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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Drugs and Natural Products Discovery
edited by
submission deadline 31 Oct 2025 | 10 articles | Viewed by 10942 | Submission Open
Keywords: natural products; novel drugs; drug design
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Complex Molecular Mechanism of Monogenic Diseases: 3rd Edition
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 9754 | Submission Open
Keywords: cystic fibrosis; sickle cell disease; duchenne muscular dystrophy; inherited monogenic disease; molecular mechanisms
(This special issue belongs to the Section Molecular Medicine)
Natural Product Drug Activity and Biomedicine Application
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 6498 | Submission Open
Keywords: natural products; signaling pathways; epignetic regulation; cell communication; molecular biology
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Biology of Viral Replication and Associated Disease Outcomes
edited by Usama Ashraf
submission deadline 31 Oct 2025 | 4 articles | Viewed by 5347 | Submission Open
Keywords: viruses; replication; immunity; pathogenesis; antivirals; immune modulator
(This special issue belongs to the Section Molecular Microbiology)
Challenges and Advances in Bioinformatics and Computational Biology
edited by Haijun Gong
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3621 | Submission Open
Keywords: bioinformatics; computational biology; genomics; proteomics; metabolomics; multi-omics; machine learning; AI; big data; molecular diagnostics; personalized medicine; data visualization
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Molecular Mechanism and Regulation in Neuroinflammation, 2nd Edition
edited by Hung-Pei Tsai
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3460 | Submission Open
Keywords: microglia; glial cells; cytokines; blood– brain barrier; traumatic brain injury; aging; Alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis; multiple sclerosis
(This special issue belongs to the Section Molecular Medicine)
Intestinal Inflammation: From Molecular Mechanisms to Therapeutic Strategies submission deadline 31 Oct 2025 | 2 articles | Viewed by 2736 | Submission Open
Keywords: inflammatory bowel disease; celiac disease; Crohn's Disease; ulcerative colitis; colitis; hemorrhoidal disease
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms of Gut Microbiota in Health, Immunity and Disease
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2538 | Submission Open
Keywords: gut microbiome; immune system; probiotics; prebiotics; microbial metabolites; microbiota– host interactions; gut– brain axis
(This special issue belongs to the Section Molecular Microbiology)
Pathogenesis, Diagnosis and Treatment of Skin and Sexually Transmitted Diseases
edited by , Efstratios Vakirlis and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 932 | Submission Open
Keywords: pathogenesis; diagnosis; treatment; dermatology; STDs; molecular; immunology; inflammation; genomics; precision
(This special issue belongs to the Section Molecular Medicine)
Epigenetic Changes in Cancer: Mechanisms, Biomarkers, and Therapeutic Strategies
edited by Priscilla Brebi-Mieville
submission deadline 31 Oct 2025 | 1 articles | Viewed by 720 | Submission Open
Keywords: epigenetic mechanisms in cancer; epigenetic-based therapies; precision oncology and epigenetics; epigenetic drug development; tumor heterogeneity and epigenetics; epigenetic reprogramming
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Mitochondrial Genomes 2025: Unraveling the Threads of Evolution and Function
edited by Hongyi Liu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 668 | Submission Open
Keywords: mitogenomes; mitochondria genomes; molecular evolution
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Emerging Role of Molecular and Serum Biomarkers in Osteoporosis submission deadline 31 Oct 2025 | Viewed by 273 | Submission Open
Keywords: osteoporosis; biomarkers; PINP; CTX; bone metabolism
(This special issue belongs to the Section Molecular Medicine)
Natural Products in Biomedicine and Pharmacotherapy, 2nd Edition submission deadline 31 Oct 2025 | Viewed by 227 | Submission Open
Keywords: natural products; genetic engineering; pharmacotherapy; anticancer; antimicrobials
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Medicinal Plants and Phytochemicals for the Prevention and Intervention of Metabolic Disease and Its Complications
edited by
submission deadline 31 Oct 2025 | Viewed by 97 | Submission Open
Keywords: metabolic diseases; phytochemicals; medicinal plants; metabolic diseases complications; functional foods
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Oxidative Stress in Cancer Biology submission deadline 31 Oct 2025 | Viewed by 72 | Submission Open
Keywords: reactive oxygen species (ROS); redox homeostasis; oxidative DNA damage; antioxidant defense mechanisms; Nrf2 signaling pathway; mitochondrial dysfunction; tumor microenvironment; cancer cell survival and proliferation
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms and Pharmacological Underlying Cardiorenal Diseases
edited by
submission deadline 31 Oct 2025 | Viewed by 71 | Submission Open
Keywords: hypertension; cardio-renal syndromes; heart failure; chronic kidney disease; hemodialysis; periotenal dialysis
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights and Unique Characteristics in Adolescent and Young Adult Oncology
edited by
submission deadline 31 Oct 2025 | Viewed by 52 | Submission Open
Keywords: adolescent; young adult; biology; treatment; outcome
(This special issue belongs to the Section Molecular Medicine)
Protein Domains: Structure and Molecular Function
edited by Guangfeng Zhou
submission deadline 10 Nov 2025 | 4 articles | Viewed by 9243 | Submission Open
