Allergic Diseases: Molecular Pathways and Pathogenesis
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editor
Interests: respiratory diseases; infectious diseases; bioinformatics; molecular medicine; global health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We welcome contributions for our upcoming Special Issue, “Allergic Diseases: Molecular Pathways and Pathogenesis”. This Special Issue will provide an in-depth exploration of the molecular mechanisms and pathogenesis underlying allergic diseases, focusing on the fundamental molecular pathways that drive allergic responses. Allergic diseases, such as asthma, rhinitis, atopic dermatitis, and food allergies, represent a growing global health concern, and understanding their molecular bases is crucial in order to advance treatment strategies.
This Special Issue will highlight cutting-edge research investigating the molecular pathways and immune mechanisms involved in allergic inflammation. We invite studies examining the roles of immune cells (such as T-helper cells, mast cells, and eosinophils), cytokines, and chemokines in the initiation and progression of allergic responses. This Special Issue will also explore the role of IgE-mediated responses and how they contribute to the pathology of allergic diseases. We encourage contributions that focus on genetic and epigenetic factors influencing allergic disease susceptibility, such as genetic mutations, epigenetic modifications, and non-coding RNAs. Furthermore, this Special Issue will examine the impacts of environmental exposures, such as allergens, pollutants, and microbiome alterations, in the development and exacerbation of allergic diseases.
This Special Issue will also highlight emerging biomarkers for early diagnosis and new therapeutic approaches, with a focus on precision medicine and targeted interventions for allergic diseases. We aim to integrate molecular, cellular, and clinical perspectives to foster a deeper understanding of the mechanisms driving allergic diseases and to contribute to the development of more effective treatments.
We invite original research articles, reviews, and perspectives that address the following themes:
- Molecular Mechanisms Behind Allergic Inflammation: Research investigating the cellular and molecular pathways involved in allergic inflammation, focusing on immune cells (e.g., T-helper cells, mast cells, eosinophils), cytokines, and chemokines;
- IgE-Mediated Responses: Studies exploring the role of IgE in allergic diseases, including its interactions with allergens and its contribution to allergic inflammation and immune response regulation;
- Genetic and Epigenetic Factors in Allergic Disease Susceptibility: Contributions exploring the genetic and epigenetic mechanisms that influence the onset and severity of allergic diseases, including non-coding RNAs;
- Environmental Exposures and Microbiome: Research on how environmental factors, including allergens, pollutants, and microbiome alterations, shape allergic disease pathogenesis and influence disease progression;
- Emerging Biomarkers and Therapeutic Strategies: Investigations into new biomarkers for diagnosis and innovative therapeutic approaches, with an emphasis on precision medicine and targeted therapies.
Submissions are encouraged from researchers across all relevant disciplines, including immunology, molecular biology, genetics, and environmental science. We look forward to receiving contributions that enhance our understanding of allergic diseases from a molecular and pathogenesis perspective.
Kind regards,
Dr. Jing Gao
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- allergic diseases
- allergic responses
- allergic inflammation
- immune response
- genetics and susceptibility
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