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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research into Eye Lens Proteins

edited by

Michel-Edwar Mickael

and Tenzin Tender

submission deadline 31 Mar 2027 | Viewed by 263 | Submission Open

Keywords: alpha-crystallin; eye lens proteins; molecular chaperone; cataracts; neurodegenerative diseases; therapeutic applications

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Preclinical and Clinical Pharmacology

edited by

Maria Bogdan

and

Ianis Kevyn Stefan Boboc

submission deadline 31 Mar 2027 | Viewed by 111 | Submission Open

Keywords: preclinical pharmacology; clinical pharmacology; pharmacokinetics; molecular mechanisms; pharmacodynamics; pharmacogenomics; molecular toxicology; drug safety; targeted therapies; therapeutic efficacy; translational medicine; precision medicine; cellular signaling; drug discovery; in vitro/in vivo models; biomarkers

(This special issue belongs to the Section Molecular Pharmacology)

Design of Peptide-based Hybrid Biomaterials as Drug Delivery Systems

edited by

Ashmeet Singh

submission deadline 31 Mar 2027 | Viewed by 77 | Submission Open

Keywords: peptide-drug conjugates; peptide-functionalized nanoparticles; self-assembling peptide biomaterials; peptide hydrogels; cell-penetrating peptides; targeted nanomedicine; stimuli-responsive drug delivery; blood–brain barrier drug delivery; protein, gene, siRNA, and mRNA delivery; controlled drug release; biomolecular conjugates; clinical translation; computational peptide design and AI

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Crush Syndrome: Molecular Mechanisms and Therapeutic Applications

edited by

Jun Kobayashi

and

Isamu Murata

submission deadline 31 Mar 2027 | Viewed by 58 | Submission Open

Keywords: crush syndrome; ischemia–reperfusion injury; oxidative stress; rhabdomyolysis; reactive oxygen species; molecular biology; mitochondrial dysfunction; proteomics; drug development; immune response

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Targeted Therapies in Respiratory Diseases

edited by

Bianca S. Romero-Martínez

and

Edgar Flores-Soto

submission deadline 31 Mar 2027 | Viewed by 51 | Submission Open

Keywords: respiratory diseases; cell signaling; calcium signaling; lung disease; targeted therapies; hypoxia; cellular senescence; pulmonary inflammation; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Plant-Derived Bioactive Compounds: Molecular Mechanisms, Sustainable Production, and Therapeutic Applications

edited by

Manikandan Gurusamy

and David Katerere

submission deadline 31 Mar 2027 | Viewed by 51 | Submission Open

Keywords: phytochemicals; bioactive compounds; molecular mechanism; sustainable production; therapeutic uses; plant biotechnology; multi-omics; pharmacology; biological activities; drug development

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in Protein–Ligand Interactions: From Theory to Application

edited by

Ahmed Taha

and

Povilas Šimonis

submission deadline 31 Mar 2027 | Viewed by 39 | Submission Open

Keywords: protein–ligand interactions; molecular recognition; binding thermodynamics and kinetics; structural biology; non-covalent interactions; molecular docking and dynamics; artificial intelligence; structure-based drug design; protein engineering

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

State-of-the-Art Molecular Pathology and Therapeutics in Romania

edited by

Claudiu N. Lungu

submission deadline 31 Mar 2027 | Viewed by 37 | Submission Open

Keywords: molecular pathology; precision medicine; therapeutic innovation; multi-omics; biomarker discovery; translational medicine; artificial intelligence in pathology; romanian biomedical research

(This special issue belongs to the Section Molecular Medicine)

Molecular Pathogenesis of Allergic Diseases

edited by Sarah Pedretti

submission deadline 31 Mar 2027 | Viewed by 34 | Submission Open

Keywords: molecular pathogenesis; allergic diseases; immunology; immune dysregulation; allergic inflammation; biomarkers; precision medicine; pharmacogenomics; multi-omics; translational research

(This special issue belongs to the Section Molecular Medicine)

Inflammation and Immune Dysregulation in Cardiovascular Diseases: Molecular Mechanisms and Therapeutic Strategies

edited by

Mehnaz Pervin

submission deadline 31 Mar 2027 | Viewed by 28 | Submission Open

Keywords: inflammation; innate immunity; macrophage signalling; NLRP3 inflammasome; oxidative stress; cardiovascular disease

(This special issue belongs to the Section Molecular Medicine)

