer Immunology: Molecular Tools, New Therapeutic Targets, Challenges, and Opportunities
edited by Pablo C. Ortiz-Lazareno
submission deadline 15 Jan 2026 | Viewed by 49 | Submission Open
Keywords: cancer immunology; immune response; immune evasion; immune checkpoints; immune response
(This special issue belongs to the Section Molecular Medicine)
Innovative Therapeutics and Biomarkers in Hepatocellular Carcinoma Research
edited by
submission deadline 20 Jan 2026 | 2 articles | Viewed by 3447 | Submission Open
Keywords: hepatocellular carcinoma; biomarkers; therapeutics; imaging; artificial intelligence; diagnostics
(This special issue belongs to the Section Molecular Medicine)
Molecular Approaches in Early Detection and Targeted Therapies for Pancreatic Cancer submission deadline 25 Jan 2026 | Viewed by 31 | Submission Open
Keywords: pancreatic cancer; early detection; molecular biomarkers; targeted therapy; genomics; tumor microenvironment; precision medicine; transcriptomics; proteomics; cancer diagnostics
(This special issue belongs to the Section Molecular Medicine)
Radiation-Induced Cellular and Molecular Responses
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 6786 | Submission Open
Keywords: radiation; radiobiology; space radiobiology; heavy ions carcinogenesis; LinearNonTreshold; radionuclide therapy; alpha emitters; beta emitters; radiobiology
(This special issue belongs to the Section Molecular Medicine)
Advanced Molecular Research on Hypertensive Disorders of Pregnancy (HDPs)
edited by
submission deadline 31 Jan 2026 | 7 articles | Viewed by 6138 | Submission Open
Keywords: DNA; RNA; protein; microbiome; hypertensive disorders of pregnancy; preeclampsia; epidemiology; meta-analysis
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms in Plant Stress Tolerance
edited by
submission deadline 31 Jan 2026 | 7 articles | Viewed by 6075 | Submission Open
Keywords: plant stress tolerance; molecular mechanisms; stress-responsive gene; signal transduction pathways; epigenetic modifications; phytohormones (ethylene; ABA; SA; JA); reactive oxygen species (ROS); plant– microbe interactions; microbial plant bio-stimulants; omics approaches (genomics; transcriptomics; proteomics; and metabolomics)
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 2nd Edition
edited by Haibo Dong and
submission deadline 31 Jan 2026 | 5 articles | Viewed by 4444 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2680 | Submission Open
Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Food-Derived Natural Products and Their Biological Activities—2nd Edition
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 2389 | Submission Open
Keywords: food compounds; natural products; biologically active compounds; oxidative stress; anticancer; functionality of foods
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Tumor Microenvironment: Crosstalk Between Epigenetics, Metabolism and Immunity
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 1388 | Submission Open
Keywords: tumor microenvironment; epigenetic modifications; metabolic reprogramming; immune escape; tumor metastasis; therapeutic resistance
(This special issue belongs to the Section Molecular Medicine)
Exploring Molecular Pathways in Skin Health and Diseases
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1357 | Submission Open
Keywords: skin health; skin aging; skin disease; molecular pathways; oxidative stress; immune response; inflammatory skin diseases
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Insights: Mechanisms Underlying the Biological Activities of Natural Products—2nd Edition submission deadline 31 Jan 2026 | 2 articles | Viewed by 1052 | Submission Open
Keywords: natural products; molecular mechanisms; biological activities; pharmacodynamics; drug discovery; therapeutic potential; signaling pathways; target identification; pharmacological properties; bioactive compounds
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Advances in Phytochemical Research: Molecular Pathways in Health and Disease submission deadline 31 Jan 2026 | 1 articles | Viewed by 885 | Submission Open
Keywords: phytochemicals; molecular mechanisms; cancer signaling pathways; anti-inflammatory properties; anti-oxidant properties; apoptosis; cardiovascular disorders; metabolic syndromes; chemoprevention
(This special issue belongs to the Section Molecular Medicine)
Molecular and Pharmacological Insights into Bioactive Compounds: Pathways to Therapeutics submission deadline 31 Jan 2026 | 1 articles | Viewed by 836 | Submission Open