Keywords: protein structure; protein domains; domain classification; protein engineering; protein design; protein modeling; machine learning; deep learning; protein structure prediction; protein function prediction
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Neuropituitary Hormones in Metabolic Disorders
edited by
submission deadline 10 Nov 2025 | Viewed by 87 | Submission Open
Keywords: oxytocin; vasopressin; thermoregulation; obesity; Prader– Willi syndrome; autism spectrum disorder; anorexia nervosa; craniopharyngioma; metabolic disorders; hypothalamic pituitary disorders; oxytocin-deficiency; vasopressin-deficiency
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Modulation of Oxidative Stress: A Global Perspective for Climate Change Adaptation submission deadline 15 Nov 2025 | Viewed by 212 | Submission Open
Keywords: oxidative stress; modulation; climate change; environmental factors; adaption
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Biology in Dentistry: Innovations in Diagnosis, Treatment, and Biomaterials
edited by and Valentina Belli
submission deadline 20 Nov 2025 | 2 articles | Viewed by 3236 | Submission Open
Keywords: oral microbiome; tissue regeneration; biomimetic materials
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Research on Virus-Induced Cellular and Molecular Responses
edited by
submission deadline 30 Nov 2025 | 6 articles | Viewed by 11936 | Submission Open
Keywords: virus infectivity; infectious diseases; cellular stress; autophagy
(This special issue belongs to the Section Molecular Microbiology)
Natural Product in Skin Inflammation and Barrier Function Damage
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 7253 | Submission Open
Keywords: skin inflammation; barrier function damage; natural compounds; antioxidant properties; antiaging
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Radiation Oncology
edited by Allen Chen
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4721 | Submission Open
Keywords: molecular and cellular radiobiology; radiation physics; DNA damage and repair; radiation response; cancers
(This special issue belongs to the Section Molecular Medicine)
Cardiovascular Disease: From Molecular Mechanisms to Therapeutic Innovations
edited by Andrea Marzullo
submission deadline 30 Nov 2025 | 3 articles | Viewed by 3307 | Submission Open
Keywords: cardiovascular pathophysiology; molecular biomarkers; inflammation and oxidative stress; therapeutic targets; lipid metabolism
(This special issue belongs to the Section Molecular Medicine)
Tumor Immunology: From Molecular Mechanisms to Treatment
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2742 | Submission Open
Keywords: cellular metabolism; metabolic reprogramming; immunometabolism; tumor microenvironment; immunotherapy; metabolites; immunosuppression; immune cells; tumor cells
(This special issue belongs to the Section Molecular Medicine)
Omics Analysis for Personalized Medicine submission deadline 30 Nov 2025 | 2 articles | Viewed by 2566 | Submission Open
Keywords: genomics; epigenomics; transcriptomics; proteomics; metabolomics; multi-omics; high throughput; personalized medicine; immune-mediated inflammatory diseases
(This special issue belongs to the Section Molecular Medicine)
Effects of Nanoparticles on Living Organisms, 3rd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1337 | Submission Open
Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological; inflammatory; and allergic diseases
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Advanced Research in Glioblastoma and Neuroblastoma
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1291 | Submission Open
Keywords: glioblastoma; neuroblastoma; neuropharmaceuticals; drug design; blood– brain barrier; molecular therapeutics; brain-tumor biomarkers
(This special issue belongs to the Section Molecular Medicine)
Molecular Keys to Bioactivity: Pharmacophore and SAR Exploration in Organic Compounds
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1264 | Submission Open
Keywords: structure– activity relationship; pharmacophore; chirality; bioactive molecules; morphogenesis; protein targets; membrane interaction; natural products; synthetic organic compounds; drug discovery
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
The Green Revolution in Cancer Research: Bioactive Substances from Plants as Promising Therapeutics
edited by Johura Ansary
submission deadline 30 Nov 2025 | 2 articles | Viewed by 866 | Submission Open
Keywords: bioactive compound; cancer research; plant-derived; anti-cancer properties; therapeutic strategies
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
The Role of Bioactives in Inflammation, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 846 | Submission Open
Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Harnessing Genomic Data for Disease Understanding and Drug Discovery
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 484 | Submission Open
Keywords: pharmacogenomics; genomics; transcriptomics; epigenomics; drug discovery
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Mechanistic Insights into the Antioxidant Activity of Bioorganic Molecules: A Chemical Perspective submission deadline 30 Nov 2025 | Viewed by 111 | Submission Open
Keywords: antioxidant mechanisms; bioorganic molecules; redox -active compounds; molecular reactivity; oxidative stress modulation
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Advances in Drug Delivery: Molecular Mechanisms, Therapeutic Applications, and Technologies
edited by and
submission deadline 30 Nov 2025 | Viewed by 86 | Submission Open
Keywords: drug delivery; stimulus-responsive drug delivery systems; controlled-release drug delivery systems; theranostics; carrier– biological system interactions; delivery barriers; molecular mechanisms
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Natural Phytochemicals as Modulators of Cellular Pathways and Therapeutic Targets in Disease Models