Advances in Phytochemical Research: Molecular Pathways in Health and Disease, 2nd Edition

edited by

Christiana Charalambous

and

Christiana M. Neophytou

submission deadline 31 Mar 2027 | Viewed by 25 | Submission Open

Keywords: phytochemicals; molecular mechanisms; cancer signaling pathways; anti-inflammatory properties; anti-oxidant properties; apoptosis; cardiovascular disorders; metabolic syndromes; chemoprevention

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

The Molecular Mechanisms Underlying Neuropsychopharmacology

edited by

Mao-Liang Chen

submission deadline 31 Mar 2027 | Viewed by 19 | Submission Open

Keywords: neuropsychopharmacology; molecular mechanisms; phytochemicals and bioactives; SNARE complex regulation; neurotransmitter release; molecular psychiatry; proteomics and genomics; NMDA receptor hypofunction; synaptic plasticity; translational medicine and RWE

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Cellular Mechanisms of Vascular Function and Dysfunction: Roles of the Endothelium and G-Protein Coupled Receptors

edited by John J. McGuire

submission deadline 10 Apr 2027 | 1 articles | Viewed by 794 | Submission Open

Keywords: endothelium; endothelial cells; vascular smooth muscle; platelets; G-protein coupled receptor; signal transduction; metabolic dysfunction; diabetes; inflammation; angiogenesis

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Gut Biology: Stem Cells, Organoids, and Microbiota–Immune Interactions

edited by

Shaoyi Zhang

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1837 | Submission Open

Keywords: intestinal stem cells; intestinal organoids; gut–microbiota interaction; mucosal immunology; molecular mechanisms; gut epithelial regeneration; microbiota–immune crosstalk; organoid disease models; intestinal homeostasis; molecular gut biology

(This special issue belongs to the Section Molecular Microbiology)

Molecular Biology on Environmental Microorganisms

edited by

Mariusz Cycoń

submission deadline 20 Apr 2027 | 1 articles | Viewed by 748 | Submission Open

Keywords: environmental microbiology; metagenomics; microbial interactions; phage–host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Oxidative Stress in Cancer Biology

edited by

Eugenia Yiannakopoulou

submission deadline 30 Apr 2027 | Viewed by 547 | Submission Open

Keywords: reactive oxygen species (ROS); redox homeostasis; oxidative DNA damage; antioxidant defense mechanisms; Nrf2 signaling pathway; mitochondrial dysfunction; tumor microenvironment; cancer cell survival and proliferation

(This special issue belongs to the Section Molecular Medicine)

Molecular Studies of Bioactive Compounds and Their Therapeutic Potential

edited by Sanja Radman and

Ivana Carev

submission deadline 30 Apr 2027 | Viewed by 399 | Submission Open

Keywords: bioactive compounds; molecular mechanisms; structural elucidation; molecular targets; omics approaches

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Novel Therapeutic Approaches for Targeting Cardiac Fibrosis in Heart Failure

edited by

Samir Bolívar

submission deadline 30 Apr 2027 | Viewed by 77 | Submission Open

Keywords: heart failure; cardiac fibrosis; myocardial remodeling; ventricular dysfunction; antifibrotic treatments; fibroblast activation

(This special issue belongs to the Section Molecular Medicine)

Biologically Active Compounds: Sources, Mechanisms of Action, and Applications, 2nd Edition

edited by Yulian Tumbarski

submission deadline 30 Apr 2027 | Viewed by 74 | Submission Open

Keywords: biologically active compounds; natural products; mechanisms of action; structure–activity relationships; bioavailability; antioxidant activity; antimicrobial activity; anticancer activity; omics approaches; biomedical and industrial applications

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Biomarkers and Omics Approaches in Animal Health, Environmental Toxicology, and One Health

edited by

Bora Florin Dumitru

submission deadline 30 Apr 2027 | Viewed by 11 | Submission Open

Keywords: animal molecular biology; molecular biomarkers; veterinary diagnostics; omics; environmental toxicology; oxidative stress; animal health; sentinel animals; one health; food-chain safety

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Medicinal Plants and Phytochemicals for the Prevention and Intervention of Metabolic Disease and Its Complications

edited by

Sandra Barbalho

submission deadline 31 May 2027 | 1 articles | Viewed by 1106 | Submission Open

Keywords: metabolic diseases; phytochemicals; medicinal plants; metabolic diseases complications; functional foods

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Research on Nerve Damage and Neuroinflammation

edited by Manas Kinra

submission deadline 31 Jul 2027 | 1 articles | Viewed by 448 | Submission Open

Keywords: nerve damage; neuroinflammation; microglia; astrocytes; cytokines; chemokines; oxidative stress; neurodegeneration; blood–brain barrier; drug delivery

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

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