Keywords: bioactive compounds; natural products; drug discovery; pharmacology; therapeutic pathways; molecular mechanisms; signal transduction; medicinal chemistry; target identification
(This special issue belongs to the Section Molecular Pharmacology)
Autophagy and the Ubiquitin–Proteasome System: Regulators of Protein Homeostasis, Cell Death, and Disease Pathogenesis
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 678 | Submission Open
Keywords: autophagy; ubiquitin– proteasome system; protein homeostasis; autophagosome; cell death regulation; cancer; Alzheimer's disease
(This special issue belongs to the Section Molecular Medicine)
Plant Hormones, Development, and Stress Tolerance
edited by and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 352 | Submission Open
Keywords: plant hormones; abiotic stress; auxins; jasmonic acid; signal pathway
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition
edited by
submission deadline 31 Jan 2026 | Viewed by 281 | Submission Open
Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19
(This special issue belongs to the Section Molecular Medicine)
Cutting-Edge Microscopy and Electron Microscopy Innovations in Molecular Biology Research
edited by
submission deadline 31 Jan 2026 | Viewed by 148 | Submission Open
Keywords: morphology; microscopy; transmission electron microscopy; molecular biology; medicine; dentistry
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Unraveling the Role of Epigenetics and Molecular Genetics in Disease Progression via the Gut–Brain Axis
edited by Yong-Chan Kim
submission deadline 31 Jan 2026 | Viewed by 44 | Submission Open
Keywords: prion diseases; Parkinson’ s disease; Alzheimer’ s disease; neurodegenerative disease; inflammatory bowel diseases; ulcerative colitis; Crohn’ s disease; brain– gut axis; bioinformatics; polymorphism
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms of Animal Metabolism: Pathophysiological Implications in Tumor Progression submission deadline 31 Jan 2026 | Viewed by 42 | Submission Open
Keywords: animal cancer metabolism; animal tumor diseases; Warburg effect; drug-resistance; therapeutic targets
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Allergic Diseases: Molecular Pathways and Pathogenesis
edited by
submission deadline 31 Jan 2026 | Viewed by 31 | Submission Open
Keywords: allergic diseases; allergic responses; allergic inflammation; immune response; genetics and susceptibility
(This special issue belongs to the Section Molecular Medicine)
Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding, 2nd Edition
edited by Chen Chen
submission deadline 31 Jan 2026 | Viewed by 26 | Submission Open
Keywords: sequencing technologies; plant genomics; transcriptomics; proteomics; metabolomics; epigenomics; single-cell sequencing; functional genomics; transformation methods; gene identification
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Dynamics Simulations in Structural Biology: From Proteins to Complex Biomolecular Systems
edited by
submission deadline 31 Jan 2026 | Viewed by 25 | Submission Open
Keywords: protein; molecular docking; dynamic simulation; biomolecular systems; molecular interactions; structural modification; enzyme activity; biological function; antioxidant activity; infrared spectroscopy
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Innovative Approaches in Bone and Cartilage Regeneration: From Stem Cells to Organoids submission deadline 31 Jan 2026 | Viewed by 24 | Submission Open
Keywords: bone and cartilage biology; physiology; molecular biology; nutraceuticals; regenerative medicine
(This special issue belongs to the Section Molecular Medicine)
Advances in Molecular Biology Methods in Hepatology Research, 2nd Edition submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open
Keywords: hepatic diseases; molecular biology methods; single-cell genomics; single-cell proteomics; hepatic organoids; biomarkers
(This special issue belongs to the Section Molecular Medicine)
Pharmacological Activities and Mechanisms of Action of Natural Products, 2nd Edition
edited by , and Lee Simon Ming-Yuen
submission deadline 31 Jan 2026 | Viewed by 12 | Submission Open
Keywords: natural products; pharmacological activity; molecular mechanisms; therapeutic targets; structure– activity relationships; protein– ligand interactions; cell signaling pathways; enzyme inhibition/activation; molecular targets
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
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