edited by
submission deadline 30 Nov 2025 | Viewed by 83 | Submission Open
Keywords: phytochemicals; cellular signaling pathways; disease models; therapeutic targets; synergistic effects; natural products; bioactive modulators
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Exploring Novel Therapeutic Targets for Neuropsychiatric Disorders: Current Research and Future Direction
edited by Claudia Bregonzio
submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open
Keywords: microvascular alterations; Parkinson’ s disease; Alzheimer disease; schizophrenia; depression
(This special issue belongs to the Section Molecular Medicine)
Repurposing and Innovation: Drug Research in Neuroprotection
edited by
submission deadline 30 Nov 2025 | Viewed by 70 | Submission Open
Keywords: neuroprotection; drug repurposing; natural-derived compounds; neurodegenerative diseases; pharmacological innovation
(This special issue belongs to the Section Molecular Pharmacology)
Novel Pharmacological Strategies and Molecular Mechanisms in Nonclinical Research
edited by
submission deadline 30 Nov 2025 | Viewed by 64 | Submission Open
Keywords: molecular pharmacology; drug targets; signal transduction pathways; nonclinical models; receptor-ligand interactions; pharmacogenomics; preclinical drug development; gene expression modulation; mechanism of action; translational pharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms and Biomarker Discovery in Neurodegenerative Disorders submission deadline 30 Nov 2025 | Viewed by 60 | Submission Open
Keywords: neurodegenerative diseases; molecular biomarkers; cerebrospinal fluid (CSF) biomarkers; positron emission tomography (PET); seeding amplification assay (SAA); plasma biomarkers
(This special issue belongs to the Section Molecular Medicine)
Advancements in Biomedical Optics and Brain Metabolism
edited by Jennifer M. Lynch
submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open
Keywords: biomedical optics; brain metabolism; optical neuroimaging; cerebral blood flow; near-infrared spectroscopy; diffuse correlation spectroscopy; neurocritical care; noninvasive monitoring; optical biomarkers; brain health
(This special issue belongs to the Section Molecular Medicine)
Molecular Biology and Biochemistry of Cannabis: Exploring the Genetic and Metabolic Pathways
edited by Craig M. Schluttenhofer
submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open
Keywords: cannabis sativa; molecular biology; phytochemical pathways; cannabinoid receptors; genomics; neurobiology; immunomodulation; plant– microbe interactions
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Biochar as a Soil Amendment: Unraveling Molecular Mechanisms Underpinning Plant Growth Promotion via Gene Expression and Regulatory Networks submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open
Keywords: biochar; soil amendment; plant growth promotion; soil health; soil fertility; nutrient availability; rhizosphere interactions; agricultural productivity; sustainable soil management; organic amendments
(This special issue belongs to the Section Molecular Plant Sciences)
Future Challenges of Targeted Therapy of Cancers: 2nd Edition
edited by
submission deadline 10 Dec 2025 | 8 articles | Viewed by 7765 | Submission Open
Keywords: biomarkers; tumor tissue; individualized therapy; gene profile; epithelial– mesenchymal transition; immunotherapy; angiogenesis; metastases; oncology; pathology
(This special issue belongs to the Section Molecular Medicine)
Latest Review Papers in Molecular Biology 2025
edited by
submission deadline 31 Dec 2025 | 15 articles | Viewed by 22844 | Submission Open
Keywords: molecular biology; molecular plant sciences; molecular cell biology; molecular medicine; molecular pathology
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Technological Advances Around Next-Generation Sequencing Application
edited by
submission deadline 31 Dec 2025 | 7 articles | Viewed by 14968 | Submission Open
Keywords: next-generation sequencing; single-cell sequencing; long-read sequencing; metagenomics; epigenomics; cancer genomics; clinical applications; liquid biopsy; CRISPR-Cas9; precision medicine; personalized healthcare
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Natural Compounds: An Adjuvant Strategy in Cancer Management
edited by Monia Cecati and
submission deadline 31 Dec 2025 | 7 articles | Viewed by 9326 | Submission Open
Keywords: cancer; phytochemicals; bioactive compounds; anti-tumor; cancer treatment
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Recombinant Proteins for Molecular Biology Research: Technologies and Applications submission deadline 31 Dec 2025 | 6 articles | Viewed by 8155 | Submission Open
Keywords: recombinant proteins; vaccine; intra-cellular signaling factors; membrane proteins; drug targets
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Effects of Environmental Factors on Cardiovascular Disease: From Molecular Effects to Possible Future Clinic Application submission deadline 31 Dec 2025 | 5 articles | Viewed by 7054 | Submission Open
Keywords: environmental factors; cardiovascular diseases; disease and chronic risk; health status; healthy eating; healthy lifestyle; physical activity; alcohol consumption reduction; tobacco cessation; public health; population health; psychosocial factors; dietary recommendations; nutrient intake; health outcomes
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Contribution and Application of Molecular Biology in the Applied Biosciences—Focusing on Medicine, Biomaterials and Tissue Engineering Fields, 2nd Edition submission deadline 31 Dec 2025 | 5 articles | Viewed by 6598 | Submission Open
Keywords: medicine; biomaterials; tissue engineering; molecular biology; patients’ reported outcomes; personalized medicine
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
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